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  1. No Access

    Article

    In vitro and in vivo anti-tumor activities of anti-EGFR single-chain variable fragment fused with recombinant gelonin toxin

    Epidermal growth factor receptor (EGFR) plays an important role in the growth and metastasis of many solid tumors. Strategies that target EGFR hold promising therapeutic potential for the treatment for non-sma...

    **kun Zhou, Ji Qiu, Zhen Wang, Nongyu Huang… in Journal of Cancer Research and Clinical On… (2012)

  2. No Access

    Article

    MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer

    Studies have shown that microRNA-148a (miR-148a) was proved to be silenced while DNA methyltransferase 1 (DNMT1) was over-expressed in gastric cancer. But the mechanism of aberrant expression of miR-148a and D...

    Akao Zhu, Jiazeng **a, Junbo Zuo, Shimao **, Hong Zhou, Lubin Yao… in Medical Oncology (2012)

  3. No Access

    Article

    Allogeneic hematopoietic stem cell transplantation overcome the poor prognosis of patients with IKZF1plus CD20–a very high-risk subtype in B-cell acute lymphoblastic leukemia

    Genetic deletions of IKZF1 (IKZF1del) and IKZF1del plus other mutations (IKZF1plus) have been identified in B-cell acute lymphoblastic leukemia (B-ALL) with a poor prognosis. Herein, we investigated the combinati...

    Bingqing Tang, Zihong Cai, Zhixiang Wang, Dainan Lin… in Bone Marrow Transplantation (2022)

  4. Article

    Open Access

    Deciphering tumor-infiltrating dendritic cells in the single-cell era

    Dendritic cells (DCs) serve as a pivotal link connecting innate and adaptive immunity by processing tumor-derived antigens and activating T cells. The advent of single-cell sequencing has revolutionized the ca...

    Qingyu Huang, Fuhao Wang, Di Hao, **nyu Li… in Experimental Hematology & Oncology (2023)

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  5. Article

    Open Access

    Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis

    Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blood vessels. There is increasing evidence that platelets play a crucial role not only in...

    Yanli **, Fangyuan Wang, Jiale Tang, Liying Luo… in Clinical and Experimental Medicine (2024)

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