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Article
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models
Autophagy impairment is a key factor in Alzheimer’s disease (AD) pathogenesis. TFEB (transcription factor EB) and TFE3 (transcription factor binding to IGHM enhancer 3) are nuclear transcription factors that r...
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Article
Open AccessDeficiency of neutral cholesterol ester hydrolase 1 (NCEH1) impairs endothelial function in diet-induced diabetic mice
Neutral cholesterol ester hydrolase 1 (NCEH1) plays a critical role in the regulation of cholesterol ester metabolism. Deficiency of NCHE1 accelerated atherosclerotic lesion formation in mice. Nonetheless, the...
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Article
A novel prognostic model to predict mortality in patients with acute-on-chronic liver failure in intensive care unit
Acute-on-chronic liver failure (ACLF) implies high short-term mortality rates and usually requires intensive care unit (ICU) admission. Proper prognosis for these patients is crucial for early referral for liv...
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Chapter and Conference Paper
Rates Optimization of CO2 Huff and Puff in Multi-stage Fracturing Horizontal Wells Based on Proximal Policy Optimization Algorithm
CO2 huff and puff is an important replacement method for the subsequent improvement of oil recovery after the elastic development of multi-stage fracturing horizontal wells in tight reservoirs. The rates optimiza...
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Article
Species diversity and related ecology of chiggers on small mammals in a unique geographical area of Yunnan Province, southwest China
Chiggers are common ectoparasites and the exclusive vector of scrub typhus. Based on previous investigations from a unique geographical area in Yunnan Province of southwest China, the Three Parallel Rivers Are...
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Article
Open AccessTight finite-key analysis for mode-pairing quantum key distribution
Mode-pairing quantum key distribution (MP-QKD) is a potential protocol that is not only immune to all possible detector side channel attacks, but also breaks the repeaterless rate-transmittance bound without n...
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Article
Open AccessA parabrachial-hypothalamic parallel circuit governs cold defense in mice
Thermal homeostasis is vital for mammals and is controlled by brain neurocircuits. Yet, the neural pathways responsible for cold defense regulation are still unclear. Here, we found that a pathway from the lat...
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Article
Receiver function imaging of dense seismic array and deep dynamic mechanism beneath the eastern South China
The Mesozoic tectonic framework of the eastern South China is mainly controlled by subduction, turning toward, and rollback of the Pacific Plate. Recent studies of receiver function imaging and ambient noise t...
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Article
Infestation and distribution of chigger mites on Confucian white-bellied rat (Niviventer confucianus) in Southwest China
Based on the field investigation in five provincial regions of Southwest China between 2001 and 2019, the present paper reports the infestation and distribution of chigger mites on the Confucian white-bellied ...
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Article
A research review of experimental animal models with myelodysplastic syndrome
Myelodysplastic syndrome (MDS) consists of a group of hematologic tumors that are derived from the clonal proliferation of hematopoietic stem cells, featuring abnormal hematopoietic cell development and ineffe...
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Article
A chemiresistive biosensor for detection of cancer biomarker in biological fluids using CVD-grown bilayer graphene
A chemiresistive biosensor is described for simple and selective detection of miRNA-21. We developed chemical vapor deposition (CVD) and low-damage plasma treatment (LDPT)-treated bilayer graphene composite o...
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Article
Population-attributable fractions of risk factors for all-cause dementia in China rural and urban areas: a cross-sectional study
The prevalence of dementia in China, particularly in rural areas, is consistently increasing; however, research on population-attributable fractions (PAFs) of risk factors for dementia is scarce.
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Article
IRAK2-NF-κB signaling promotes glycolysis-dependent tumor growth in pancreatic cancer
Metabolic reprogramming has emerged as a core hallmark of cancer, and cancer metabolism has long been equated with aerobic glycolysis. Moreover, hypoxia and the hypovascular tumor microenvironment (TME) are ma...
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Article
Effect of polypropylene fiber and coarse aggregate on the ductility and fluidity of cemented tailings backfill
Adding polypropylene (PP) fibers and coarse aggregates has become a popular way to enhance the strength and stability of the cemented tailings backfilling (CTB) body. It is essential to explore the influence o...
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Article
Infestation and distribution of mites on the Yunnan red-backed vole (Eothenomys miletus) in Yunnan Province of southwest China between 2001 and 2015
The Yunnan red-backed vole (Eothenomys miletus) is an endemic rodent species in China and it often harbors two groups of mites, chigger mites and gamasid mites, on its body surface. A few species of chigger mites...
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Article
Long-term outcome of liver complications in patients with chronic HBV/HCV co-infection after antiviral therapy: a real-world nationwide study on Taiwanese Chronic Hepatitis C Cohort (T-COACH)
The long-term outcome of hepatitis B virus (HBV) infection among patients dually infected with HBV and hepatitis C virus (HCV) remains unclear. We aimed to investigate the long-term liver outcomes of HBV/HCV-c...
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Article
Aquamicrobium zhengzhouense sp. nov., a Bacterium Isolated from Farmland Soil Applied with Amino Acid Fertilizer
A novel Gram-stain-negative, rod-shaped, strictly aerobic, non-motile bacterium, designated strain cd-1T, was isolated from a farmland soil applied with amino acid fertilizer in Zhengzhou, Henan province, China. ...
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Article
Commissioning experiences with the spoke-based CW superconducting proton linac
The 10-MeV Accelerator-Driven Subcritical (ADS) system Injector-I test stand at the Institute of High Energy Physics (IHEP) is a testing facility dedicated to demonstrating the feasibility of the spoke-based s...
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Article
Open AccessTight finite-key analysis for quantum key distribution without monitoring signal disturbance
Unlike traditional communication, quantum key distribution (QKD) can reach unconditional security and thus attracts intensive studies. Among all existing QKD protocols, round-robin-differential-phase-shift (RR...
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Article
Infestation and distribution of gamasid mites on Himalayan field rat (Rattus nitidus) in Yunnan Province of Southwest China
Besides being an important pest in agriculture and forestry, the Himalayan field rat (Rattus nitidus) can be the reservoir host of many zoonoses. Some ectoparasitic gamasid mites on rodents (rats, mice and voles,...
