12,603 Result(s)
-
Article
Improvement of the Unequal Division Shear Zone Model Based on Sensitivity Analysis and Classification of Uncertain Parameters
Inversion of relevant parameters of cutting analysis model through experimental data is an effective method to improve the prediction accuracy of the model. In view of the present situation that the prediction...
-
Article
Open AccessBroadening bandgaps in a multi-resonant piezoelectric metamaterial plate via bandgap merging phenomena
Locally resonant metamaterials usually have narrow bandgaps, which significantly limits their applications in realistic engineering environments. In this paper, an optimization method based on the genetic algo...
-
Article
Open AccessMultiplex LAMP assay for detecting the prevalent species of dust mites Dermatophagoides farinae and Dermatophagoides pteronyssinus in the domestic environment
Dermatophagoides farina (D. farinae) and Dermatophagoides pteronyssinus (D. pteronyssinus) are the prevalent kinds of house dust mites (HDMs). HDMs are common inhalant allergens that cause a range of allergic dis...
-
Article
Open AccessCholine consumption reduces CVD risk via body composition modification
Despite extensive research on the relationship between choline and cardiovascular disease (CVD), conflicting findings have been reported. We aim to investigate the relationship between choline and CVD. Our ana...
-
Article
Open AccessPlasmonic trimers designed as SERS-active chemical traps for subty** of lung tumors
Plasmonic materials can generate strong electromagnetic fields to boost the Raman scattering of surrounding molecules, known as surface-enhanced Raman scattering. However, these electromagnetic fields are hete...
-
Article
Open AccessTherapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis
Mucus injury associated with goblet cell (GC) depletion constitutes an early event in inflammatory bowel disease (IBD). Using single-cell sequencing to detect critical events in mucus dysfunction, we discover ...
-
Article
Open AccessIntraspecific diploidization of a halophyte root fungus drives heterosis
How organisms respond to environmental stress is a key topic in evolutionary biology. This study focused on the genomic evolution of Laburnicola rhizohalophila, a dark-septate endophytic fungus from roots of a ha...
-
Article
Open AccessInhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer
Tumor cells reprogram their metabolism to produce specialized metabolites that both fuel their own growth and license tumor immune evasion. However, the relationships between these functions remain poorly unde...
-
Article
Open AccessA near complete genome assembly of the East Friesian sheep genome
Advancements in sequencing have enabled the assembly of numerous sheep genomes, significantly advancing our understanding of the link between genetic variation and phenotypic traits. However, the genome of Eas...
-
Article
Open AccessOrganocatalytic asymmetric synthesis of Si-stereogenic silacycles
A strong and confined Brønsted acid catalyzed enantioselective cyclization of bis(methallyl)silanes provides enantioenriched Si-stereogenic silacycles. High enantioselectivities of up to 96.5:3.5 er were obtained...
-
Article
Open AccessMap** of 10-km daily diffuse solar radiation across China from reanalysis data and a Machine-Learning method
Diffuse solar radiation (DSR) plays a critical role in renewable energy utilization and efficient agricultural production. However, there is a scarcity of high-precision, long-term, and spatially continuous da...
-
Article
Open AccessFew-shot RUL prediction for engines based on CNN-GRU model
In the realm of prognosticating the remaining useful life (RUL) of pivotal components, such as aircraft engines, a prevalent challenge persists where the available historical life data often proves insufficien...
-
Article
Open AccessCompartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes
A stable mitochondrial pool is crucial for healthy cell function and survival. Altered redox biology can adversely affect mitochondria through induction of a variety of cell death and survival pathways, yet th...
-
Article
Open AccessHabitat radiomics and deep learning fusion nomogram to predict EGFR mutation status in stage I non-small cell lung cancer: a multicenter study
Develop a radiomics nomogram that integrates deep learning, radiomics, and clinical variables to predict epidermal growth factor receptor (EGFR) mutation status in patients with stage I non-small cell lung can...
-
Article
Open AccessRibonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
Antimicrobial proteins contribute to host-microbiota interactions and are associated with inflammatory bowel disease (IBD), but our understanding on antimicrobial protein diversity and functions remains incomp...
-
Article
Open AccessUnlocking the function promiscuity of old yellow enzyme to catalyze asymmetric Morita-Baylis-Hillman reaction
Exploring the promiscuity of native enzymes presents a promising strategy for expanding their synthetic applications, particularly for catalyzing challenging reactions in non-native contexts. In this study, we...
-
Article
Open AccessFormation of the junctions between lymph follicles in the Peyer's patches even before postweaning activation
Peyer’s patches (PPs), which contain an abundance of B and T cells, play a key role in inducing pivotal immune responses in the intestinal tract. PPs are defined as aggregated lymph follicles, which consist of...
-
Article
Open AccessUnveiling the nonlinear dynamics of player performance in China’s super league as a function of age
To explore the dynamics in physical and technical performance of professional football players and changes across age groups. Match statistics were collected from 1900 games across ten seasons (2012–2021) in t...
-
Article
Open AccessAssociation of the hemoglobin, albumin, lymphocyte, and platelet score with the risk of Erectile dysfunction: a cross-sectional study
Erectile dysfunction (ED) is related to nutritional and inflammatory factors. The hemoglobin, albumin, lymphocyte, and platelet score (HALP), a new index reflecting the nutritional and inflammatory status, has...
-
Article
Open AccessEmbedding textile capacitive sensing into smart wearables as a versatile solution for human motion capturing
This work presents a novel and versatile approach to employ textile capacitive sensing as an effective solution for capturing human body movement through fashionable and everyday-life garments. Conductive text...