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Multiagent Framework for Bio-data Mining

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  1. Article

    Open Access

    Identification of missing hierarchical relations in the vaccine ontology using acquired term pairs

    The Vaccine Ontology (VO) is a biomedical ontology that standardizes vaccine annotation. Errors in VO will affect a multitude of applications that it is being used in. Quality assurance of VO is imperative to ...

    Warren Manuel, Rashmie Abeysinghe, Yongqun He, Cui Tao in Journal of Biomedical Semantics (2022)

  2. Article

    Open Access

    Representing vaccine misinformation using ontologies

    In this paper, we discuss the design and development of a formal ontology to describe misinformation about vaccines. Vaccine misinformation is one of the drivers leading to vaccine hesitancy in patients. While...

    Muhammad Amith, Cui Tao in Journal of Biomedical Semantics (2018)

  3. Article

    Open Access

    Building a semantic web-based metadata repository for facilitating detailed clinical modeling in cancer genome studies

    Detailed Clinical Models (DCMs) have been regarded as the basis for retaining computable meaning when data are exchanged between heterogeneous computer systems. To better support clinical cancer data capturing...

    Deepak K. Sharma, Harold R. Solbrig, Cui Tao in Journal of Biomedical Semantics (2017)

  4. Article

    Open Access

    Modulated evaluation metrics for drug-based ontologies

    Research for ontology evaluation is scarce. If biomedical ontological datasets and knowledgebases are to be widely used, there needs to be quality control and evaluation for the content and structure of the on...

    Muhammad Amith, Cui Tao in Journal of Biomedical Semantics (2017)

  5. Article

    Open Access

    Optimization on machine learning based approaches for sentiment analysis on HPV vaccines related tweets

    Analysing public opinions on HPV vaccines on social media using machine learning based approaches will help us understand the reasons behind the low vaccine coverage and come up with corresponding strategies t...

    **gcheng Du, Jun Xu, Hsingyi Song, **angyu Liu, Cui Tao in Journal of Biomedical Semantics (2017)

  6. Article

    Open Access

    Trivalent influenza vaccine adverse symptoms analysis based on MedDRA terminology using VAERS data in 2011

    Trivalent Influenza Virus Vaccine (FLU3) is a traditional flu vaccine to protect people against three different flu viruses, including influenza A H1N1 virus, an influenza A H3N2 virus and one B virus.

    **gcheng Du, Yi Cai, Yong Chen, Cui Tao in Journal of Biomedical Semantics (2016)

  7. Article

    Open Access

    Erratum to: Extracting drug-enzyme relation from literature as evidence for drug drug interaction

    Yaoyun Zhang, Heng-Yi Wu, **gcheng Du, Jun Xu in Journal of Biomedical Semantics (2016)

  8. Article

    Open Access

    Extracting drug-enzyme relation from literature as evidence for drug drug interaction

    Information about drug–drug interactions (DDIs) is crucial for computational applications such as pharmacovigilance and drug repurposing. However, existing sources of DDIs have the problems of low coverage, lo...

    Yaoyun Zhang, Heng-Yi Wu, **gcheng Du, Jun Xu in Journal of Biomedical Semantics (2016)

  9. Article

    Open Access

    Vaccine and Drug Ontology Studies (VDOS 2014)

    The “Vaccine and Drug Ontology Studies” (VDOS) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have been critical to prevent and treat ...

    Cui Tao, Yongqun He, Sivaram Arabandi in Journal of Biomedical Semantics (2016)

  10. Article

    Open Access

    Identification of sex-associated network patterns in Vaccine-Adverse Event Association Network in VAERS

    Vaccines are one of the most important public health successes in last century. Besides effectiveness in reducing the morbidity and mortality from many infectious diseases, a successful vaccine program also re...

    Yuji Zhang, Puqiang Wu, Yi Luo, Cui Tao in Journal of Biomedical Semantics (2015)

  11. Article

    Open Access

    Develo** VISO: Vaccine Information Statement Ontology for patient education

    To construct a comprehensive vaccine information ontology that can support personal health information applications using patient-consumer lexicon, and lead to outcomes that can improve patient education.

    Muhammad Amith, Yang Gong, Rachel Cunningham, Julie Boom in Journal of Biomedical Semantics (2015)

  12. Article

    Open Access

    A use case study on late stent thrombosis for ontology-based temporal reasoning and analysis

    In this paper, we show how we have applied the Clinical Narrative Temporal Relation Ontology (CNTRO) and its associated temporal reasoning system (the CNTRO Timeline Library) to trend temporal information with...

    Kim Clark, Deepak Sharma, Rui Qin, Christopher G Chute in Journal of Biomedical Semantics (2014)

  13. Article

    Open Access

    Network-based analysis reveals distinct association patterns in a semantic MEDLINE-based drug-disease-gene network

    A huge amount of associations among different biological entities (e.g., disease, drug, and gene) are scattered in millions of biomedical articles. Systematic analysis of such heterogeneous data can infer nove...

    Yuji Zhang, Cui Tao, Guoqian Jiang, Asha A Nair, Jian Su in Journal of Biomedical Semantics (2014)

  14. Article

    Open Access

    OAE: The Ontology of Adverse Events

    A medical intervention is a medical procedure or application intended to relieve or prevent illness or injury. Examples of medical interventions include vaccination and drug administration. After a medical int...

    Yongqun He, Sirarat Sarntivijai, Yu Lin, Zuoshuang **ang in Journal of Biomedical Semantics (2014)

  15. Article

    Open Access

    A 2013 workshop: vaccine and drug ontology studies (VDOS 2013)

    The 2013 “Vaccine and Drug Ontology Studies” (VDOS 2013) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have contributed to dramatic i...

    Cui Tao, Yongqun He, Sivaram Arabandi in Journal of Biomedical Semantics (2014)

  16. Article

    Open Access

    Network-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology

    Ontologies are useful in many branches of biomedical research. For instance, in the vaccine domain, the community-based Vaccine Ontology (VO) has been widely used to promote vaccine data standardization, integ...

    Yuji Zhang, Cui Tao, Yongqun He, Pradip Kanjamala in Journal of Biomedical Semantics (2013)

  17. Article

    Open Access

    Ontology-based time information representation of vaccine adverse events in VAERS for temporal analysis

    The U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) provides a valuable data source for post-vaccination adverse event analyses. The structured data in the system has been widely used, but the info...

    Cui Tao, Yongqun He, Hannah Yang, Gregory A Poland in Journal of Biomedical Semantics (2012)

  18. Article

    Open Access

    A 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012)

    Vaccines and drugs have contributed to dramatic improvements in public health worldwide. Over the last decade, there have been efforts in develo** biomedical ontologies that represent various areas associate...

    Yongqun He, Luca Toldo, Gully Burns, Cui Tao in Journal of Biomedical Semantics (2012)