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  1. Article

    Open Access

    Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning

    The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.

    Guang-Yu Ding, Wei-Min Tan, You-Pei Lin, Yu Ling, Wen Huang, Shu Zhang in BMC Medicine (2024)

  2. Article

    Open Access

    Signal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma

    To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference stan...

    Cong **a, **-rong Qu, Yi-** Jiao, Chun-qiang Lu, Ben Zhao in European Radiology (2024)

  3. No Access

    Article

    Clinical application of repetitive transcranial magnetic stimulation in improving functional impairments post-stroke: review of the current evidence and potential challenges

    In recent years, the stroke incidence has been increasing year by year, and the related sequelae after stroke, such as cognitive impairment, motor dysfunction, and post-stroke depression, seriously affect the ...

    Ming Cai, Jia-ling Zhang, **ao-jun Wang, Ke-ren Cai, Shu-yao Li in Neurological Sciences (2024)

  4. Article

    Open Access

    Comprehensive assessment of fine motor movement and cognitive function among older adults in China: a cross-sectional study

    Fine motor skills are closely related to cognitive function. However, there is currently no comprehensive assessment of fine motor movement and how it corresponds with cognitive function. To conduct a complete...

    Jie Zhang, Ye-**g Zhao, Jun-Yi Wang, Han Cui, Shaojie Li, Xue Meng in BMC Geriatrics (2024)

  5. Article

    Open Access

    Development and evaluation of short-form version of the Constitution in Chinese Medicine Questionnaire: study a new and best brief instrument of Chinese medicine for health management

    More efficient instruments for body constitution identification are needed for clinical practice. We aimed to develop the short-form version of the Constitution in Chinese Medicine Questionnaire (CCMQ) and eva...

    Ming-Hua Bai, Zhu-Qing Li, Huai-Yu Wang, **ao-Li Ma, Zhong-Li Wang in Chinese Medicine (2023)

  6. Article

    Open Access

    The efficacy and safety of apatinib plus capecitabine in platinum-refractory metastatic and/or recurrent nasopharyngeal carcinoma: a prospective, phase II trial

    Previous studies have shown that monotherapy with apatinib, an oral tyrosine kinase inhibitor, has promising efficacy for treating recurrent or metastatic (RM) nasopharyngeal carcinoma (NPC) patients. In this ...

    Lin-Quan Tang, **ao-Yun Li, Zhi-Ming Li, Zhi-Gang Liu, Miao-Zhen Lin in BMC Medicine (2023)

  7. Article

    Open Access

    Insulin resistance in women with recurrent miscarriage: a systematic review and meta-analysis

    This review aimed to investigate the association of insulin resistance (IR) in women with recurrent pregnancy loss compared to women with normal pregnancy history.

    Wang-Yu Cai, ** Luo, Hou-Yi Lv, Kai-You Fu, Jian Xu in BMC Pregnancy and Childbirth (2022)

  8. No Access

    Article

    Naoxintong Capsule for Secondary Prevention of Ischemic Stroke: A Multicenter, Randomized, and Placebo-Controlled Trial

    To examine whether the combination of Naoxintong Capsule with standard care could further reduce the recurrence of ischemic stroke without increasing the risk of severe bleeding.

    **ao-fei Yu, Xu-ying Zhu, Can-xing Yuan in Chinese Journal of Integrative Medicine (2022)

  9. Article

    Open Access

    Systemic immune inflammation index and system inflammation response index are potential biomarkers of atrial fibrillation among the patients presenting with ischemic stroke

    Chronic inflammatory disorders in atrial fibrillation (AF) contribute to the onset of ischemic stroke. Systemic immune inflammation index (SIII) and system inflammation response index (SIRI) are the two novel ...

    Kai-bin Lin, Feng-hua Fan, Ming-qi Cai, Yin Yu in European Journal of Medical Research (2022)

  10. Article

    Open Access

    Applications of mPCR testing reduced initial antibiotic use and duration of mechanical ventilation in virus-infected children with severe community-acquired pneumonia admitted to the PICU

    Chao-Nan Fan, Bo-Liang Fang, Heng-Miao Gao, Ru-Bo Li in World Journal of Pediatrics (2022)

  11. No Access

    Article

    Multidimensional fatigue in patients with nasopharyngeal carcinoma receiving concurrent chemoradiotherapy: incidence, severity, and risk factors

    To explore the incidence, severity, and risk factors of multidimensional fatigue in patients with nasopharyngeal carcinoma (NPC) receiving concurrent chemoradiotherapy (CCRT).

    Lin-Min Chen, Qiu-Lan Yang, Yu-Yu Duan, Xue-Zhen Huan, Yan He in Supportive Care in Cancer (2021)

  12. Article

    Open Access

    Bilateral pulmonary embolism without deep venous thrombosis was observed after knee arthroscopy: a case report

    Symptomatic pulmonary embolism (PE) after knee arthroscopy is extremely rare. If the embolism is not treated promptly, the patient may die. Bilateral pulmonary embolism with associated pulmonary infarct withou...

    Yuan Li, You-**a Chen, **ang-Tian Deng, Shun-cheng Yang in BMC Musculoskeletal Disorders (2021)

  13. Article

    Open Access

    Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline (updated version)

    The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the ...

    Ying-Hui **, Qing-Yuan Zhan, Zhi-Yong Peng, Xue-Qun Ren in Military Medical Research (2020)

  14. Article

    Correction to: Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model

    In the article that appeared on Page: 341-348, Vol 23 (15 September 2018) of the Sleep and breathing [1], one error was discovered in Figure 3. The picture of Normoxia and CIH in 100X is the same one. The correct...

    **ao-Bin Zhang, **g-Huang Cai, Yu-Yun Yang, Yi-Ming Zeng in Sleep and Breathing (2020)

  15. No Access

    Article

    A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study

    We aimed to establish a discriminative gene-expression-based classifier to predict survival outcomes of T-cell lymphoblastic lymphoma (T-LBL) patients. After exploring global gene-expression profiles of progre...

    **ao-Peng Tian, Dan **e, Wei-Juan Huang, Shu-Yun Ma, Liang Wang, Yan-Hui Liu in Leukemia (2020)

  16. No Access

    Article

    Decreased plasma riboflavin is associated with poor prognosis, invasion, and metastasis in esophageal squamous cell carcinoma

    Riboflavin deficiency confers a predisposition for esophageal cancer. The role of plasma riboflavin levels in development and prognosis of individuals with digestive tract inflammation and ulcer (DTIU), digest...

    Feng Pan, Hong-Jun Luo, Zhi-Yong Wu, Su-Zuan Chen in European Journal of Clinical Nutrition (2020)

  17. No Access

    Article

    Upfront autologous stem cell transplantation for untreated diffuse large B cell lymphoma patients in rituximab era: a systematic review and meta-analysis

    To assess the survival outcomes and adverse events (AEs) of high-intermediate- or high-risk patients with diffuse large B cell lymphoma (DLBCL) who underwent conventional chemotherapy plus rituximab with or wi...

    Shu-Yun Ma, **ao-Peng Tian, Jun Cai, Guang-Zheng Zhong, Xu Chen in Annals of Hematology (2020)

  18. Article

    Open Access

    Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model

    Obstructive sleep apnea (OSA) is associated with renal impairs. As a novel pathophysiological hallmark of OSA, chronic intermittent hypoxia (CIH) enhances apoptosis and autophagy. The present study aims to eva...

    **ao-Bin Zhang, **g-Huang Cai, Yu-Yun Yang, Yi-Ming Zeng in Sleep and Breathing (2019)

  19. Article

    Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition)

    Hand, foot, and mouth disease (HFMD) is a common infectious disease in childhood caused by an enterovirus (EV), and which is principally seen in children under 5 years of age. To promote diagnostic awareness a...

    **ng-Wang Li, **n Ni, Su-Yun Qian, Quan Wang in World Journal of Pediatrics (2018)

  20. Article

    Chinese guidelines for the assessment and provision of nutrition support therapy in critically ill children

    This document represents the first evidence-based guidelines to describe best practices in nutrition therapy in critically ill children (> 1 month and < 18 years), who are expected to require a length of stay ...

    Xue-Mei Zhu, Su-Yun Qian, Guo-** Lu, Feng Xu, Ying Wang in World Journal of Pediatrics (2018)

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