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119 Result(s)
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Article
Open AccessA multimodal physiological and psychological dataset for human with mental stress induced myocardial ischemia
Accurate differentiation between angina with no obstructive coronary arteries (ANOCA) and mental stress-induced myocardial ischemia (MSIMI) is crucial for tailored treatment strategies, yet public data scarcit...
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Open AccessIdentifying the mechanism of polysaccharopeptide against breast cancer based on network pharmacology and experimental verification
Polysaccharopeptide (PSP) is a potential active component in traditional Chinese medicine because of its anticancer effects on a variety of cancer cells and as immune enhancers of the immune system. Previous s...
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Open AccessLoss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1
RNA-binding proteins (RBPs) are critical regulators for RNA transcription and translation. As a key member of RBPs, ELAV-like family protein 2 (CELF2) has been shown to regulate RNA splicing and embryonic hema...
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Open AccessDirect and accurate miRNA detection based on CRISPR/Cas13a-triggered exonuclease-iii-assisted colorimetric assay
The abnormally expressed microRNAs (miRNAs) serve as crucial indicators for disease diagnosis and are strongly associated with the progression of various diseases. The quantification of miRNAs is highly signif...
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Open AccessEpidermolysis Bullosa: Two rare case reports of COL7A1 and EBS-GEN SEV KRT14 variants with review of literature
Bullosa is a rare hereditary skin condition that causes blisters. Genes encoding structural proteins at or near the dermal-epidermal junction are mutated recessively or dominantly, and this is the primary caus...
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RETRACTED ARTICLE: Evolutionary generation of orthomorphisms in the Galois field F28
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Open Access18F-FDG PET/CT-based deep learning radiomics predicts 5-years disease-free survival after failure to achieve pathologic complete response to neoadjuvant chemotherapy in breast cancer
This study aimed to assess whether a combined model incorporating radiomic and depth features extracted from PET/CT can predict disease-free survival (DFS) in patients who failed to achieve pathologic complete...
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Open AccessThrombospondin1 antagonist peptide treatment attenuates obesity-associated chronic inflammation and metabolic disorders in a diet-induced obese mouse model
Thrombospondin1 (TSP1) is a multifunctional matricellular protein. Previously, we demonstrated that TSP1 plays a pivotal role in obesity-related inflammation and insulin resistance (IR) by modulating macrophag...
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Article
Gut microbiota bridges dietary nutrients and host immunity
Dietary nutrients and the gut microbiota are increasingly recognized to cross-regulate and entrain each other, and thus affect host health and immune-mediated diseases. Here, we systematically review the curre...
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Open AccessAssociation of cognitive impairment and diabetes on survival in Chinese older people with hypertension: a 10-year prospective study
Older people with hypertension may have more complex multisystem problems and a higher risk of morbidity and mortality. We aimed to examine the association of cognitive impairment (CI) and diabetes mellitus (D...
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Open AccessPuerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier
More and more evidence suggests that puerarin, a potential remedy for gut inflammation, may have an ameliorative effect on sleep disturbances. However, the relationship between puerarin and sleep disruption ha...
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Article
Can you notice my attention? A novel information vision enhancement method in MR remote collaborative assembly
In mixed reality (MR) remote collaborative assembly, remote experts can guide local users to complete the assembly of physical tasks by sharing user cues (eye gazes, gestures, etc.) and spatial visual cues (su...
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Open AccessDeterminants on urinary excretion of oxalate and other key factors related to urolithiasis among patients with chronic kidney disease: a single center study
Urolithiasis is a known risk factor for chronic kidney disease (CKD). However, how CKD might affect the risk of incidence of urolithiasis is not widely studied.
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Open AccessComparison of the lower limit of normal to the fixed ratio method for the diagnosis of airflow obstruction at high altitudes: a large cross-sectional survey of subjects living between 3000–4700 m above sea level
There is no general agreement on the preferential use of a fixed ratio (FR) of forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) < 0.7 vs. the lower limit of normal (LLN) of FEV1/FVC to define ai...
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Open AccessStudy on anti-crack effect of semi-rigid base pavement with stress absorbing layer
For the characteristics of semi-rigid base asphalt pavement prone to cracking, various stress-absorption layers are applied widely by decreasing stress concentration, improving interlayer bonding and waterproo...
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Open AccessPolychromatic full-polarization control in mid-infrared light
Objects with different shapes, materials and temperatures can emit distinct polarizations and spectral information in mid-infrared band, which provides a unique signature in the transparent window for object i...
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Open AccessOxycodone vs. tramadol in postoperative parent-controlled intravenous analgesia in children: a prospective, randomized, double-blinded, multiple-center clinical trial
Management of acute postoperative pain is one of the major challenges in pediatric patients. Oral oxycodone has shown good pain relief in postoperative pain relief in children, but no studies have investigated...
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Open AccessDifferent responses of Japanese encephalitis to weather variables among eight climate subtypes in Gansu, China, 2005–2019
This study evaluated epidemic temporal aspects of Japanese encephalitis (JE) and investigated the weather threshold of JE response across eight climate subtypes between 2005 and 2019 in Gansu Province, China. ...
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Open AccessCD47 antisense oligonucleotide treatment attenuates obesity and its-associated metabolic dysfunction
Previous study from our lab has revealed a new role of CD47 in regulating adipose tissue function, energy homeostasis and the development of obesity and metabolic disease in CD47 deficient mice. In this study,...
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Open AccessAll-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RARα-Nrf2 complex
Decitabine (DAC) is used as the first-line therapy in patients with higher-risk myelodysplastic syndromes (HR-MDS) and elderly acute myeloid leukaemia (AML) patients unsuitable for intensive chemotherapy. Howe...