3 Result(s)

Article

Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling

Glomerular endothelial cells (GEnCs) dysfunction occurs at the early stage of diabetic nephropathy (DN). One of its characteristics is endothelial-to-mesenchymal transition (EndMT). Heparanase (HPSE) is the on...

Kaili Chang, Qiyuan **e, Jianying Niu, Yong Gu, Zhonghua Zhao… in Cell Death Discovery (2022)

Article

Correction: Heparanase promotes endothelial-to-mesenchymal transition in diabetic glomerular endothelial cells through mediating ERK signaling

Kaili Chang, Qiyuan **e, Jianying Niu, Yong Gu, Zhonghua Zhao… in Cell Death Discovery (2022)

Article

Preclinical evaluation of the SARS-CoV-2 M^pro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir

Although vaccines are available for SARS-CoV-2, antiviral drugs such as nirmatrelvir are still needed, particularly for individuals in whom vaccines are less effective, such as the immunocompromised, to preven...

**aoxin Chen, **aodong Huang, Qinhai Ma, Petr Kuzmič, Biao Zhou… in Nature Microbiology (2024)