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12 Result(s)

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  1. Article

    Open Access

    Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer

    APE1 is an essential gene involved in DNA damage repair, the redox regulation of transcriptional factors (TFs) and RNA processing. APE1 overexpression is common in cancers and correlates with poor patient surv...

    Shuyu Mao, Chong **e, Yufeng Liu, Ye Zhao… in Cellular and Molecular Life Sciences (2024)

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  2. No Access

    Article

    GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis

    Radioresistance is the primary reason for radiotherapy failure in non-small cell lung cancer (NSCLC) patients. Glycosylation-related alterations are critically involved in tumor radioresistance. However, the r...

    **aoxia Dong, Yahui Leng, Tian Tian, Qing Hu, Shuang Chen… in Cell Biology and Toxicology (2023)

  3. Article

    Open Access

    4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer

    Nutrient-limiting conditions are common during cancer development. The coordination of cellular glucose levels and cell survival is a fundamental question in cell biology and has not been completely understood...

    Yanan Wang, Jiapeng Lei, Song Zhang, **aomei Wang, Jiangbo **… in Cell Death & Disease (2022)

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  4. Article

    Open Access

    Cytochrome B5 type A alleviates HCC metastasis via regulating STOML2 related autophagy and promoting sensitivity to ruxolitinib

    The incidence of hepatocellular carcinoma (HCC) is increasing in the world. However, its role and underlying molecular mechanism in HCC progression remain unclear. We found that CYB5A plays a key role in HCC m...

    Hongrui Guo, Shuhang Liang, Yan Wang, Shuo Zhou, Dalong Yin… in Cell Death & Disease (2022)

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  5. No Access

    Article

    Identification and characterization of methyltransferases involved in benzylisoquinoline alkaloids biosynthesis from Stephania intermedia

    To characterize methyltransferases involved in the biosynthesis of benzylisoquinoline alkaloids in Stephania intermedia.

    Wanli Zhao, Chen Shen, **qian Zhu, Chenhui Ou, Manyu Liu… in Biotechnology Letters (2020)

  6. Article

    Open Access

    Novel dihydroartemisinin derivative DHA-37 induces autophagic cell death through upregulation of HMGB1 in A549 cells

    Dihydroartemisinin (DHA) and its analogs are reported to possess selective anticancer activity. Here, we reported a novel DHA derivative DHA-37 that exhibited more potent anticancer activity on the cells teste...

    **ufeng Liu, Juanjuan Wu, Menglin Fan, Chen Shen, Wenling Dai… in Cell Death & Disease (2018)

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  7. No Access

    Article

    Combined sense-antisense Alu elements activate the EGFP reporter gene when stable transfection

    Alu elements in the human genome are present in more than one million copies, accounting for 10% of the genome. However, the biological functions of most Alu repeats are unknown. In this present study, we dete...

    Zhihong Ma, **anglong Kong, Shufeng Liu, Shuxian Yin… in Molecular Genetics and Genomics (2017)

  8. No Access

    Article

    Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols

    To characterize glycosyltransferases from Bacillus subtilis ATCC 6633 and investigate their substrate specificity towards plant polyphenols.

    Qianqian Wang, Yixiang Xu, Jiaqi Xu, Xudong Wang, Chen Shen… in Biotechnology Letters (2017)

  9. No Access

    Article

    Nano-TiO2 Improve the Photosynthesis of Tomato Leaves under Mild Heat Stress

    Nano-TiO2 has been reported to promote photosynthesis in some crops; however, the mechanism behind this action remains unknown. In this research, the effects of nano-TiO2 on leaf photosynthesis under mild heat st...

    Mingfang Qi, Yufeng Liu, Tianlai Li in Biological Trace Element Research (2013)

  10. No Access

    Article

    Lithium enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells

    Non-small cell lung cancer (NSCLC) A549 cells are resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Therefore, combination therapy using sensitizing agents to over...

    Yan Lan, **ufeng Liu, Rong Zhang, Kai Wang, Yao Wang, Zi-Chun Hua in BioMetals (2013)

  11. No Access

    Article

    Effect of RNAi-induced down regulation of nuclear factor kappa-B p65 on acute monocytic leukemia THP-1 cells in vitro and vivo

    NF-κB p65 is found constitutively active in acute monocytic leukemia, and has been considered an important factor for poor prognosis. Therefore, develop specifically target p65 inhibitors will be substantial i...

    Chunmei Wang, Guangyao Sheng, Jie Lu, Lei **e… in Molecular and Cellular Biochemistry (2012)

  12. Article

    DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein

    The zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses by eliminating viral mRNAs in the cytoplasm. In previous studies, we demonstrated that ZAP...

    Peiying Ye, Shufeng Liu, Yi** Zhu, Guifang Chen, Guangxia Gao in Protein & Cell (2010)

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