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Article
Open AccessThe association of SOD and HsCRP with the efficacy of sulforaphane in schizophrenia patients with residual negative symptoms
Emerging evidence indicates a connection between oxidative stress, immune-inflammatory processes, and the negative symptoms of schizophrenia. In addition to possessing potent antioxidant and anti-inflammatory ...
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Article
Multi-stage few-shot micro-defect detection of patterned OLED panel using defect inpainting and multi-scale Siamese neural network
Automatic micro-defect detection is crucial for promoting efficiency in the production lines of patterned OLED panels. Recently, deep learning algorithms have emerged as promising solutions for micro-defect de...
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Article
Open AccessLarge-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults
The genetic contribution of protein-coding variants to immune-mediated diseases (IMDs) remains underexplored. Through whole exome sequencing of 40 IMDs in 350,770 UK Biobank participants, we identified 162 uni...
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Article
Open AccessWhole exome sequencing analysis identifies genes for alcohol consumption
Alcohol consumption is a heritable behavior seriously endangers human health. However, genetic studies on alcohol consumption primarily focuses on common variants, while insights from rare coding variants are ...
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Article
Open AccessCarbon materials in current zinc ion energy storage devices towards sustainability
Emerging energy storage devices are vital approaches towards peak carbon dioxide emissions. Zinc-ion energy storage devices (ZESDs), including zinc ion capacitors and zinc ion batteries, are being intensely pu...
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Article
Open AccessPsychosocial factors affect the occurrence of nonsuicidal self-injury in adolescents with major depressive disorder through chain mediation
In the adolescent group, about half of adolescents with major depressive disorder (MDD) have NSSI. Psychosocial factors are associated with the development of NSSI. Clarifying the relationship between psychoso...
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Article
Correction: DC-PSENet: a novel scene text detection method integrating double ResNet-based and changed channels recursive feature pyramid
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Article
Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with Asian SLE patients
Systemic lupus erythematosus (SLE) is a common autoimmune disease with a polymorphic clinical presentation involving multisystem damages with significant differences in prevalence and disease severity among di...
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Article
Open AccessReallocating just 10 min to moderate-to-vigorous physical activity from other components of 24-hour movement behaviors improves cardiovascular health in adults
As components of a 24-hour day, sedentary behavior (SB), physical activity (PA), and sleep are all independently linked to cardiovascular health (CVH). However, insufficient understanding of components’ mutual...
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Article
Open AccessWhole-exome sequencing identifies protein-coding variants associated with brain iron in 29,828 individuals
Iron plays a fundamental role in multiple brain disorders. However, the genetic underpinnings of brain iron and its implications for these disorders are still lacking. Here, we conduct an exome-wide associatio...
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Article
Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank
Suicide is a global public health challenge, yet considerable uncertainty remains regarding the associations of both behaviour-related and physiological factors with suicide attempts (SA). Here we first estima...
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Article
Investigation of Diameter Regulated SnS2 Nanotube for Photocatalytic Activity: A Hybrid Density Functional Calculation
To explore the potential photocatalytic performance of SnS2 nanotube, we have employed density functional theory (DFT) to predict the photocatalytic performance of SnS2 single-walled nanotubes with HSE06 as excha...
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Article
Open AccessThe predictive value of GLIM criteria on clinical outcomes and responses to nutritional support in patients with neurocritical illnesses
Neurocritically ill patients frequently exhibit coma, gastroparesis, and intense catabolism, leading to an increased risk of malnutrition. The Global Leadership Initiative on Malnutrition (GLIM) criteria for t...
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Article
Open AccessLnc-HIBADH-4 Regulates Autophagy-Lysosome Pathway in Amyotrophic Lateral Sclerosis by Targeting Cathepsin D
Amyotrophic lateral sclerosis (ALS) is the most prevalent and lethal class of severe motor neuron diseases (MND) with no efficacious treatment. The pathogenic mechanisms underlying ALS remain unclear. Nearly 9...
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Article
The key role of myostatin b in somatic growth in fishes derived from distant hybridization
The basic mechanism of heterosis has not been systematically and completely characterized. In previous studies, we obtained three economically important fishes that exhibit rapid growth, WR (WCC ♀ × RCC ♂), WR...
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Article
Open AccessClinical efficacy and identification of factors confer resistance to afatinib (tyrosine kinase inhibitor) in EGFR-overexpressing esophageal squamous cell carcinoma
Epidermal growth factor receptor (EGFR) is reportedly overexpressed in most esophageal squamous cell carcinoma (ESCC) patients, but anti-EGFR treatments offer limited survival benefits. Our preclinical data sh...
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Article
Impact of dose volume parameters and clinical characteristics on radiation-induced acute oral mucositis for head and neck cancer patients treated with carbon-ion radiotherapy dose volume outcome analysis
To assess the predictive value of different dosimetric parameters for acute radiation oral mucositis (ROM) in head and neck cancer (HNCs) patients treated with carbon-ion radiotherapy (CIRT).
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Article
Highly efficient degradation of tetracycline in groundwater by nanoscale zero-valent iron-copper bimetallic biochar: active [H] attack and direct electron transfer mechanism
Development of carbon materials with high activity was important for rapid degradation of emerging pollutants. In this paper, a novel nanoscale zero-valent iron-copper bimetallic biochar (nZVIC-BC) was synthes...
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Article
Assessment of irrigation efficiency for arid-zone spring wheat production under flood irrigation
Understanding the availability of irrigation water at various growth stages is crucial for guiding agricultural scheduling in arid areas with limited water sources. However, challenges persist in swiftly and s...
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Article
Open AccessCSTF3 contributes to platinum resistance in ovarian cancer through alternative polyadenylation of lncRNA NEAT1 and generating the short isoform NEAT1_1
Platinum-based chemotherapy is the standard postoperative adjuvant treatment for ovarian cancer (OC). Despite the initial response to chemotherapy, 85% of advanced OC patients will have recurrent disease. Rela...
