4,392 Result(s)
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**n-Yu Wang
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Novel Synthesis of CuW Composite Containing Micro- and Nano-tungsten Particles Coated with SixWy Phase via Silicothermic Coupling with Aluminothermic Reduction
A novel method for preparing CuW composite containing micro- and nano-tungsten particles coated with SixWy phase via silicothermic coupling with aluminothermic reduction is presented in this paper. Compared with ...
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Article
Open AccessNotoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...
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Open AccessSpray pyrolysis-derived W-doped MoSe2/rGO paper-like microspheres: optimization of microstructure and mesostructure for enhanced lithium storage
Two-dimensional MoSe2 is a promising candidate for lithium-ion battery anodes. However, its conductivity and lithium storage volumetric effect still need to be optimized. In this work, W-doped MoSe2/rGO paper-lik...
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Recent advances in Ir/Ru-based perovskite electrocatalysts for oxygen evolution reaction
Oxygen evolution reaction (OER) is a kinetically harsh four-electron anode reaction that requires a large overpotential to provide current and is of great importance in renewable electrochemical technique. Ir/...
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Improvement in corrosion resistance of Mg97Zn1Y2 alloy by Zr addition
Magnesium alloys, known for their exceptional lightweight properties, have presented challenges in various applications due to their limited corrosion resistance. In this study, the corrosion resistance of Mg97Zn
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Study on the NHAP-PMEDM-milling process of 316 L steel
316 L steel-based human implants play an important role in the biomedical field. In order to address the problem of immune rejection of 316 L steel-based human implants and further improve the machining effici...
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Article
Open AccessSub-seasonal prediction skill: is the mean state a good model evaluation metric?
Evaluating forecast models encompasses assessing their ability to accurately depict observed climate states and predict future climate variables. Various evaluation methods, from computationally efficient meas...
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Open AccessAssociation of smoking cessation patterns and untreated smoking with glaucoma, cataract, and macular degeneration: a population-based retrospective study
This study aims to assess the association between nicotine replacement therapy (NRT), varenicline, and untreated smoking with the risk of develo** eye disorders. We employed a new-user design to investigate ...
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An Improved Grey Relational Theory Evaluation Method: Considering the Comprehensive Performance of Autonomous Vehicles in Virtual Test
Reasonable test scenarios and objective evaluation methods can rapidly promote the development of autonomous vehicle technology. A new quantitative evaluation method for the comprehensive performance of autono...
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Article
Open AccessQualitative study on the perception of good death in patients with end-stage cancer in oncology nurses
To explore the perception of good death of patients with end-stage cancer by nurses in the oncology department.
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Article
Inflammation-Responsive Mesoporous Silica Nanoparticles with Synergistic Anti-inflammatory and Joint Protection Effects for Rheumatoid Arthritis Treatment
Joint destruction is a major burden and an unsolved problem in rheumatoid arthritis (RA) patients. We designed an intra-articular mesoporous silica nanosystem (MSN-TP@PDA-GlcN) with anti-inflammatory and joint...
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Article
Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Article
Two new aromatic tenvermectins from mutant Streptomyces avermitilis HU02-06
Two new aromatic tenvermectins (TVMs), 13-oleandrosyl-oleandrosyloxy ST906 (1) and aromatic TVM B (2), were isolated from the fermentation broth of Streptomyces avermitilis HU02-06. Their structures were establis...
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Article
Metal-slag separation strengthening through in situ slagging during CuW composite preparation by metallothermic reduction
CuW is widely used in high-voltage electrical switch contacts, rocket nozzle throat linings, electronic packaging materials and other major high-end technologies. CuW is typically fabricated using infiltration...
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Open AccessDietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism
Mediterranean diet rich in polyphenolic compounds holds great promise to prevent and alleviate multiple sclerosis (MS), a central nervous system autoimmune disease associated with gut microbiome dysbiosis. Hea...
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Probing electrolyte effects on cation-enhanced CO2 reduction on copper in acidic media
Tuning the properties of the electric double layer via cations is a recognized approach for improving the efficiency of the CO2 reduction reaction (CO2RR). However, the mechanism behind cation-enhanced CO2RR kine...
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Article
Open AccessA comprehensive workflow for optimizing RNA-seq data analysis
Current RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering species-specific differences. However, the suitability and accuracy of these tool...
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Machine-learning-aided Au-based single-atom alloy catalysts discovery for electrochemical NO reduction reaction to NH3
Direct electrochemical conversion of NO to NH3 has attracted widespread interest as a green and sustainable strategy for both ammonia synthesis and nitric oxide removal. However, designing efficient catalysts rem...
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Open AccessIdentification of lipid-modifying drug targets for autoimmune diseases: insights from drug target mendelian randomization
A growing body of evidence has highlighted the interactions of lipids metabolism and immune regulation. Nevertheless, there is still a lack of evidence regarding the causality between lipids and autoimmune dis...
