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  1. Article

    Open Access

    Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma

    Tumour lineage plasticity is an emerging hallmark of aggressive tumours. Tumour cells usually hijack developmental signalling pathways to gain cellular plasticity and evade therapeutic targeting. In the presen...

    Wei Cheng, Hao-Long Li, Shao-Yan **, **ao-Feng Zhang, Yun Zhu in Nature Communications (2021)

  2. Article

    Open Access

    Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

    RNA editing and splicing are the two major processes that dynamically regulate human transcriptome diversity. Despite growing evidence of crosstalk between RNA editing enzymes (mainly ADAR1) and splicing machi...

    Sze **g Tang, Haoqing Shen, Omer An, HuiQi Hong, Jia Li in Nature Communications (2020)

  3. Article

    Open Access

    Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

    Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chr...

    Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui in Nature Communications (2018)

  4. Article

    Open Access

    Short-term Effects of Risperidone Monotherapy on Spontaneous Brain Activity in First-episode Treatment-naïve Schizophrenia Patients: A Longitudinal fMRI Study

    It is unclear whether abnormal spontaneous neural activation patterns found in chronic schizophrenia patients (CSP) are part of the pathogenesis of disease, consequences of chronic illness, or effects of antip...

    Mao-Lin Hu, **ao-Fen Zong, Jun-Jie Zheng, Spiro P. Pantazatos in Scientific Reports (2016)

  5. Article

    Open Access

    The surface structure of silver-coated gold nanocrystals and its influence on shape control

    Understanding the surface structure of metal nanocrystals with specific facet indices is important due to its impact on controlling nanocrystal shape and functionality. However, this is particularly challengin...

    J. Daniel Padmos, Michelle L. Personick, Qing Tang in Nature Communications (2015)