2,843 Result(s)
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**u Li Chen
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Article
Open AccessMiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification
Female infertility due to declining oocyte quality with age remains a significant challenge for patients and physicians, despite extensive research efforts. Recent studies suggest that microRNAs (miRNAs), whic...
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Thermal fatigue cracks in WC-10Ni + AgCuTi composite coatings
In this study, a WC-10Ni + AgCuTi/Cu composite coating was applied to a copper substrate using vacuum brazing. The initiation and propagation of thermal fatigue cracks in the composite coating were investigate...
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Effects of DeSUMOylated Spastin on AMPA Receptor Surface Delivery and Synaptic Function Are Enhanced by Phosphorylating at Ser210
Surface trafficking of AMPA receptors (AMPARs) is one of the important mechanisms mediating synaptic plasticity which is essential for cognitive functions such as learning and memory. Spastin, as a novel bindi...
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SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood–Brain Barrier Impairment After Cerebral Venous Thrombosis
Cerebral venous thrombosis (CVT) is a neurovascular disease with recently increasing incidence. Aseptic inflammatory responses play an important role in the pathology of CVT. Recent studies report that neutrop...
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Open AccessRelationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction
The epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction (HFmrEF) patients and its impact on outcomes remains unclear. We attempt to ...
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A review on the enantioselective distribution and toxicity of chiral pesticides in aquatic environment
Chiral pesticides account for about 40% of the total pesticides. In the process of using pesticides, it will inevitably flow into the surface water and even penetrate into the groundwater through surface runof...
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Open AccessSynergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether pyroptosis can be a death form of MC remains unknown. Proteasom...
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Open AccessCorrection: Qualitative and quantitative assessment of non-clear cell renal cell carcinoma using contrast-enhanced ultrasound
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Two-phase cost-sensitive-learning-based framework on customer-side quality inspection for TFT-LCD industry
The Covid-19 outbreak in 2020 boosted the stay-at-home economy, causing a surge in electronics industry demand, especially benefiting the LCD panel sector. However, as the pandemic situation improved, countrie...
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Open AccessRisk of stress cardiomyopathy associated with selective serotonin reuptake inhibitors and serotonin and norepinephrine reuptake inhibitors: a real-world pharmacovigilance analysis
Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are reported to cause stress cardiomyopathy (SC). This study evaluated the association between SSRI/...
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Comment on “Effect of finerenone on cardiovascular events in kidney disease and/or diabetes”
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Phase Equilibria of Quaternary System KCl + BaCl2 + SrCl2 + H2O and Its Ternary Systems at 323 K
To fully understand the metallogenic regularity and the geochemical equilibrium rules of brine migration and transformation among potassium, barium and strontium in gas field water, the isothermal dissolution ...
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Open AccessHalofuginone Inhibits Osteoclastogenesis and Enhances Osteoblastogenesis by Regulating Th17/Treg Cell Balance in Multiple Myeloma Mice with Bone Lesions
Evidences shows that T helper 17 (Th17) and regulatory T (Treg) cells imbalance plays a critical role in bone lesions of MM patients. Therefore, regulating the Th17/Treg imbalance may be beneficial for bone le...
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Open AccessSTAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells
The apoptosis-resistant pulmonary arterial endothelial cells (PAECs) are known to be major players in the pulmonary remodeling of pulmonary arterial hypertension (PAH) and exhibit an abnormal metabolic profile...
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Clinical impact and role of major vessels involvement in laparoscopic resection for hepatic hemangioma
Severe bleeding remains a significant concern in laparoscopic resection for hepatic hemangioma. It is rarely reported that how the degree of major vessels involvement impacts on severe bleeding. The present st...
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Open AccessThe predictive value of GLIM criteria on clinical outcomes and responses to nutritional support in patients with neurocritical illnesses
Neurocritically ill patients frequently exhibit coma, gastroparesis, and intense catabolism, leading to an increased risk of malnutrition. The Global Leadership Initiative on Malnutrition (GLIM) criteria for t...
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Comparison of carbon coating and MCMB structures used in graphite anodes for potassium ion batteries
This study comprehensively investigates three types of graphite materials as potential anodes for potassium-ion batteries. Natural graphite, artificial carbon-coated graphite, and mesocarbon microbeads (MCMB) ...
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Open AccessImpaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt ...
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A class of fully nonlinear equations on Riemannian manifolds with negative curvature
In this paper, we consider a class of fully nonlinear equations on Riemannian manifolds with negative curvature which naturally arise in conformal geometry. Moreover, we prove the a priori estimates for soluti...
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Open AccessActivation of lncRNA DANCR by H3K27 acetylation regulates proliferation of colorectal cancer cells
The long noncoding DANCR functions as a tumor oncogene in many cancers, including colorectal cancer (CRC). However, the molecular mechanism of DANCR in CRC has not been explored. This study probed the function...
