364 Result(s)
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**ning Li
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEvaluating three internal fixation techniques for Pauwels III femoral neck fractures via finite element analysis
The selection of implants for fixing unstable femoral neck fractures (FNF) remains contentious. This study employs finite element analysis to examine the biomechanics of treating Pauwels type III femoral neck ...
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Open AccessA retrospective study of adjuvant albumin-bound paclitaxel plus S-1 after D2 gastrectomy versus oxaliplatin plus S-1 in gastric cancer
Adjuvant oxaliplatin plus S-1 (SOX) chemotherapy for gastric cancer (GC) after D2 gastrectomy has been proven effective. There has yet to be a study that evaluates adjuvant nanoparticle albumin-bound paclitaxe...
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Open AccessRUNX1 regulates MCM2/CDC20 to promote COAD progression modified by deubiquitination of USP31
Colon adenocarcinoma (COAD) is the second leading cause of cancer death, and there is still a lack of diagnostic biomarkers and therapeutic targets. In this study, bioinformatics analysis of the TCGA database ...
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Open AccessHighly accurate carbohydrate-binding site prediction with DeepGlycanSite
As the most abundant organic substances in nature, carbohydrates are essential for life. Understanding how carbohydrates regulate proteins in the physiological and pathological processes presents opportunities...
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Open AccessPredicting ineffective thrombolysis in acute ischemic stroke with clinical and biochemical markers
**Ischemic stroke remains a leading cause of morbidity and mortality globally. Despite the advances in thrombolytic therapy, notably recombinant tissue plasminogen activator (rtPA), patient outcomes are highly...
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Open AccessWavefunction matching for solving quantum many-body problems
Ab initio calculations have an essential role in our fundamental understanding of quantum many-body systems across many subfields, from strongly correlated fermions1–3 to quantum chemistry4–6 and from atomic and ...
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Selective lignin arylation for biomass fractionation and benign bisphenols
Lignocellulose is mainly composed of hydrophobic lignin and hydrophilic polysaccharide polymers, contributing to an indispensable carbon resource for green biorefineries1,2. When chemically treated, lignin is com...
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Open AccessContinuous blood exchange in rats as a novel approach for experimental investigation
Blood exchange therapy, specifically Whole blood exchange (WBE), is increasingly being utilized in clinical settings to effectively treat a range of diseases. Consequently, there is an urgent requirement to es...
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Open AccessHeat-activated growth of metastable and length-defined DNA fibers expands traditional polymer assembly
Biopolymers such as nucleic acids and proteins exhibit dynamic backbone folding, wherein site-specific intramolecular interactions determine overall structure. Proteins then hierarchically assemble into supram...
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Open AccessReduction of precious metal ions in aqueous solutions by contact-electro-catalysis
Precious metals are core assets for the development of modern technologies in various fields. Their scarcity poses the question of their cost, life cycle and reuse. Recently, an emerging catalysis employing co...
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Open AccessFunctional alterations of the brain default mode network and somatosensory system in trigeminal neuralgia
Map** the localization of the functional brain regions in trigeminal neuralgia (TN) patients is still lacking. The study aimed to explore the functional brain alterations and influencing factors in TN patien...
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Open AccessSelective production of methylindan and tetralin with xylose or hemicellulose
Indan and tetralin are widely used as fuel additives and the intermediates in the manufacture of thermal-stable jet fuel, many chemicals, medicines, and shockproof agents for rubber industry. Herein, we disclo...
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Open AccessThe complete assembly of human LAT1-4F2hc complex provides insights into its regulation, function and localisation
The LAT1-4F2hc complex (SLC7A5-SLC3A2) facilitates uptake of essential amino acids, hormones and drugs. Its dysfunction is associated with many cancers and immune/neurological disorders. Here, we apply native ...
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Open AccessOverburden failure and water–sand mixture outburst conditions of weakly consolidated overlying strata in Dananhu No.7 coal mine
This study presents a case of weakly consolidated strata developed in Dananhu No.7 coal mine. Using a combination of numerical simulation, field measurement comparison, and the critical hydraulic gradient crit...
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Open AccessReporting outcome comparisons by sex in oncology clinical trials
Many aspects of human health and disease are influenced by sex as a biological variable and gender as a social construct. A recent study from Nature Communications reported the landscape of outcome comparisions b...
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Open AccessCryo-EM structure of the human Asc-1 transporter complex
The Alanine-Serine-Cysteine transporter 1 (Asc-1 or SLC7A10) forms a crucial heterodimeric transporter complex with 4F2hc (SLC3A2) through a covalent disulfide bridge. This complex enables the sodium-independe...
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Open AccessA prospective phase II clinical trial of total neoadjuvant therapy for locally advanced gastric cancer and gastroesophageal junction adenocarcinoma
To investigate the safety and efficacy of the neoadjuvant chemoradiotherapy (NCRT) followed by neoadjuvant consolidation chemotherapy (NCCT) and surgery for locally advanced gastric cancer (GC) or gastroesopha...
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Open AccessDissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level
Homotypic membrane fusion of the endoplasmic reticulum (ER) is mediated by dynamin-like GTPase atlastin (ATL). This fundamental process relies on GTP-dependent domain rearrangements in the N-terminal region of...
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Open AccessPublisher Correction: Polymer-acid-metal quasi-ohmic contact for stable perovskite solar cells beyond a 20,000-hour extrapolated lifetime
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Open AccessA haplotype-resolved genome provides insight into allele-specific expression in wild walnut (Juglans regia L.)
Wild germplasm resources are crucial for gene mining and molecular breeding because of their special trait performance. Haplotype-resolved genome is an ideal solution for fully understanding the biology of sub...
