13 Result(s)
within
**uqin Pan
Biomedicine
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Article
Open AccessIdentification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning
Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of C...
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Open AccessA hypoxia–glycolysis–lactate-related gene signature for prognosis prediction in hepatocellular carcinoma
Liver cancer ranks sixth in incidence and third in mortality globally and hepatocellular carcinoma (HCC) accounts for 90% of it. Hypoxia, glycolysis, and lactate metabolism have been found to regulate the prog...
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Article
Open AccessMETTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer
Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14(METTL14), a major RNA N6-adenosine methyltran...
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Open AccessLncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2
Emerging studies suggest that long non-coding RNAs (lncRNAs) play crucial roles in colorectal cancer (CRC). Here, we report a lncRNA, SATB2-AS1, which is specifically expressed in colorectal tissue and is sign...
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Open AccessPolymorphisms of TGFBR1, TLR4 are associated with prognosis of gastric cancer in a Chinese population
Helicobacter pylori (H. pylori)-induced gastric cancer is an intricate progression of immune response against H. pylori infection. IL-16, TGF-β1 and TLR4 pathways were the mediators involved in the immune respons...
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Open AccessThe pro-metastasis effect of circANKS1B in breast cancer
Recent studies indicate that circular RNA (circRNA) plays a pivotal role in cancer progression. Here, we sought to investigate its role in breast cancer.
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Open AccessThe long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p
Mounting evidence demonstrates that long noncoding RNAs (lncRNAs) have critical roles during the initiation and progression of cancers. In this study, we report that the small nucleolar RNA host gene 1 (SNHG1)...
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Article
Circulating miR-148/152 family as potential biomarkers in hepatocellular carcinoma
Aberrant expressions of the miR-148/152 family (miR-148a, miR-148b, and miR-152) have been documented in many tumor tissues, including hepatocellular carcinoma (HCC). However, the expression pattern and clinic...
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Article
Associations of polymorphisms in microRNAs with female breast cancer risk in Chinese population
Polymorphisms in microRNA (miRNA) have been discussed to be associated with breast cancer risk; however, the conclusions were always inconsistent in different ethnicities. This case–control study enrolled 450 ...
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Open AccessPrognostic value of pre-operative inflammatory response biomarkers in gastric cancer patients and the construction of a predictive model
Inflammation plays an integral role in carcinogenesis and tumor progression. Inflammatory response biomarkers have shown to be promising prognostic factors for improving the predictive accuracy in various canc...
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The diplotype Fas −1377A/−670G as a genetic marker to predict a lower risk of breast cancer in Chinese women
This study was designed to reveal the effects of Fas and FasL polymorphisms of interest on breast cancer risk. A total of 439 patients with breast cancer and 439 controls were enrolled in this study. The genotype...
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Systematic review and meta-analysis on vitamin D receptor polymorphisms and cancer risk
The vitamin D receptor (VDR) can influence cancer susceptibility through binding to vitamin D. However, the previous studies were contradictory. Therefore this meta-analysis was conducted to clarify the associ...
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Open AccessEffects of genetic variations in the Adiponectin pathway genes on the risk of colorectal cancer in the Chinese population
Decreased expression of adiponectin (ADIPOQ) is associated with an increased risk for develo** colorectal cancer (CRC) in humans. This study was designed to determine whether polymorphisms present in the ADIPOQ
