410 Result(s)
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Open AccessPlasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease
Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared...
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Open AccessGeneral negative pressure annealing approach for creating ultra-high-loading single atom catalyst libraries
Catalyst systems populated by high-density single atoms are crucial for improving catalytic activity and selectivity, which can potentially maximize the industrial prospects of heterogeneous single-atom cataly...
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Open AccessA tabular data generation framework guided by downstream tasks optimization
Recently, generative models have been gradually emerging into the extended dataset field, showcasing their advantages. However, when it comes to generating tabular data, these models often fail to satisfy the ...
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Open AccessChiral multiferroicity in two-dimensional hybrid organic-inorganic perovskites
Chiral multiferroics offer remarkable capabilities for controlling quantum devices at multiple levels. However, these materials are rare due to the competing requirements of long-range orders and strict symmet...
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Open AccessChromosome-level genome assembly of Cnidium monnieri, a highly demanded traditional Chinese medicine
Cnidium monnieri, a medicinal herb of the Cnidium genus and the Apiaceae family, is among the most important traditional Chinese medicines and is widely distributed in China. However, to date, no C. monnieri-rela...
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Open AccessRBC transfusion and necrotizing enterocolitis in very preterm infants: a multicenter observational study
The causal relationship between Packed red blood cell (RBC) transfusion and necrotizing enterocolitis (NEC) remains uncertain. This study aims to provide an exploration of transfusion and NEC in very preterm i...
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Open AccessATP biosensor reveals microbial energetic dynamics and facilitates bioproduction
Adenosine-5’-triphosphate (ATP), the primary energy currency in cellular processes, drives metabolic activities and biosynthesis. Despite its importance, understanding intracellular ATP dynamics’ impact on bio...
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Open AccessComparison of tacrolimus with or without prednisone therapy in primary membranous nephropathy: a retrospective clinical study
Previous studies showed tacrolimus monotherapy and dual therapy with tacrolimus and prednisone as effective treatment modalities in managing membranous nephropathy. However, few studies have compared these the...
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Open AccessPhotoelectrochemical Fe/Ni cocatalyzed C−C functionalization of alcohols
The simultaneous activation of reactants on the anode and cathode via paired electrocatalysis has not been extensively demonstrated. This report presents a paired oxidative and reductive catalysis based on ear...
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Open AccessCassini spacecraft reveals global energy imbalance of saturn
The global energy budget is pivotal to understanding planetary evolution and climate behaviors. Assessing the energy budget of giant planets, particularly those with large seasonal cycles, however, remains a c...
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Open AccessElectrochemical synthesis of peptide aldehydes via C‒N bond cleavage of cyclic amines
Peptide aldehydes are crucial biomolecules essential to various biological systems, driving a continuous demand for efficient synthesis methods. Herein, we develop a metal-free, facile, and biocompatible strat...
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Open AccessHigh performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants
Cytosine base editors (CBEs) and adenine base editors (ABEs) enable precise C-to-T and A-to-G edits. Recently, ABE8e, derived from TadA-8e, enhances A-to-G edits in mammalian cells and plants. Interestingly, T...
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Open AccessProgrammable melanoma-targeted radio-immunotherapy via fusogenic liposomes functionalized with multivariate-gated aptamer assemblies
Radio-immunotherapy exploits the immunostimulatory features of ionizing radiation (IR) to enhance antitumor effects and offers emerging opportunities for treating invasive tumor indications such as melanoma. H...
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Open AccessDispersive Fourier transform based dual-comb ranging
Laser-based light detection and ranging (LIDAR) offers a powerful tool to real-timely map spatial information with exceptional accuracy and owns various applications ranging from industrial manufacturing, and ...
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Open AccessSOD3 suppresses early cellular immune responses to parasite infection
Host immune responses are tightly controlled by various immune factors during infection, and protozoan parasites also manipulate the immune system to evade surveillance, leading to an evolutionary arms race in...
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Open AccessAssociations between metabolic dysfunction-associated fatty liver disease, chronic kidney disease, and abdominal obesity: a national retrospective cohort study
Metabolic dysfunction-associated fatty liver disease (MAFLD) and chronic kidney disease (CKD) present notable health challenges, however, abdominal obesity has received scant attention despite its potential ro...
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Open AccessStudy on static and dynamic mechanical properties and microstructure of silica fume-polypropylene fiber modified rubber concrete
Through tests and micro-observations, the static and dynamic mechanical properties and microstructure of rubber concrete samples modified with varying amounts of silica fume and polypropylene fiber content wer...
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Open AccessMulti-resource dynamic coordinated planning of flexible distribution network
The flexible distribution network presents a promising architecture to accommodate highly integrated distributed generators and increasing loads in an efficient and cost-effective way. The distribution network...
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Open AccessDCTPep, the data of cancer therapy peptides
With the discovery of the therapeutic activity of peptides, they have emerged as a promising class of anti-cancer agents due to their specific targeting, low toxicity, and potential for high selectivity. In pa...
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Open AccessConstruction and optimization of Green Infrastructure Network in mountainous cities: a case study of Fuzhou, China
Green infrastructure networks enhance the protection and improvement of urban ecological environments, augment the efficiency and quality of ecosystem services, and furnish residents with healthier and more co...
