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  1. Article

    Open Access

    Identification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning

    Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of C...

    Shangshang Hu, Qianni **ao, Rui Gao, Jian Qin, Junjie Nie, Yuhan Chen in BMC Cancer (2024)

  2. Article

    Open Access

    METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer

    Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14(METTL14), a major RNA N6-adenosine methyltran...

    **aoxiang Chen, Mu Xu, Xueni Xu, Kaixuan Zeng, **angxiang Liu, Bei Pan in Molecular Cancer (2020)

  3. Article

    Open Access

    LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2

    Emerging studies suggest that long non-coding RNAs (lncRNAs) play crucial roles in colorectal cancer (CRC). Here, we report a lncRNA, SATB2-AS1, which is specifically expressed in colorectal tissue and is sign...

    Mu Xu, Xueni Xu, Bei Pan, **aoxiang Chen, Kang Lin, Kaixuan Zeng in Molecular Cancer (2019)

  4. Article

    Open Access

    The pro-metastasis effect of circANKS1B in breast cancer

    Recent studies indicate that circular RNA (circRNA) plays a pivotal role in cancer progression. Here, we sought to investigate its role in breast cancer.

    Kaixuan Zeng, Bangshun He, Burton B. Yang, Tao Xu, **aoxiang Chen in Molecular Cancer (2018)

  5. Article

    Open Access

    The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p

    Mounting evidence demonstrates that long noncoding RNAs (lncRNAs) have critical roles during the initiation and progression of cancers. In this study, we report that the small nucleolar RNA host gene 1 (SNHG1)...

    Mu Xu, **aoxiang Chen, Kang Lin, Kaixuan Zeng, **angxiang Liu, Bei Pan in Molecular Cancer (2018)