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Gamma-glutamyltransferase of Helicobacter pylori alters the proliferation, migration, and pluripotency of mesenchymal stem cells by affecting metabolism and methylation status

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  1. Article

    Open Access

    Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2

    Our previous study found that bone marrow-derived mesenchymal stem cells (BMSCs) promote Helicobacter pylori (H pylori)-associated gastric cancer (GC) progression by secreting thrombospondin-2 (THBS2). Extracellu...

    Cuihua Qi, Huiying Shi, Mengke Fan, Weigang Chen in Cell Communication and Signaling (2023)

  2. Article

    Open Access

    L-Fucose promotes enteric nervous system regeneration in type 1 diabetic mice by inhibiting SMAD2 signaling pathway in enteric neural precursor cells

    Diabetes can lead to extensive damage to the enteric nervous system (ENS), causing gastrointestinal motility disorders. However, there is currently a lack of effective treatments for diabetes-induced ENS damag...

    Hailing Yao, Huiying Shi, Chen Jiang, Mengke Fan in Cell Communication and Signaling (2023)

  3. Article

    Open Access

    A novel TF molecular switch-mechanism found in two contrasting ecotypes of a psammophyte, Agriophyllum squarrosum, in regulating transcriptional drought memory

    Prior drought stress may change plants response patterns and subsequently increase their tolerance to the same condition, which can be referred to as “drought memory” and proved essential for plants well-being...

    Tingzhou Fang, Chaoju Qian, Bachir Goudia Daoura, **a Yan, **ngke Fan in BMC Plant Biology (2023)

  4. Article

    Open Access

    Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation

    There is a lack of effective therapies for enteric nervous system (ENS) injury. Our previous study showed that transplanted bone marrow-derived mesenchymal stem cells (BMSCs) play a “glia-like cells” role in i...

    Mengke Fan, Huiying Shi, Hailing Yao, Weijun Wang in Stem Cell Research & Therapy (2022)

  5. Article

    Open Access

    Eradication of Helicobacter pylori alleviates lipid metabolism deterioration: a large-cohort propensity score-matched analysis

    The impact of Helicobacter pylori (H. pylori) eradication on metabolism of lipid and the potential predictor of such changes remain unclear.

    Zeyu Wang, Weijun Wang, Rui Gong, Hailing Yao, Mengke Fan in Lipids in Health and Disease (2022)

  6. Article

    Open Access

    Development of highly polymorphic simple sequence repeat markers using genome-wide microsatellite variant analysis in Foxtail millet [Setaria italica (L.) P. Beauv.]

    Foxtail millet (Setaria italica (L.) Beauv.) is an important gramineous grain-food and forage crop. It is grown worldwide for human and livestock consumption. Its small genome and diploid nature have led to foxta...

    Shuo Zhang, Chanjuan Tang, Qiang Zhao, **g Li, Lifang Yang, Lufeng Qie in BMC Genomics (2014)