1,082 Result(s)

Article

Translocation chromosome 7 of A431 cells contains amplification and rearrangement of EGF receptor gene responsible for production of variant mRNA

The epidermal growth factor (EGF) receptor, along with several oncogene protein products, possesses tyrosine-specific protein kinase activity. Furthermore, the EGF receptor has structural similarity to the put.....

John H. Hunts, Nobuyoshi Shimizu, Tadashi Yamamoto… in Somatic Cell and Molecular Genetics (1985)

Article

X-ray diffraction studies of the structural state of crossbridges in skinned frog sartorius muscle at low ionic strength

Low-angle X-ray diffraction diagrams were obtained from chemically skinned frog sartorius muscles under low ionic strength relaxing conditions. Experiments on single muscle fibres from rabbit muscle and on mus...

Sengen Xu, M. Kress, H. E. Huxley in Journal of Muscle Research & Cell Motility (1987)

Article

Molecular analysis of human repetitive sequence family and its use as genetic marker

Martha Liao Law, Yisheng Xu, Ralph Berger, Lin Tung in Somatic Cell and Molecular Genetics (1987)

Article

Replication-dependent mutagenesis by 5-bromodeoxyuridine: Identification of base change and sequence effects on mutability

The moleeular mechanism of reversion induced by 5-bromodeoxyuridine (BrdU) replication-dependent mutagenesis in mammalian cells was studied. Murine cells with single mutant copies of theE. coli gpt gene integrate...

Faming Xu, Jeffrey A. Greenspan, Richard L. Davidson in Somatic Cell and Molecular Genetics (1990)

Chapter

²¹⁰Pb Chronologies of Recent Sediments in Tidal Lakes of the Chenier Marshes of Louisiana

The chenier marshes of southwestern Louisiana which adjoin the northern Gulf of Mexico contain many embedded lakes and the higher ridges from which the region derives its name. This region, along with the Miss...

J. R. Meriwether, X. Xu, R. Lee, W. Sheu… in Radionuclides in the Study of Marine Proce… (1991)

Chapter

Epigenetic Features of Spontaneous Transformation in the NIH 3T3 Line of Mouse Cells

There is a longstanding debate in cancer research about the primary cause of malignant cell growth: is cancer the result of genetic events or the outcome of epigenetic processes? The weight of opinion seems to...

H. Rubin, Kang Xu in Boundaries between Promotion and Progression during Carcinogenesis (1991)

Chapter

Reduced Latency of Visually Evoked Potentials Following Cortical Injury Indicates Secondary Glutamatergic Neuronal Excitation

While searching for physiological evidence of secondary hyperexcitability following brain injury (Saito et al., 1990), we observed that the latency of visually evoked responses (VER)s was reduced following a u...

Shichen Xu, Henry G. Wagner, Ferenc Joo… in The Role of Neurotransmitters in Brain Inj… (1992)

Chapter

Multi—Mode Coupling of Protein Motion to Electron Transfer in the Photosynthetic Reaction Center: Spin — Boson Theory Based on a Classical Molecular Dynamics Simulation

We present a quantum mechanical description (spin-boson model) for electron transfer rates in the photosynthetic reaction center of Rh. viridis which assumes for the protein nuclear motion a broad distribution of...

Dong Xu, Klaus Schulten in The Photosynthetic Bacterial Reaction Center II (1992)

Chapter

Streptococcal M Protein: A Common Structural Motif Used by Gram-Positive Bacteria for Biologically Active Surface Molecules

In 1981 when the coiled-coil structure of the M6 protein was determined,¹ it was unique for bacterial surface molecules. Since that time, several other M proteins have been se­quenced as well as a number of other...

V. A. Fischetti, V. Pancholi, P. Sellers… in Molecular Recognition in Host-Parasite Int… (1992)

Article

Immobilization of lipase in composites of gelatin and polystyrene via an emulsion-gel pathway

A new method for the immobilization of lipase within composites of polystyrene and gelatin is suggested. First, an emulsion of styrene (containing an initiator) in an aqueous solution of gelatin (containing a ...

Eli Ruckenstein, Gu Xu in Biotechnology Techniques (1992)

Chapter

Signals Required for Differentiating Dendritic Cells from Human Monocytes in Vitro

Human peripheral blood monocytes (Mo) can quantitatively be differentiated into potent accessory cells which exhibit dendritic cell (DC) function and phenotype. This alternative differentiation of Mo into DC r...

J. Hinrich Peters, Hui Xu, Jörg Ruppert… in Dendritic Cells in Fundamental and Clinica… (1993)

Chapter

Serum-Free Differentiation of Rat and Human Dendritic Cells, Accompanied by Acquisition of the Nuclear Lamins A/C as Differentiation Markers

It is generally accepted that tissue macrophages (Mφ) derive from a common bone marrow (BM) precursor. Clearly, it is the myeloid lineage that branches into the development of Mφ and granulocytes. For contrast...

Robert K. H. Gieseler, Hui Xu… in Dendritic Cells in Fundamental and Clinica… (1993)

Chapter

Distinct T Cell Stimulation Mechanism and Phenotype of Human Blood Dendritic Cells

Dendritic cells (DC) have been found to exist as antigen-presenting cells in nonlymphoid and lymphoid tissues. ^1,2 They play an important role in modulation of the immune reaction. ^3,4 Blood dendritic cells (BDC)...

Hui Xu, Ulrike Friedrichs… in Dendritic Cells in Fundamental and Clinica… (1993)

Chapter

Investigation of Lattice Surface Layers by Scanning Probe Microscopy

Scanning probe microscopy (SPM) is emerging as an important complementary technique to conventional microscopy for high-resolution surface investigation (Wickramasinghe, 1990). In SPM, no lenses are used and t...

Max Firtel, Gordon Southam… in Advances in Bacterial Paracrystalline Surf… (1993)

Chapter

Feline Maternal Taurine Deficiency: Effects on Visual Cortex of the Offspring. A Morphometric and Immunohistochemical Study

Cats are dependent on an adequate dietary source of taurine to maintain their body pools because their endogenous taurine biosynthesis is limited by a low activity of cysteinesulfinic acid decarboxylase (7). W...

John A. Sturman, Peimin Lu, Yue-**ang Xu, Humi Imaki in Taurine in Health and Disease (1994)

Chapter

Signal Transduction During T Cell Development

The CD4 molecule has important roles in signaling during both T cell development and peripheral helper T cell activation^1,2. The ectodomain of CD4 binds to a membrane-proximal domain of MHC class II molecules on ...

Dan R. Littman, Craig B. Davis… in Mechanisms of Lymphocyte Activation and Im… (1994)

Chapter

Genotoxin-Induced Apoptosis: Implications for Carcinogenesis

Apoptosis is thought to be a programmed form of cell death which, when balanced by cell proliferation, contributes to the regulation of tissue homeostasis (1). An imbalance between apoptosis and proliferation ...

Steven R. Patierno, Lori J. Blankenship, John P. Wise, Jian Xu… in The Cell Cycle (1994)

Chapter

Properties of Mitochondrial DNA Metabolising Enzymes; Implications for Chemotherapy

Antiviral chemotherapy against HIV infection is based on the use of dideoxynucleoside analogs such as Zidovudine (3’-azido-deoxythymidine, AZT), dideoxycytidne (ddC) and dideoxyinosine, that are inhibitors of ...

Staffan Eriksson, Baoji Xu… in Purine and Pyrimidine Metabolism in Man VIII (1994)