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  1. No Access

    Article

    Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

    Dysfunction of brain resting-state functional networks has been widely reported in psychiatric disorders. However, the causal relationships between brain resting-state functional networks and psychiatric disor...

    Changgai Mu, **nglun Dang, **ong-Jian Luo in Nature Human Behaviour (2024)

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    Article

    Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders

    Anxiety disorders are the most prevalent mental disorders. However, the genetic etiology of anxiety disorders remains largely unknown. Here we conducted a genome-wide meta-analysis on anxiety disorders by incl...

    Wenqiang Li, Rui Chen, Laipeng Feng, **nglun Dang, Jiewei Liu… in Nature Human Behaviour (2024)

  3. No Access

    Article

    Proteome-wide Mendelian randomization reveals the causal effects of immune-related plasma proteins on psychiatric disorders

    Immune dysregulation has been consistently reported in psychiatric disorders, however, the causes and mechanisms underlying immune dysregulation in psychiatric disorders remain largely unclear. Here we conduct...

    **nglun Dang, Meng Song, Luxian Lv, Yongfeng Yang, **ong-Jian Luo in Human Genetics (2023)

  4. No Access

    Article

    Mendelian Randomization Study Using Dopaminergic Neuron-Specific eQTL Identifies Novel Risk Genes for Schizophrenia

    Multiple integrative studies have been performed to identify the potential target genes of the non-coding schizophrenia (SCZ) risk variants. However, all the integrative studies used expression quantitative tr...

    **nglun Dang, Jiewei Liu, Zhijun Zhang, **ong-Jian Luo in Molecular Neurobiology (2023)

  5. Article

    Open Access

    The schizophrenia-associated missense variant rs13107325 regulates dendritic spine density

    The missense variant rs13107325 (C/T, p.Ala391Thr) in SLC39A8 consistently showed robust association with schizophrenia in recent genome-wide association studies (GWASs), suggesting the potential pathogenicity of...

    Shiwu Li, Changguo Ma, Yifan Li, Rui Chen, Yixing Liu… in Translational Psychiatry (2022)

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