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1,720 Result(s)
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Open AccessCorrection: Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice
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Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus
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Open AccessPopulation structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert
Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental adaptability, enhancing breeding efficiency, and achieving effec...
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Low-temperature atomic-level trimming on Ge interfused surface for gate-all-around Si nanosheets transistors
In order to effectively remove the residual Ge atoms at the surface of channel and improve the interfacial characteristic of gate-all-around (GAA) Si nanosheet field effect transistors, a low-temperature atomi...
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Open AccessPlastome evolution of Engelhardia facilitates phylogeny of Juglandaceae
Engelhardia (Juglandaceae) is a genus of significant ecological and economic importance, prevalent in the tropics and subtropics of East Asia. Although previous efforts based on multiple molecular markers providi...
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Effect of carbon concentration on melting behavior of steel scraps in hot metal baths
To reveal the intricate mechanisms underlying the melting and dissolution processes of scraps in the iron ladle, the melting characteristics of three carbon steels with different C concentrations at the bath t...
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Open AccessSimultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients
Simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) is an innovative technique delivering a higher dose to the tumor bed while irradiating the entire breast. This study aims to assess the...
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Open AccessCRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer
Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for many types of cancer. Here we systematically identify genetic drivers underlying chemoresistance by performing 30 genome-...
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Open AccessNicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...
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The p38/MAPK pathway as a therapeutic target to prevent therapeutic escape of breast cancer stem cells
Cancer stem cells (CSCs) play an important role in metastasis development, tumor recurrence, and treatment resistance, and are essential for the eradication of cancer. Currently, therapies fail to eradicate CS...
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DeepPollenCount: a swin-transformer-YOLOv5-based deep learning method for pollen counting in various plant species
Accurate identification and quantification of pollens (e.g., pollen of a flower, airborne pollens) is essential to understand plant pollination and reproductive biology, pollen aerobiology, and plant–insect in...
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Integrative Analysis of the Microbiome and Metabolome of Broiler Intestine: Insights into the Mechanisms of Probiotic Action as an Antibiotic Substitute
Antibiotic substitutes have become a research focus due to restrictions on antibiotic usage. Among the antibiotic substitutes on the market, probiotics have been extensively researched and used. However, the m...
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Prenatal ultrasonic diagnosis of esophageal atresia and tracheoesophageal fistula combined with interrupted inferior vena cava: a rare case report
This is an extremely rare case of complicated fetal esophageal atresia (EA) with tracheoesophageal fistula (TEF) and interrupted inferior vena cava (IVC) diagnosed by prenatal ultrsonography and successfully t...
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Evaluation of combined epiretinal membrane removal with intravitreal triamcinolone injection utilizing ectopic inner foveal layer staging scheme
To investigate the macular morphological and visual outcomes of combined idiopathic epiretinal membrane (iERM) removal with triamcinolone acetonide (TA) injection based on consideration of the ectopic inner fo...
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Open AccessA N–CoSe/CoSe2–C@Cu hierarchical architecture as a current collector-integrated anode for potassium-ion batteries
The highly reversible insertion/extraction of large-radius K+ into electrode materials remains a tough goal, especially for conversion-type materials. Herein, we design a current collector-integrated electrode (N...
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Seawater-based soybean urease for calcareous sand biomineralization
In tropical islands, calcareous sand with poor engineering properties usually needs to be treated before it can be used as building materials. Considering the scarcity of freshwater in these areas, this study ...
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Synergistic rare-earth yttrium single atoms and copper phosphide nanoparticles for high-selectivity ammonia electrosynthesis
Electrochemical nitrate reduction to NH3 holds a great promise for N-upcycling in nature, while its sluggish reaction kinetics involved in both the stepwise deoxygenation and hydrogenation processes necessitates ...
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Open AccessTMC6 functions as a GPCR-like receptor to sense noxious heat via Gαq signaling
Thermosensation is vital for the survival, propagation, and adaption of all organisms, but its mechanism is not fully understood yet. Here, we find that TMC6, a membrane protein of unknown function, is highly ...
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Open AccessAKI-Pro score for predicting progression to severe acute kidney injury or death in patients with early acute kidney injury after cardiac surgery
No reliable clinical tools exist to predict acute kidney injury (AKI) progression. We aim to explore a scoring system for predicting the composite outcome of progression to severe AKI or death within seven day...
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A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...