648 Result(s)

Article

Correction to: Exogenous Adenosine Antagonizes Excitatory Amino Acid Toxicity in Primary Astrocytes

Yingjiao Liu, Shifeng Chu, Yaomei Hu, Songwei Yang… in Cellular and Molecular Neurobiology (2024)

Article

Benmelstobart, anlotinib and chemotherapy in extensive-stage small-cell lung cancer: a randomized phase 3 trial

Immunochemotherapy is the first-line standard for extensive-stage small-cell lung cancer (ES-SCLC). Combining the regimen with anti-angiogenesis may improve efficacy. ETER701 was a multicenter, double-blind, r...

Ying Cheng, Jianhua Chen, Wei Zhang, Chao **e, Qun Hu, Ningning Zhou… in Nature Medicine (2024)

Article

Nicotinamide riboside restores nicotinamide adenine dinucleotide levels and alleviates brain injury by inhibiting oxidative stress and neuroinflammation in a mouse model of intracerebral hemorrhage

Hemorrhagic stroke is a global health problem owing to its high morbidity and mortality rates. Nicotinamide riboside is an important precursor of nicotinamide adenine dinucleotide characterized by a high bioav...

**g She, Hua Zhang, Hui Xu, Yan-Yan Li, Jun-Chao Wu, Rong Han… in Molecular Neurobiology (2024)

Article

Systematic Mendelian Randomization Exploring Druggable Genes for Hemorrhagic Strokes

Patients with hemorrhagic stroke have high rates of morbidity and mortality, and drugs for prevention are very limited. Mendelian randomization (MR) analysis can increase the success rate of drug development b...

Lun-Zhe Yang, Yong Yang, Chuan Hong, Qi-Zhe Wu, **ong-Jie Shi… in Molecular Neurobiology (2024)

Article

Correction: Rotenone Could Activate Microglia Through NFκB Associated Pathway

Yu-he Yuan, Jian-dong Sun, Miao-miao Wu, **-feng Hu… in Neurochemical Research (2024)

Article

Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway

The microglia-mediated neuroinflammation have been shown to play a crucial role in the ocular pathological angiogenesis process, but specific immunotherapies for neovascular ocular diseases are still lacking. ...

Biyan Ni, Ziqi Yang, Tian Zhou, Hong Zhou, Yang Zhou… in Journal of Neuroinflammation (2024)

Article

Author Correction: A shifting role of thalamocortical connectivity in the emergence of cortical functional organization

Shinwon Park, Koen V. Haak, Stuart Oldham, Hanbyul Cho… in Nature Neuroscience (2024)

Article

A Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex

This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease phenotypes, which has not been depicted by the known neurodegenerative...

Han-Kui Liu, Hong-Lin Hao, Hui You, Feng Feng, **u-Hong Qi… in Neuroscience Bulletin (2024)

Article

Autism spectrum disorders detection based on multi-task transformer neural network

Autism Spectrum Disorders (ASD) are neurodevelopmental disorders that cause people difficulties in social interaction and communication. Identifying ASD patients based on resting-state functional magnetic reso...

Le Gao, Zhimin Wang, Yun Long, **n Zhang, Hexing Su, Yong Yu, ** Hong in BMC Neuroscience (2024)

Article

Protein Disulfide Isomerase Endoplasmic Reticulum Protein 57 (ERp57) is Protective Against ALS-Associated Mutant TDP-43 in Neuronal Cells

Amyotrophic Lateral Sclerosis (ALS) is a severe neurodegenerative disease affecting motor neurons. Pathological forms of Tar-DNA binding protein-43 (TDP-43), involving its mislocalisation to the cytoplasm and ...

Sonam Parakh, Emma R. Perri, Marta Vidal, Zeinab Takalloo… in NeuroMolecular Medicine (2024)

Article

Sustained aviremia despite anti-retroviral therapy non-adherence in male children after in utero HIV transmission

After sporadic reports of post-treatment control of HIV in children who initiated combination anti-retroviral therapy (cART) early, we prospectively studied 284 very-early-cART-treated children from KwaZulu-Na...

Nomonde Bengu, Gabriela Cromhout, Emily Adland, Katya Govender… in Nature Medicine (2024)

Article

Automated, IMU-based spine angle estimation and IMU location identification for telerehabilitation

Telerehabilitation is a promising avenue for improving patient outcomes and expanding accessibility. However, there is currently no spine-related assessment for telerehabilitation that covers multiple exercises.

Huiming Pan, Hong Wang, Dongxuan Li… in Journal of NeuroEngineering and Rehabilita… (2024)

Article

Vedolizumab for the prevention of intestinal acute GVHD after allogeneic hematopoietic stem cell transplantation: a randomized phase 3 trial

Acute graft-versus-host disease (aGVHD) of the lower gastrointestinal (GI) tract is a major cause of morbidity and mortality in patients receiving allogeneic hematopoietic stem cell transplantation (allo-HSCT)...

Yi-Bin Chen, Mohamad Mohty, Robert Zeiser, Takanori Teshima, Omer Jamy… in Nature Medicine (2024)

Article

Attentional impairment and altered brain activity in healthcare workers after mild COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is highly transmissible and pathogenic. Patients with mild cases account for the majority of those infected with coronavirus disease 2019 (COVID-19)...

Keyi Lin, Yaotian Gao, Wei Ji, Yan Li, Wei Wang, Mengcheng Du… in Brain Imaging and Behavior (2024)

Article

Tanshinone IIA is superior to paricalcitol in ameliorating tubulointerstitial fibrosis through regulation of VDR/Wnt/β-catenin pathway in rats with diabetic nephropathy

Glomerulosclerosis and tubulointerstitial fibrosis (TIF) are closely involved in the development of diabetic nephropathy (DN). Moreover, the development of TIF is closely related to epithelial-to-mesenchymal t...

**g-Yi Zeng, Yu Wang, Fu-Yuan Hong… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

Article

Association between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer

Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but fe...

Yue Zeng, Chun-Hong Hu, Yi-Zheng Li, Jian-Song Zhou, Shu-**ng Wang… in Nature Medicine (2024)

Article

MiR-184 Mediated the Expression of ZNF865 in Exosome to Promote Procession in the PD Model

Exosomes are nanoscale small vesicles (EVs) secreted by cells that carry important bio information, including proteins, miRNAs, and more. Exosome contents are readily present in body fluids, including blood, a...

Chang Liu, Yang Wang, **g-wen Li, **aoyan Zhu, Hai-song Jiang… in Molecular Neurobiology (2024)

Article

Current advances and future trends of hormesis in disease

Hormesis, an adaptive response, occurs when exposure to low doses of a stressor potentially induces a stimulatory effect, while higher doses may inhibit it. This phenomenon is widely observed across various or...

Yantong Wan, **xi Liu, Yiyin Mai, Yinghao Hong, Zixuan Jia, Guijie Tian… in npj Aging (2024)

Article

Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study

This study aimed to unveil the central mechanism of moxibustion treating chronic inflammatory visceral pain (CIVP) from the angle of circRNA-miRNA-mRNA networks in the spinal cord. The rat CIVP model was estab...

Dan Zhang, **aoqing Dong, **aoying Li, Yanting Yang, Hongna Li, Yue Hong… in Molecular Brain (2024)

Article

Effect of task-oriented training assisted by force feedback hand rehabilitation robot on finger gras** function in stroke patients with hemiplegia: a randomised controlled trial

Over 80% of patients with stroke experience finger gras** dysfunction, affecting independence in activities of daily living and quality of life. In routine training, task-oriented training is usually used fo...

Yinghua Li, Yawen Lian, **aowei Chen… in Journal of NeuroEngineering and Rehabilita… (2024)