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Open AccessIdentification of missing hierarchical relations in the vaccine ontology using acquired term pairs
The Vaccine Ontology (VO) is a biomedical ontology that standardizes vaccine annotation. Errors in VO will affect a multitude of applications that it is being used in. Quality assurance of VO is imperative to ...
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Article
Open AccessRepresenting vaccine misinformation using ontologies
In this paper, we discuss the design and development of a formal ontology to describe misinformation about vaccines. Vaccine misinformation is one of the drivers leading to vaccine hesitancy in patients. While...
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Open AccessBuilding a semantic web-based metadata repository for facilitating detailed clinical modeling in cancer genome studies
Detailed Clinical Models (DCMs) have been regarded as the basis for retaining computable meaning when data are exchanged between heterogeneous computer systems. To better support clinical cancer data capturing...
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Open AccessModulated evaluation metrics for drug-based ontologies
Research for ontology evaluation is scarce. If biomedical ontological datasets and knowledgebases are to be widely used, there needs to be quality control and evaluation for the content and structure of the on...
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Open AccessOptimization on machine learning based approaches for sentiment analysis on HPV vaccines related tweets
Analysing public opinions on HPV vaccines on social media using machine learning based approaches will help us understand the reasons behind the low vaccine coverage and come up with corresponding strategies t...
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Open AccessTrivalent influenza vaccine adverse symptoms analysis based on MedDRA terminology using VAERS data in 2011
Trivalent Influenza Virus Vaccine (FLU3) is a traditional flu vaccine to protect people against three different flu viruses, including influenza A H1N1 virus, an influenza A H3N2 virus and one B virus.
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Open AccessErratum to: Extracting drug-enzyme relation from literature as evidence for drug drug interaction
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Open AccessExtracting drug-enzyme relation from literature as evidence for drug drug interaction
Information about drug–drug interactions (DDIs) is crucial for computational applications such as pharmacovigilance and drug repurposing. However, existing sources of DDIs have the problems of low coverage, lo...
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Article
Open AccessVaccine and Drug Ontology Studies (VDOS 2014)
The “Vaccine and Drug Ontology Studies” (VDOS) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have been critical to prevent and treat ...
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Open AccessIdentification of sex-associated network patterns in Vaccine-Adverse Event Association Network in VAERS
Vaccines are one of the most important public health successes in last century. Besides effectiveness in reducing the morbidity and mortality from many infectious diseases, a successful vaccine program also re...
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Open AccessDevelo** VISO: Vaccine Information Statement Ontology for patient education
To construct a comprehensive vaccine information ontology that can support personal health information applications using patient-consumer lexicon, and lead to outcomes that can improve patient education.
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Open AccessA use case study on late stent thrombosis for ontology-based temporal reasoning and analysis
In this paper, we show how we have applied the Clinical Narrative Temporal Relation Ontology (CNTRO) and its associated temporal reasoning system (the CNTRO Timeline Library) to trend temporal information with...
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Open AccessNetwork-based analysis reveals distinct association patterns in a semantic MEDLINE-based drug-disease-gene network
A huge amount of associations among different biological entities (e.g., disease, drug, and gene) are scattered in millions of biomedical articles. Systematic analysis of such heterogeneous data can infer nove...
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Open AccessOAE: The Ontology of Adverse Events
A medical intervention is a medical procedure or application intended to relieve or prevent illness or injury. Examples of medical interventions include vaccination and drug administration. After a medical int...
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Open AccessA 2013 workshop: vaccine and drug ontology studies (VDOS 2013)
The 2013 “Vaccine and Drug Ontology Studies” (VDOS 2013) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have contributed to dramatic i...
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Open AccessNetwork-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology
Ontologies are useful in many branches of biomedical research. For instance, in the vaccine domain, the community-based Vaccine Ontology (VO) has been widely used to promote vaccine data standardization, integ...
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Open AccessOntology-based time information representation of vaccine adverse events in VAERS for temporal analysis
The U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) provides a valuable data source for post-vaccination adverse event analyses. The structured data in the system has been widely used, but the info...
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Open AccessA 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012)
Vaccines and drugs have contributed to dramatic improvements in public health worldwide. Over the last decade, there have been efforts in develo** biomedical ontologies that represent various areas associate...