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  1. Article

    Open Access

    Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning

    The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.

    Guang-Yu Ding, Wei-Min Tan, You-Pei Lin, Yu Ling, Wen Huang, Shu Zhang in BMC Medicine (2024)

  2. Article

    Open Access

    The efficacy and safety of apatinib plus capecitabine in platinum-refractory metastatic and/or recurrent nasopharyngeal carcinoma: a prospective, phase II trial

    Previous studies have shown that monotherapy with apatinib, an oral tyrosine kinase inhibitor, has promising efficacy for treating recurrent or metastatic (RM) nasopharyngeal carcinoma (NPC) patients. In this ...

    Lin-Quan Tang, **ao-Yun Li, Zhi-Ming Li, Zhi-Gang Liu, Miao-Zhen Lin in BMC Medicine (2023)

  3. No Access

    Article

    Naoxintong Capsule for Secondary Prevention of Ischemic Stroke: A Multicenter, Randomized, and Placebo-Controlled Trial

    To examine whether the combination of Naoxintong Capsule with standard care could further reduce the recurrence of ischemic stroke without increasing the risk of severe bleeding.

    **ao-fei Yu, Xu-ying Zhu, Can-xing Yuan in Chinese Journal of Integrative Medicine (2022)

  4. Article

    Open Access

    Systemic immune inflammation index and system inflammation response index are potential biomarkers of atrial fibrillation among the patients presenting with ischemic stroke

    Chronic inflammatory disorders in atrial fibrillation (AF) contribute to the onset of ischemic stroke. Systemic immune inflammation index (SIII) and system inflammation response index (SIRI) are the two novel ...

    Kai-bin Lin, Feng-hua Fan, Ming-qi Cai, Yin Yu in European Journal of Medical Research (2022)

  5. No Access

    Article

    A gene-expression-based signature predicts survival in adults with T-cell lymphoblastic lymphoma: a multicenter study

    We aimed to establish a discriminative gene-expression-based classifier to predict survival outcomes of T-cell lymphoblastic lymphoma (T-LBL) patients. After exploring global gene-expression profiles of progre...

    **ao-Peng Tian, Dan **e, Wei-Juan Huang, Shu-Yun Ma, Liang Wang, Yan-Hui Liu in Leukemia (2020)

  6. No Access

    Article

    Decreased plasma riboflavin is associated with poor prognosis, invasion, and metastasis in esophageal squamous cell carcinoma

    Riboflavin deficiency confers a predisposition for esophageal cancer. The role of plasma riboflavin levels in development and prognosis of individuals with digestive tract inflammation and ulcer (DTIU), digest...

    Feng Pan, Hong-Jun Luo, Zhi-Yong Wu, Su-Zuan Chen in European Journal of Clinical Nutrition (2020)

  7. No Access

    Article

    Neuroprotective Effects of Electroacupuncture Preventive Treatment in Senescence-Accelerated Mouse Prone 8 Mice

    To investigate the preventive treatment effects of electroacupuncture (EA) on cognitive changes and brain damage in senescence-accelerated mouse prone 8 (SAMP8) mice.

    **ao-li He, Shi-hui Zhao, Wei You, Yu-ying Cai in Chinese Journal of Integrative Medicine (2018)

  8. Article

    Open Access

    Use acupuncture to treat functional constipation: study protocol for a randomized controlled trial

    Whether acupuncture is effective for patients with functional constipation is still unclear. Therefore, we report the protocol of a randomized controlled trial of using acupuncture to treat functional constipa...

    Ying Li, Hui Zheng, Fang Zeng, Si-yuan Zhou, Feng Zhong, Hua-bing Zheng, Min Chen in Trials (2012)

  9. No Access

    Article

    Three isoforms of annexin I are preferentially expressed in normal esophageal epithelia but down-regulated in esophageal squamous cell carcinomas

    The development and progression of human cancer are believed to be due to the alterations of multiple genes or/and their protein products. For identifying the proteins associated with esophageal cancer, we ana...

    Shu-Hua **a, Li-** Hu, Hai Hu, Wan-Tao Ying, **n Xu, Yan Cai, Ya-Ling Han in Oncogene (2002)