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  1. No Access

    Article

    Cerebral Hemodynamics Underlying Artery-to-Artery Embolism in Symptomatic Intracranial Atherosclerotic Disease

    Artery-to-artery embolism (AAE) is a common stroke mechanism in intracranial atherosclerotic disease (ICAD), associated with a considerable risk of recurrent stroke. We aimed to investigate cerebral hemodynami...

    Xueyan Feng, Hui Fang, Bonaventure Y. M. Ip, Ka Lung Chan in Translational Stroke Research (2024)

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    Article

    Cobalt-decorated carbon nanotube bottlebrushes for boosting polysulfide conversion in lithium-sulfur batteries

    Develo** superhierarchical carbon materials with multiple levels of structural hierarchy including porous structure, hybrid skeleton and/or topological morphology, is highly desirable to fulfill the demands ...

    Junlong Huang 黄俊龙, Kunyi Leng 冷坤怡, Zongheng Cen 岑宗恒 in Science China Materials (2023)

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    Article

    Collateral Flow in Intracranial Atherosclerotic Disease

    Intracranial atherosclerotic disease (ICAD) is a major cause of ischemic stroke and transient ischemic attack (TIA) worldwide. The culprit of ICAD is frequently a high-grade intracranial atherosclerotic stenos...

    **nyi Leng, Thomas W. Leung in Translational Stroke Research (2023)

  4. Article

    Open Access

    Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis

    Drug–drug interactions between direct oral anticoagulants (DOAC) and antiseizure medications via the cytochrome P450 (CYP) or the P-glycoprotein (P-gp) systems may lead to under-anticoagulation. The clinical r...

    Bonaventure Y. Ip, Ho Ko, Grace LH Wong, Terry CF Yip, Louis HS Lau in CNS Drugs (2022)

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    Article

    Small vessel disease burden may not portend unfavorable outcome after thrombectomy for acute large vessel occlusion

    We aimed to investigate the correlation between an overall cerebral small vessel disease (CSVD) burden and outcomes after endovascular treatment (EVT) for patients with acute ischemic stroke (AIS) due to large...

    Lina Zheng, **nyi Leng, **ming Nie, Hongyi Yan, Xuan Tian in European Radiology (2022)

  6. Article

    Open Access

    Screening for chronic conditions with reproductive factors using a machine learning based approach

    A large proportion of cases with chronic conditions including diabetes or pre-diabetes, hypertension and dyslipidemia remain undiagnosed. To include reproductive factors (RF) might be able to improve current s...

    Siyu Tian, Weinan Dong, Ka Lung Chan, **nyi Leng in Scientific Reports (2020)

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    Reference Work Entry In depth

    Intracranial Atherosclerosis

    Atherosclerotic and arteriolosclerotic diseases of the cervicocerebral arteries are prevalent across the world, respectively, affecting arteries from large to small and distal arterioles. This chapter is focus...

    **nyi Leng, David S. Liebeskind in Neurovascular Imaging (2016)

  8. Article

    Open Access

    Computational fluid dynamics of computed tomography angiography to detect the hemodynamic impact of intracranial atherosclerotic stenosis

    In symptomatic intracranial atherosclerotic stenosis (ICAS), its hemodynamic impact may affect the risk of stroke recurrence, in addition to the degree of luminal stenosis. We therefore conducted a pilot study...

    **nyi Leng, Fabien Scalzo, Albert K Fong, Mark Johnson in Neurovascular Imaging (2015)

  9. No Access

    Living Reference Work Entry In depth

    Intracranial Atherosclerosis

    Atherosclerotic and arteriolosclerotic diseases of the cervicocerebral arteries are prevalent across the world, respectively, affecting arteries from large to small and distal arterioles. This chapter is focus...

    **nyi Leng, David S. Liebeskind in Neurovascular Imaging