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  1. Article

    Open Access

    A machine-learning algorithm using claims data to identify patients with homozygous familial hypercholesterolemia

    Homozygous familial hypercholesterolemia (HoFH) is an underdiagnosed and undertreated ultra-rare disease. We utilized claims data from the Komodo Healthcare Map database to develop a machine-learning model to ...

    **g Gu, Matthew Epland, **nshuo Ma, **a Park, Robert J. Sanchez in Scientific Reports (2024)

  2. Article

    Open Access

    Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model

    Optogenetic manipulation and optical imaging in the near-infrared range allow non-invasive light-control and readout of cellular and organismal processes in deep tissues in vivo. Here, we exploit the advantage...

    Ludmila A. Kasatkina, Chenshuo Ma, Mikhail E. Matlashov, Tri Vu in Nature Communications (2022)

  3. Article

    Open Access

    Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe

    Mitochondria play a critical role in generating energy to support the entire lifecycle of biological cells, yet it is still unclear how their morphological structures evolve to regulate their functionality. Co...

    Xusan Yang, Zhigang Yang, Zhaoyang Wu, Ying He, Chunyan Shan in Nature Communications (2020)

  4. No Access

    Article

    Amplified stimulated emission in upconversion nanoparticles for super-resolution nanoscopy

    Super-resolution optical microscopy based on stimulated emission depletion effects can now be performed at much lower light intensities than before by using bright upconversion emission from thulium-doped nano...

    Yujia Liu, Yiqing Lu, Xusan Yang, **anlin Zheng, Shihui Wen, Fan Wang in Nature (2017)

  5. Article

    Open Access

    Three-dimensional controlled growth of monodisperse sub-50 nm heterogeneous nanocrystals

    The ultimate frontier in nanomaterials engineering is to realize their composition control with atomic scale precision to enable fabrication of nanoparticles with desirable size, shape and surface properties. ...

    Deming Liu, **aoxue Xu, Yi Du, **an Qin, Yuhai Zhang, Chenshuo Ma in Nature Communications (2016)