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**u Xu
Life Sciences
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Article
Correction: Study on vibration performance and comfort of glulam beam and deck floor
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Article
The Role of Histone H2B Acetylation Modification in Aluminum-Induced Cognitive Dysfunction
Aluminum (Al) is a low toxic trace element that can accumulate in the nervous system and induce cognitive disorders characterized by reduced learning and memory ability. Neuroepigenetic effects are structural ...
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Article
Water-Soluble Se-Containing Proteins from Chicken Alleviate DSS-Induced Ulcerative Colitis in Mice via Inhibiting TLR4/MyD88 Pathway and Protecting the Goblet Cell Pathway
The influence of water-soluble selenium-containing proteins (WSSeP) in chicken on ulcerative colitis (UC) is not known. This work aims to investigate the effect of two WSSeP including h-Se with 1.78 μg Se/g an...
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Article
The impact of temperature variations on the thermal and charring characteristics of laminated bamboo lumber
The fire performance of buildings can be assessed through the thermal and charring characteristics of laminated bamboo lumber (LBL), due to its combustibility properties, which are akin to those of wood. This ...
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Article
Study on vibration performance and comfort of glulam beam and deck floor
This paper presents the dynamic characteristics of the glued-laminated-timber (glulam) floor within China's tallest timber office building and establishes a Finite Element (FE) model. The veracity of the FE mo...
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Article
Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice
Premature ovarian insufficiency (POI) is a heterogeneous female disorder characterized by the loss of ovarian function before the age of 40. It represents a significant detriment to female fertility. However, ...
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Erratum to: Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival
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Article
USP13 promotes proliferation and angiogenesis of diffuse large B-cell lymphoma cells by promoting MCL-1 expression
Diffuse large B-cell lymphoma (DLBCL) is a diffuse malignant hyperplastic disease of large B-cell lymphoma characterized by high heterogeneous and aggressiveness and has a poor prognosis.
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Article
Combining use of phillyrin and autophagy blocker exerts suppressive effect on nasopharyngeal carcinoma cell malignancy and autophagy via AMPK/mTOR/p70s6k signaling pathway
Nasopharyngeal carcinoma (NPC) is one of the malignant cancers in southern China. Phillyrin is a major active constituent extracted from Forsythia suspensa (Thunb.) and possesses anti-inflammatory and anti-tumor ...
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Article
Sodium intake: a double-edged sword wielded by the brain
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Article
Open AccessVBP1 promotes tumor proliferation as a part of the hypoxia-related signature in esophageal squamous cell carcinoma
Esophageal squamous cell carcinoma (ESCC) is a common malignant tumor in East Asia. Hypoxia, a hallmark of solid tumors, significantly alters redox homeostasis inside tumor microenvironment. This alteration dr...
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Overcoming genotypic dependency and bypassing immature embryos in wheat transformation by using morphogenic regulators
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The Association Between Dietary Magnesium Intake with Chronic Obstructive Pulmonary Disease and Lung Function in US Population: a Cross-sectional Study
Chronic obstructive pulmonary disease (COPD) is now considered among the top three contributors to mortality globally. There is limited understanding surrounding the contribution of magnesium to the progressio...
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Article
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway
Tissue engineering is increasingly viewed as a promising avenue for functional cartilage reconstruction. However, chondrocyte dedifferentiation during in vitro culture remains an obstacle for clinical translation...
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Responses of non-structural carbohydrate content to different stand densities and configurations in poplar plantations
Non-structural carbohydrate (NSC) reserves constitute the critical cornerstone of forest resilience to adversity and post-disaster recovery. Planting densities and configurations affect the growth and physiolo...
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Open AccessAn ‘activator-repressor’ loop controls the anthocyanin biosynthesis in red-skinned pear
The color of red-skinned pear (Pyrus spp.) is primarily attributed to accumulation of anthocyanins, which provide nutritional benefits for human health and are closely associated with the commercial value of frui...
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Dexmedetomidine promotes autophagy and apoptosis of colon cancer cells by activating endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4 signaling pathway
Colon cancer is a malignancy from digestive tract and remains the third most common cancer worldwide. Dexmedetomidine (DEX) can be used for postoperative analgesia in patients with colon cancer and also has bi...
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AP-1 and SP1 trans-activate the expression of hepatic CYP1A1 and CYP2A6 in the bioactivation of AFB1 in chicken
Dietary exposure to aflatoxin B1 (AFB1) is harmful to the health and performance of domestic animals. The hepatic cytochrome P450s (CYPs), CYP1A1 and CYP2A6, are the primary enzymes responsible for the bioactivat...
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Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
Plant regeneration in the new era: from molecular mechanisms to biotechnology applications
Plants or tissues can be regenerated through various pathways. Like animal regeneration, cell totipotency and pluripotency are the molecular basis of plant regeneration. Detailed systematic studies on Arabidopsis...
