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  1. Article

    Open Access

    WFDC12-overexpressing contributes to the development of atopic dermatitis via accelerating ALOX12/15 metabolism and PAF accumulation

    Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by eczema-like skin lesions, dry skin, severe itching, and recurrent recurrence. The whey acidic protein four-disulfide core domain g...

    Guolin Li, Linna Gu, Fulei Zhao, Yawen Hu, **aoyan Wang… in Cell Death & Disease (2023)

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  2. Article

    Open Access

    SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction

    Defective execution of proteases and protease inhibitors that mediate abnormal signaling cascades is emerging as a key contributor to skin diseases, such as psoriasis. SerpinB7 is identified as a skin-specific...

    Hua** Zheng, Linna Gu, Fulei Zhao, Chen Zhang, Zhen Wang… in Cell Death & Disease (2022)

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  3. Article

    Open Access

    Emerging role of the Hippo pathway in autophagy

    Autophagy is a dynamic circulatory system that occurs in all eukaryotic cells. Cytoplasmic material is transported to lysosomes for degradation and recovery through autophagy. This provides energy and macromol...

    Dongying Wang, Jiaxing He, Bingyu Huang, Shanshan Liu, Hongming Zhu… in Cell Death & Disease (2020)

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