8 Result(s)
within
**njie Pan
Biomedicine
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Article
Open AccessCkip-1 3’UTR alleviates prolonged sleep deprivation induced cardiac dysfunction by activating CaMKK2/AMPK/cTNI pathway
Sleep deprivation (SD) has emerged as a critical concern impacting human health, leading to significant damage to the cardiovascular system. However, the underlying mechanisms are still unclear, and the develo...
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Article
Open AccessRNA m6A methylation regulators in liver cancer
Liver cancer is one of the most common cancers in the world and a primary cause of cancer-related death. In recent years, despite the great development of diagnostic methods and targeted therapies for liver ca...
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Article
Open AccessTemporal-spatial Generation of Astrocytes in the Develo** Diencephalon
Astrocytes are the largest glial population in the mammalian brain. However, we have a minimal understanding of astrocyte development, especially fate specification in different regions of the brain. Through l...
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The diagnostic potential of a circRNA–miRNA network in non-small cell lung cancer
Increasing studies demonstrate the significant contributions of circRNA-related competitive endogenous RNA (ceRNA) regulatory networks to tumorigenesis and cancer progression. Here, we aimed to construct a non...
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Article
Emerging Regulatory Mechanisms of N6-Methyladenosine Modification in Cancer Metastasis
Cancer metastasis is the major cause of cancer-related deaths and accounts for poor therapeutic outcomes. A metastatic cascade is a series of complicated biological processes. N6-methyladenosine (m6A) is the most...
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Article
Open AccessCharacteristics of pre-metastatic niche: the landscape of molecular and cellular pathways
Metastasis is a major contributor to cancer-associated deaths. It involves complex interactions between primary tumorigenic sites and future metastatic sites. Accumulation studies have revealed that tumour met...
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Article
Open AccessConditional knockout of leptin receptor in neural stem cells leads to obesity in mice and affects neuronal differentiation in the hypothalamus early after birth
Leptin, secreted by peripheral adipocytes, binds the leptin receptor (Lepr) in the hypothalamus, thereby contributing to the regulation of satiety and body weight. Lepr is expressed in the embryonic brain as e...
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Article
Near-Infrared Spectroscopy Assay of Key Quality-Indicative Ingredients of Tongkang Tablets
The objective of this paper is to develop an easy and fast near-infrared spectroscopy (NIRS) assay for the four key quality-indicative active ingredients of Tongkang tablets by comparing the true content of th...
