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Open AccessFuzzy evaluation and obstacle factors of urban ecological health changes in the Wei River Basin, northwest China
Urban ecological health is crucial for the long-term sustainable development of watershed. Accurately evaluating the health level of the ecological environment helps to develop reasonable strategies for ecolog...
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Article
Correction: Household Dependence on Forest Resources in the Luki Biosphere Reserve, Democratic Republic of CONGO
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Open AccessDeterministic positioning and alignment of a single-molecule exciton in plasmonic nanodimer for strong coupling
Experimental realization of strong coupling between a single exciton and plasmons remains challenging as it requires deterministic positioning of the single exciton and alignment of its dipole moment with the ...
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Article
Open AccessClinical Characteristics and Pathogen Spectrum of Male Genital Fungal Infections in Nanchang Area, South China
The cutaneous fungal infections in male genitalia are relatively rare, and often present with various atypical clinical symptoms. It was mainly reported in a small number of case reports, while data with large...
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Open AccessRemote effects of Tibetan Plateau spring land temperature on global subseasonal to seasonal precipitation prediction and comparison with effects of sea surface temperature: the GEWEX/LS4P Phase I experiment
The prediction skill for precipitation anomalies in late spring and summer months—a significant component of extreme climate events—has remained stubbornly low for years. This paper presents a new idea that ut...
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Open AccessHigh performance artificial visual perception and recognition with a plasmon-enhanced 2D material neural network
The development of neuromorphic visual systems has recently gained momentum due to their potential in areas such as autonomous vehicles and robotics. However, current machine visual systems based on silicon te...
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Open AccessMonomodular and multifunctional processive endocellulases: implications for swine nutrition and gut microbiome
Poor efficiency of dietary fibre utilization not only limits global pork production profit margin but also adversely affects utilization of various dietary nutrients. Poor efficiency of dietary nutrient utiliz...
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Open AccessMonolithic three-dimensional integration of RRAM-based hybrid memory architecture for one-shot learning
In this work, we report the monolithic three-dimensional integration (M3D) of hybrid memory architecture based on resistive random-access memory (RRAM), named M3D-LIME. The chip featured three key functional l...
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Open AccessATXN3 promotes prostate cancer progression by stabilizing YAP
Prostate cancer (PC) is the most common neoplasm and is the second leading cause of cancer-related deaths in men worldwide. The Hippo tumor suppressor pathway is highly conserved in mammals and plays an import...
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Open AccessRemimazolam Compared to Propofol During Hysteroscopy: A Safety and Efficacy Analysis
Propofol is the main drug used to induce sedation for endoscopic procedures, and few drugs had shaken its dominant clinical use for a decade until the development of remimazolam. Remimazolam has been demonstra...
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Open AccessRetraction Note: Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via PI3K/Akt signaling pathway
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Open AccessPeriosteum-inspired in situ CaP generated nanocomposite hydrogels with strong bone adhesion and superior stretchability for accelerated distraction osteogenesis
Distraction osteogenesis (DO) is an efficacious but lengthy procedure to reconstruct segmental bone defects under the principle of tension-stress, during which the periosteum-mediated mechanical stimulation pl...
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Open AccessArabidopsis γ-H2A.X-INTERACTING PROTEIN participates in DNA damage response and safeguards chromatin stability
Upon the occurrence of DNA double strand breaks (DSB), the proximal histone variant H2A.X is phosphorylated as γ-H2A.X, a critical signal for consequent DSB signaling and repair pathways. Although γ-H2A.X-trig...
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Open AccessMulti-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma
This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma (ESCC), which if diagnosed at advanced stages has <30% five-year survival r...
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Open AccessDissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis
Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the composition of ESCC tumors based on 208,65...
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Open AccessMicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling
Exosomes are extracellular vesicles of nano-structures and represent an emerging nano-scale acellular therapy in recent years. Tendon regeneration is a sophisticated process in the field of microsurgery due to...
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Open AccessPreclinical assessment on neuronal regeneration in the injury-related microenvironment of graphene-based scaffolds
As the application of graphene nanomaterials gets increasingly attractive in the field of tissue engineering and regenerative medicine, the long-term evaluation is necessary and urgent as to their biocompatibi...
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Open AccessExtracellular vesicles from hydroxycamptothecin primed umbilical cord stem cells enhance anti-adhesion potential for treatment of tendon injury
Peritendinous fibrosis represents a fibrotic healing process that usually occurs after tendon injury or surgery. This worldwide challenge hampers the functional rehabilitation and the mobility of extremities. ...
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Open AccessSingle-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
Esophageal squamous cell carcinoma (ESCC) is prevalent in some geographical regions of the world. ESCC development presents a multistep pathogenic process from inflammation to invasive cancer; however, what is...
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Open AccessFrequency Characteristics and Numerical Computation of Seismic Records Generated by a Giant Debris Flow in Zhouqu, Western China
The catastrophic Sanyanyu and Luojiayu debris flows, which were induced by heavy rain, struck Zhouqu County in Gannan Prefecture, Gansu Province, at approximately midnight, 7 August 2010 (Bei**g time, UTC + 8...