23 Result(s)
within
**usheng Lu
English
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Article
Open AccessThe ufmylation modification of ribosomal protein L10 in the development of pancreatic adenocarcinoma
Pancreatic adenocarcinoma (PAAD) is the most malignant cancer with a high mortality rate. Despite the association of ribosomal protein L10 (RPL10) with PAAD and previous reports on RPL26 ufmylation, the relati...
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Open AccessCancer metastasis chemoprevention prevents circulating tumour cells from germination
The war against cancer traces back to the signature event half-a-century ago when the US National Cancer Act was signed into law. The cancer crusade costs trillions with disappointing returns, teasing the poss...
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Open AccessCorrection to: Embedding similarities between embryos and circulating tumor cells: fundamentals of abortifacients used for cancer metastasis chemoprevention
An amendment to this paper has been published and can be accessed via the original article.
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Open AccessNOL7 facilitates melanoma progression and metastasis
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Open AccessEmbedding similarities between embryos and circulating tumor cells: fundamentals of abortifacients used for cancer metastasis chemoprevention
The global epidemiological studies reported lower cancer risk after long-term use of contraceptives. Our systematic studies demonstrated that abortifacients are effective in preventing cancer metastases induce...
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Open AccessCorrection to: Drain fluid amylase as a predictor of postoperative salivary fistula in cases with benign parotid tumours
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Open AccessClinical application of thioredoxin reductase as a novel biomarker in liver cancer
Hepatic cancer is often amenable to surgery, including percutaneous ablation, trans-arterial chemoembolization. However, in metastatic cases, surgery is often not an effective option. Chemotherapy as a convent...
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Open AccessAuthor Correction: Achyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessAchyranthes bidentata polysaccharide can safely prevent NSCLC metastasis via targeting EGFR and EMT
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Open AccessDrain fluid amylase as a predictor of postoperative salivary fistula in cases with benign parotid tumours
Late diagnosis of a salivary fistula increases the risk of wound infection and scarring. The purpose of the present study was to identify a quantitative predictor of postoperative salivary fistula for cases tr...
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Open AccessPublisher Correction: Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessA novel IFNα-induced long noncoding RNA negatively regulates immunosuppression by interrupting H3K27 acetylation in head and neck squamous cell carcinoma
Interferon alpha (IFNα) is a well-established regulator of immunosuppression in head and neck squamous cell carcinoma (HNSCC), while the role of long noncoding RNAs (lncRNAs) in immunosuppression remains large...
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Open AccessEliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles
There are disease-causing biohazards in the blood that cannot be treated with modern medicines. Here we show that an intelligently designed safe biomaterial can precisely identify, tow and dump a targeted bioh...
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Open AccessFunctionalized MoS2-erlotinib produces hyperthermia under NIR
Molybdenum disulfide (MoS2) has been widely explored for biomedical applications due to its brilliant photothermal conversion ability. In this paper, we report a novel multifunctional MoS2-based drug delivery sys...
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Open AccessDual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells
Carcinoma metastasis is triggered by a subpopulation of circulating tumor cells (CTCs). And single immune checkpoint therapy is not good enough to inhibit CTC-induced metastasis. Here, we demonstrate that simu...
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Open AccessSex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite)
Metapristone is the primary metabolite of the abortifacient mifepristone (RU486), and is being developed as a safe and effective cancer metastatic chemopreventive agent for both sexes. Here, we systematically ...
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Open AccessSuccessful management of rare gingival metastasis from gastric adenocarcinoma: a case report and literature review
Gastric cancer rarely metastasizes to the oral cavity, especially to gingiva. Only 18 cases have been reported worldwide to date. This paper herein presents the nineteenth case of gingival metastasis from gast...
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Open AccessPharmacoproteomic analysis reveals that metapristone (RU486 metabolite) intervenes E-cadherin and vimentin to realize cancer metastasis chemoprevention
Metapristone is the most predominant biological active metabolite of mifepristone and being developed as a novel cancer metastasis chemopreventive agent by us. Despite its prominent metastasis chemopreventive ...
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Open AccessMultivalent Conjugation of Antibody to Dendrimers for the Enhanced Capture and Regulation on Colon Cancer Cells
Circulation tumor cells (CTCs) in the bloodstream of early-stage cancer patients carry the important information about valuable biomarkers and biological properties of primary tumor. However, detection and cap...
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Open AccessExploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial
Cancer metastasis caused by circulating tumor cells (CTCs) accounts for 90% cancer-related death worldwide. Blocking the circulation of CTCs in bloodstream and their hetero-adhesion to vascular endothelia of t...
