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2,592 Result(s)
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Article
Open AccessPRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression
SNCAIP duplication may promote Group 4 medulloblastoma via induction of PRDM6, a poorly characterized member of the PRDF1 and RIZ1 homology domain-containing (PRDM) family of transcription factors. Here, we inves...
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Open AccessThe type III effector NopL interacts with GmREM1a and GmNFR5 to promote symbiosis in soybean
The establishment of symbiotic interactions between leguminous plants and rhizobia requires complex cellular programming activated by Rhizobium Nod factors (NFs) as well as type III effector (T3E)-mediated sym...
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Plasticity in single-crystalline Mg3Bi2 thermoelectric material
Most of the state-of-the-art thermoelectric materials are inorganic semiconductors. Owing to the directional covalent bonding, they usually show limited plasticity at room temperature1,2, for example, with a tens...
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Open AccessStrong angular and spectral narrowing of electroluminescence in an integrated Tamm-plasmon-driven halide perovskite LED
Next-generation light-emitting applications such as displays and optical communications require judicious control over emitted light, including intensity and angular dispersion. To date, this remains a challen...
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Open AccessGerm granule compartments coordinate specialized small RNA production
Germ granules are biomolecular condensates present in most animal germ cells. One function of germ granules is to help maintain germ cell totipotency by organizing mRNA regulatory machinery, including small RN...
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Open AccessMechanisms underlying the therapeutic effects of Gang Huo Qing wen granules in the treatment of influenza based on network pharmacology, molecular docking and molecular dynamics
Influenza (Flu) is a severe health, medical, and economic problem, but no medication that has excellent outcomes and lowers the occurrence of these problems is now available. GanghuoQingwenGranules (GHQWG) is a c...
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Open AccessNumerical simulation on transient electromagnetic response of separation layer water in coal seam roof
Mining stress induces deformation and fracture of the overlaying rock, which will result in water filling the separation layer if the aquifer finds access to abscission space along the fracture channels. Accur...
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Open AccessComprehensive analysis of disulfidptosis-related genes reveals the effect of disulfidptosis in ulcerative colitis
Ulcerative colitis (UC) is a chronic inflammatory condition of the intestinal tract. Various programmed cell death pathways in the intestinal mucosa are crucial to the pathogenesis of UC. Disulfidptosis, a rec...
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Open AccessStable and efficient CsPbI3 quantum-dot light-emitting diodes with strong quantum confinement
Even though lead halide perovskite has been demonstrated as a promising optoelectronic material for next-generation display applications, achieving high-efficiency and stable pure-red (620~635 nm) emission to ...
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Open AccessLILRB4 knockdown inhibits aortic dissection development by regulating pyroptosis and the JAK2/STAT3 signaling pathway
Aortic dissection (AD) is a life-threatening condition with a high mortality rate and without effective pharmacological therapies. Our previous study illustrated that leukocyte immunoglobulin-like receptor B4 ...
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Open AccessImage processing based modeling for Rosa roxburghii fruits mass and volume estimation
The mass and volume of Rosa roxburghii fruits are essential for fruit grading and consumer selection. Physical characteristics such as dimension, projected area, mass, and volume are interrelated. Image-based mas...
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Open AccessSurface photogalvanic effect in Ag2Te
The bulk photovoltaic effect (BPVE) in non-centrosymmetric materials has attracted significant attention in recent years due to its potential to surpass the Shockley-Queisser limit. Although these materials ar...
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Open AccessReappropriating the communal past: lineage tradition revival as a way of constructing collective identity in Huizhou, China
This article discusses the reappropriation and redefinition of heritage and tradition as a process of purposeful and selective value extraction by various groups at the local level in Huizhou, China, based on ...
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Open AccessBarbed arrow-like structure membrane with ultra-high rectification coefficient enables ultra-fast, highly-sensitive lateral-flow assay of cTnI
Acute myocardial infarction (AMI) has become a public health disease threatening public life safety due to its high mortality. The lateral-flow assay (LFA) of a typical cardiac biomarker, troponin I (cTnI), is...
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Open AccessAnalysis of the multiple drivers of vegetation cover evolution in the Taihangshan-Yanshan region
The Taihangshan-Yanshan region (TYR) is an important ecological barrier area for Bei**g-Tian**-Hebei, and the effectiveness of its ecological restoration and protection is of great significance to the ecolog...
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Open AccessA non-invasive diagnostic nomogram for CHB-related early cirrhosis: a prospective study
This study aimed to construct a non-invasive diagnostic nomogram based on high-frequency ultrasound and magnetic resonance imaging results for early liver cirrhosis patients with chronic hepatitis B (CHB) whic...
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Open AccessA single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma
Teratoma, due to its remarkable ability to differentiate into multiple cell lineages, is a valuable model for studying human embryonic development. The similarity of the gene expression and chromatin accessibi...
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Open AccessChromosome-level genome assembly of Helwingia omeiensis: the first genome in the family Helwingiaceae
Helwingia, a shrub of the monotypic cosmopolitan family Helwingiaceae, is distinguished by its inflorescence, in which flowers are borne on the midrib of the leaf—a trait not commonly observed in related plant fa...
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Open AccessStructure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2
Proline is widely known as the only proteogenic amino acid with a secondary amine. In addition to its crucial role in protein structure, the secondary amino acid modulates neurotransmission and regulates the k...
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Open AccessBidirectional causality between idiopathic sudden sensorineural hearing loss and depression: a Mendelian randomization study
Idiopathic Sudden Sensorineural Hearing Loss (ISSHL) is a sudden onset, unexplained sensorineural hearing loss. Depression is a common mental disorder and a leading cause of disability. Here, We used a two-sam...