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    Article

    Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy

    Some studies have shown that gut microbiota along with its metabolites is closely associated with diabetic mellitus (DM). In this study we explored the relationship between gut microbiota and kidney injuries o...

    Chen-chen Lu, Ze-bo Hu, Ru Wang, Ze-hui Hong, Jian Lu in Acta Pharmacologica Sinica (2020)

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    Platelet microparticles contribute to aortic vascular endothelial injury in diabetes via the mTORC1 pathway

    Platelet microparticles (PMPs) are closely associated with diabetic macrovascular complications. The present study aimed to investigate the effects of PMPs in diabetes on aortic vascular endothelial injury and...

    Gui-hua Wang, Kun-ling Ma, Yang Zhang, Ze-bo Hu, Liang Liu in Acta Pharmacologica Sinica (2019)

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    Chapter

    Lipid Metabolism Disorder and Renal Fibrosis

    Since the lipid nephrotoxicity hypothesis was proposed in 1982, increasing evidence has supported the hypothesis that lipid abnormalities contributed to the progression of glomerulosclerosis. In this chapter, ...

    **ao-Gang Du, **ong-Zhong Ruan in Renal Fibrosis: Mechanisms and Therapies (2019)

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    Article

    Influence of HBV gene heterogeneity on the failure of immunization with HBV vaccines in eastern China

    The influence of hepatitis B virus (HBV) gene heterogeneity on the failure of HBV vaccination in eastern China remains unknown. Here, we assigned 78 hepatitis B surface antigen (HBsAg)-carrier mothers to two g...

    She-Lan Liu, Ying Dong, Li Zhang, Min-Wei Li, Jian-er Wo, Li-Wei Lu in Archives of Virology (2009)