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  1. Article

    Open Access

    Response to chemotherapy could predict the prognosis of esophageal squamous cell carcinoma treated with neoadjuvant docetaxel, cisplatin, and fluorouracil (DCF) followed by surgery: long-term results in a single institute

    Preoperative chemotherapy with 5-fluorouracil and cisplatin (FP) followed by surgery has been considered a standard treatment for patients with stage II/III esophageal squamous cell carcinoma (ESCC) based on t...

    Yasuyoshi Sato, Kazuhiko Mori, Shinichiro Atsumi, Kei Sakamoto, Shuichiro Oya in Esophagus (2024)

  2. No Access

    Article

    Incidence of four major osteoporotic fragility fractures among older individuals in Sado, Japan, in 2020

    This study compared the 2020 incidence of fragility fractures in Sado City with those from 2004 to 2015.

    Norio Imai, Asami Nozaki, Yugo Shobugawa in Journal of Bone and Mineral Metabolism (2024)

  3. Article

    Open Access

    Transparency-enhancing technology allows the three-dimensional assessment of esophageal carcinoma obtained by endoscopic submucosal dissection

    Although much progress has been made in diagnosis of carcinomas, no established methods have been confirmed to elucidate their morphological features.

    Yuichi Asahina, Munetoshi Hinata, Asami Tanaka, Kaori Oshio, Haruki Ogawa in Esophagus (2024)

  4. Article

    Open Access

    Hydrogen bond symmetrisation in D2O ice observed by neutron diffraction

    Hydrogen bond symmetrisation is the phenomenon where a hydrogen atom is located at the centre of a hydrogen bond. Theoretical studies predict that hydrogen bonds in ice VII eventually undergo symmetrisation up...

    Kazuki Komatsu, Takanori Hattori, Stefan Klotz, Shinichi Machida in Nature Communications (2024)

  5. Article

    Open Access

    Veno-venous extracorporeal membrane oxygenation in managing acute respiratory distress syndrome associated with hemolytic uremic syndrome and septic shock: a case report

    Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a rescue therapy for severe respiratory failure in which conventional mechanical ventilation therapy is unsuccessful. Hemolysis during VV-ECMO suppo...

    Genta Kinoshita, Asami Ito-Masui, Takafumi Kato in Journal of Artificial Organs (2024)

  6. Article

    Open Access

    Sedentary behaviour may cause differences in physical outcomes and activities of daily living in older cardiovascular disease patients participating in phase I cardiac rehabilitation

    This study aimed to investigate the rate of sedentary behaviour and differences in physical outcomes and activities of daily living (ADL) based on sedentary behaviour time of hospitalized older cardiovascular ...

    Kazuhiro P. Izawa, Kodai Ishihara, Yuji Kanejima, Masahiro Kitamura in Scientific Reports (2024)

  7. Article

    Open Access

    Effects of brief family psychoeducation on family caregiver burden of people with schizophrenia provided by psychiatric visiting nurses: a cluster randomised controlled trial

    The purpose of this study was to examine the effects of a brief family psychoeducation (BFP) programme provided by psychiatric visiting nurses on caregiver burden of family caregivers of people with schizophre...

    Naonori Yasuma, Sayaka Sato, Sosei Yamaguchi, Asami Matsunaga in BMC Psychiatry (2024)

  8. Article

    Open Access

    A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism

    Memory T cells demonstrate superior in vivo persistence and antitumor efficacy. However, methods for manufacturing less differentiated T cells are not yet well-established. Here, we show that producing chimeri...

    Shin-ichiro Takayanagi, Sayaka Chuganji, Masahiro Tanaka, Bo Wang in Communications Biology (2024)

  9. Article

    Open Access

    Retraction Note: Investigation of molecular biomarker candidates for diagnosis and prognosis of chronic periodontitis by bioinformatics analysis of pooled microarray gene expression datasets in Gene Expression Omnibus (GEO)

    Asami Suzuki, Tetsuro Horie, Yukihiro Numabe in BMC Oral Health (2024)

  10. Article

    Open Access

    Relationship among muscle strength, muscle endurance, and skeletal muscle oxygenation dynamics during ramp incremental cycle exercise

    Peak oxygen uptake (VO2), evaluated as exercise tolerance, is a strong predictor of life prognosis regardless of health condition. Several previous studies have reported that peak VO2 is higher in those with a gr...

    Shinji Nemoto, Tohru Nakabo, Naonori Tashiro, Asami Kishino in Scientific Reports (2024)

  11. No Access

    Article

    Liver Resection Under Total Hepatic Vascular Exclusion with In Situ Hypothermic Isolated Hepatic Perfusion for Advanced Liver Tumors

    Continuous dissection or simultaneous reconstruction of the hepatic vein (HV) and inferior vena cava (IVC) was achieved under total hepatic vascular exclusion (THVE) with in situ hypothermic isolated hepatic p...

    Hiroshi Sadamori MD, PhD, Kazuteru Monden MD, PhD in Annals of Surgical Oncology (2024)

  12. Article

    Open Access

    Exploring fluoropolymers for fabrication of femtoliter chamber arrays used in digital bioanalysis

    The global supply of fluoropolymers and fluorinated solvents is decreasing due to environmental concerns regarding polyfluoroalkyl substances. CYTOP has been used for decades primarily as a component of a femt...

    Jun Ando, Kazue Murai, Makiko Mori, Tomoe Michiyuki, Tatsuya Iida in Scientific Reports (2024)

  13. Article

    Open Access

    Clinical features of patients with systemic sclerosis positive for anti-SS-A antibody: a cohort study of 156 patients

    Anti-SS-A/Ro antibody (anti-SSA), the diagnostic marker of Sjögren’s syndrome (SS), is often detected in systemic sclerosis (SSc). Some patients are diagnosed with SSc/SS overlap syndromes, while there are ant...

    Tomoya Watanabe, Yasushi Ototake, Asami Akita, Mao Suzuki in Arthritis Research & Therapy (2024)

  14. Article

    Open Access

    Evaluation of the exit screening policy among travelers arriving from Asian and pacific nations

    The Japanese government has instituted border control measures against COVID-19, including entry and exit screening of people arriving from overseas. We sought to evaluate the effectiveness of the exit screeni...

    Shiqi Liu, Asami Anzai, Hiroshi Nishiura in BMC Infectious Diseases (2024)

  15. No Access

    Article

    Thyrolinguofacial trunk arising from the common carotid artery and diagnosed by computed tomography angiography

    Various variations in the head and neck vasculature have been reported. The purpose of this report is to describe an extremely rare case of thyrolinguofacial trunk (TLFT) arising from the common carotid artery...

    Shiho Asami, Akira Uchino, Yuki Natsuyama, Yoko Usami in Surgical and Radiologic Anatomy (2024)

  16. No Access

    Article

    Correlation between the spread of IMP-producing bacteria and the promoter strength of blaIMP genes

    The first report of transmissible carbapenem resistance encoded by blaIMP-1 was discovered in Pseudomonas aeruginosa GN17203 in 1988, and blaIMP-1 has since been detected in other bacteria, including Enterobacter...

    Yuta Kikuchi, Mariko Yoshida, Asaomi Kuwae, Yukihiro Asami in The Journal of Antibiotics (2024)

  17. No Access

    Article

    An approach for improvement of the accuracy of cancer gene panel testing

    Tissue-based comprehensive genomic profiling (CGP) is increasingly being employed for genotype-directed therapies in patients with advanced cancer. However, tissue availability may limit their potential applic...

    Kiyomi Imoto, Hiroyuki Yamamoto, Chie Ohkawa in International Journal of Clinical Oncology (2024)

  18. No Access

    Article

    Efflux pump inhibitor, phenylalanine-arginine beta-naphthylamide analog potentiates the activity of 5-O-mycaminosyltylonolide for multi-drug resistant Pseudomonas aeruginosa

    The emergence and spread of antimicrobial resistance are global threats. Pseudomonas aeruginosa (P. aeruginosa) is responsible for a substantial proportion of this global health issue because of its intrinsic res...

    Aoi Kimishima, Masako Honsho, Junsei Terai, Paul Wasuwanich in The Journal of Antibiotics (2024)

  19. No Access

    Article

    Preoperative NUn score serves as a robust predictor of overall and disease-specific survivals following radical surgery for gastric cancer

    Methods to preoperatively stratify oncological risks associated with gastric cancer (GC) are limited. Host inflammatory parameters, i.e., serum C-reactive protein (CRP) and albumin levels, are known to be asso...

    Masayuki Urabe, Yasuhiro Okumura, Asami Okamoto in Langenbeck's Archives of Surgery (2024)

  20. No Access

    Article

    Immune checkpoint inhibitor-associated colitis in unresectable hepatocellular carcinoma: two cases of early onset after treatment with durvalumab plus tremelimumab

    The HIMALAYA trial is the first chemotherapeutic trial to demonstrate the efficacy of combined immune checkpoint inhibitors (ICIs) for unresectable hepatocellular carcinoma (u-HCC). The STRIDE regimen used in ...

    Hiroaki Abe, Kei Endo, Hidekatsu Kuroda in Clinical Journal of Gastroenterology (2024)

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