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Article
Effects of Vitamin D Supplementation on Cognitive Outcomes: A Systematic Review and Meta-Analysis
Clinical studies examining the effects of vitamin D on cognition have reported inconsistent results. To date, no comprehensive study has examined this effect on the basis of sample characteristics or intervent...
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Article
Comparison of endoscopic third ventriculostomy versus cerebrospinal fluid shunt procedures for the treatment of pediatric hydrocephalus in Taiwan
Pediatric hydrocephalus is the most common cause of surgically treatable neurological disease in children. Controversies exist whether endoscopic third ventriculostomy (ETV) or cerebrospinal fluid (CSF) shunt ...
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Article
Open AccessSkin mottling score assesses peripheral tissue hypoperfusion in critically ill patients following cardiac surgery
Skin mottling is a common manifestation of peripheral tissue hypoperfusion, and its severity can be described using the skin mottling score (SMS). This study aims to evaluate the value of the SMS in detecting ...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Open AccessExploring the multifaceted roles of mathematics learning in predicting students' computational thinking competency
There exist shared competencies between computational thinking (CT) and mathematics, and these two domains also mutually benefit from various teaching approaches. However, the linkages between mathematics and ...
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Article
Open AccessEffects of dysregulated glucose metabolism on the occurrence and ART outcome of endometriosis
Endometriosis is associated with systemic metabolic indicators, including body mass index (BMI), glucose metabolism and lipid metabolism, while the association between metabolic indexes and the occurrence and ...
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Article
Open AccessIn vitro studies of factors affecting debridement of dental implants by tricalcium phosphate powder abrasive treatment
Peri-implantitis is a common complication characterized by inflammation in tissues surrounding dental implants due to plaque accumulation, which can lead to implant failure. While air flow abrasive treatment h...
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Article
Open AccessPostoperative glucocorticoids in patients with acute type A aortic dissection (GLAD): study protocol for a prospective, single-center, randomized controlled trial
Patients receiving surgical treatment of acute type A Aortic Dissection (aTAAD) are common to suffer organ dysfunction in the intensive care unit due to overwhelming inflammation. Previous studies have reveale...
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Article
Open AccessCorrection: Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage
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Article
Open AccessPopulation genomic analysis provides evidence of the past success and future potential of South China tiger captive conservation
Among six extant tiger subspecies, the South China tiger (Panthera tigris amoyensis) once was widely distributed but is now the rarest one and extinct in the wild. All living South China tigers are descendants of...
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Article
Open AccessExtracellular vesicles derived from CD4+ T cells carry DGKK to promote sepsis-induced lung injury by regulating oxidative stress and inflammation
Sepsis is an abnormal immune response after infection, wherein the lung is the most susceptible organ to fail, leading to acute lung injury. To overcome the limitations of current therapeutic strategies and de...
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Article
Classifying Temporomandibular Disorder with Artificial Intelligent Architecture Using Magnetic Resonance Imaging
This study proposes a new diagnostic tool for automatically extracting discriminative features and detecting temporomandibular joint disc displacement (TMJDD) accurately with artificial intelligence. We analyz...
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Article
Open AccessTransarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)
There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC...
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Article
Open AccessTerminally ill patients’ and their relatives’ experiences and behaviors regarding complementary and alternative medicine utilization in hospice palliative inpatient care units: a cross-sectional, multicenter survey
Terminally ill patients often experience exacerbations of diseases that render mainstream medicine ineffective in relieving symptoms, prompting attempts at complementary and alternative medicine (CAM). This st...
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Malignant Neoplasms of the Small Intestines
Malignant neoplasms are very rare disease regardless of primary or secondary. The diagnosis of small intestine malignant tumor is challenging. In this chapter, the authors presented various malignant diseases ...
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Article
Open AccessCpG-binding protein CFP1 promotes ovarian cancer cell proliferation by regulating BST2 transcription
Epigenetic alterations have been functionally linked to ovarian cancer development and occurrence. The CXXC zinc finger protein 1 (CFP1) is an epigenetic regulator involved in DNA methylation and histone modif...
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Article
Enantiomeric Phenylpropanoids from Uncaria rhynchophylla
Pairs of enantiomeric phenylpropanoid glycosides and their aglycones, (8R)-stroside A (1), (8S)-stroside A (2), (8R)-evofolin B (3), and (8S)-evofolin B (4), were isolated from the hook-bearing stems of Uncaria r...
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Article
Open AccessSpinal cord injury and spinal fracture in patients with ankylosing spondylitis
Spinal cord injury (SCI) and spinal fracture are major complications in patients with ankylosing spondylitis (AS) who sustain spinal trauma. The purpose of this study was to investigate the incidence, predicto...
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Article
Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis
Dysregulation of pericellular proteolysis is strongly implicated in cancer metastasis through alteration of cell invasion and the microenvironment. Matriptase-2 (MT-2) is a membrane-anchored serine protease wh...
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Article
Open AccessGenomes of leafy and leafless Platanthera orchids illuminate the evolution of mycoheterotrophy
To improve our understanding of the origin and evolution of mycoheterotrophic plants, we here present the chromosome-scale genome assemblies of two sibling orchid species: partially mycoheterotrophic Platanthera ...
