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Article
Open AccessIGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease with an unknown etiology. RA cannot be fully cured and requires lengthy treatment, imposing a significant burden on both individuals and society. Due t...
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Article
Topological non-reciprocal robust waveguide transport
Devices that surpass the restriction of reciprocity of classical physical waves have brought intriguing possibilities for wave modulation. Non-reciprocal acoustic devices that rely on the viscosity of the medi...
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Article
Open AccessSMAD2 inhibits pyroptosis of fibroblast-like synoviocytes and secretion of inflammatory factors via the TGF-β pathway in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease. Over-activation of fibroblast-like synoviocytes is responsible for the hyperplasia of synovium and destruction of cartilage and bone and ...
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Article
Inhibition of Cdc37 Ameliorates Arthritis in Collagen-Induced Arthritis Rats by Inhibiting Synoviocyte Proliferation and Migration Through the ERK Pathway
Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to synovial inflammation, pannus formation, cartilage damage, bone destruction, and ultimate disability. Fibroblast-like synoviocytes (FL...
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Article
Open AccessTowards precision medicine based on a continuous deep learning optimization and ensemble approach
We developed a continuous learning system (CLS) based on deep learning and optimization and ensemble approach, and conducted a retrospective data simulated prospective study using ultrasound images of breast m...
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Article
Open AccessSurgical Outcomes of Myopic Foveoschisis According to the ATN Classification System
This study compared the surgical outcomes in eyes with myopic foveoschisis (MF) according to the recently developed ATN classification system.
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Chapter and Conference Paper
AssistQ: Affordance-Centric Question-Driven Task Completion for Egocentric Assistant
A long-standing goal of intelligent assistants such as AR glasses/robots has been to assist users in affordance-centric real-world scenarios, such as “how can I run the microwave for 1 min?”. However, there is st...
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Article
Open AccessAssociation of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma
Tongue squamous cell carcinoma (TSCC) ranks as the most prevalent malignancy in the oral cavity. TSCC patients with occult lymph node metastasis (OLNM) are thought to be at risk of worse outcome. However, regu...
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Article
Near-Field Variation of Loudness with Distance
The boundary element method was used to calculate the sound pressure levels at the two ears of an artificial head when a sound source was located in different directions and distances in the near field (within...
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Article
Controllable symmetric caustic beams
We proposed controllable symmetric caustic beams (SCBs), which can follow any desired convex or concave propagation trajectory. The analytical relation between propagation trajectory and phase was constructed ...
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Article
Open AccessBroadband acoustic skin cloak based on spiral metasurfaces
A skin cloak based on the acoustic metasurface made of graded spiral units is proposed and numerically investigated. The presented skin cloak is an acoustical layer consisting of 80 subwavelength-sized unit ce...
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Article
SCY1-Like 1-Binding Protein 1 (SCYL1BP1) Suppressed Sciatic Nerve Regeneration by Enhancing the RhoA Pathway
SCY1-like 1-binding protein 1 (SCYL1BP1) is first identified as an interacting protein with SCYL1. Since SCYL1BP1 is a soluble protein with coiled-coil domains known to be relevant with transcriptional regulat...
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Article
Upregulation of AEG-1 Involves in Schwann Cell Proliferation and Migration After Sciatic Nerve Crush
Astrocyte-elevated gene-1 (AEG-1), also known as metadherin (MTDH) and lysine-rich CEACAM1 coisolated (LYRIC), has emerged as an important oncogene that regulates key cellular processes including apoptosis, mi...
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Article
PCBP2 Modulates Neural Apoptosis and Astrocyte Proliferation After Spinal Cord Injury
PCBP2, a member of the poly(C)-binding protein (PCBP) family, plays a pivotal role in posttranscriptional and translational regulation by interacting with single-stranded poly(C) motifs in target mRNAs. It is ...
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Article
CDK14 Contributes to Reactive Gliosis via Interaction with Cyclin Y in Rat Model of Spinal Cord Injury
Cyclin-dependent kinases (CDKs) are perceived as the engine that drives cell cycle progression whereas cyclins are considered to be the gears that are changed to aid the transition between cycle phases. CDK14 ...
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Article
TCTP Expression After Rat Spinal Cord Injury: Implications for Astrocyte Proliferation and Migration
Translationally controlled tumor protein (TCTP) is a ubiquitous and highly conserved protein which plays a role in cell proliferation and growth, apoptosis, and cell cycle regulation. However, its expression a...
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Article
Up-Regulation of CCT8 Related to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats
Traumatic brain injury (TBI) initiates a series of neurochemical and signaling changes that could eventually lead to neuronal apoptosis. Recent studies indicated that mature neurons cell cycle re-enter played ...
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Article
Nur77 Was Essential for Neurite Outgrowth and Involved in Schwann Cell Differentiation After Sciatic Nerve Injury
Nur77, together with Nurr1 and NOR-1, constitutes the NR4A subgroup of orphan nuclear receptors and plays critical roles in cell proliferation, differentiation, migration, and apoptosis. Among them, Nur77 is u...
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Article
Up-Regulation of HDAC4 is Associated with Schwann Cell Proliferation After Sciatic Nerve Crush
Histone deacetylase 4 (HDAC4), a member of the class IIa HDACs subfamily, has emerged as a critical regulator of cell growth, differentiation, and migration in various cell types. It was reported that HDAC4 st...
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Article
Dependence of binaural loudness summation on interaural level difference and frequency for pure tones
Most of the existing loudness models are based on the diotic listening hypothesis, though human beings always hear in dichotic listening conditions. In this situation, the arithmetic mean of loudness at both e...
