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  1. Article

    Open Access

    A SARS-CoV-2-specific CAR-T-cell model identifies felodipine, fasudil, imatinib, and caspofungin as potential treatments for lethal COVID-19

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced cytokine storm is closely associated with coronavirus disease 2019 (COVID-19) severity and lethality. However, drugs that are effective agai...

    Lin **a, Lun-zhi Yuan, Ya-hong Hu, Jun-yi Liu… in Cellular & Molecular Immunology (2023)

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    Article

    Construction of a sustainable 3-hydroxybutyrate-producing probiotic Escherichia coli for treatment of colitis

    Colitis is a common disease of the colon that is very difficult to treat. Probiotic bacteria could be an effective treatment. The probiotic Escherichia coli Nissle 1917 (EcN) was engineered to synthesize the keto...

    Xu Yan, **n-Yi Liu, Dian Zhang, Yu-Dian Zhang, Zi-Hua Li… in Cellular & Molecular Immunology (2021)

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    Article

    BCR–ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells

    The advent of tyrosine kinase inhibitor (TKI) therapy markedly improved the outcome of patients with chronic-phase chronic myeloid leukemia (CML). However, the poor prognosis of patients with advanced-phase CM...

    Norihiro Ueda, Rong Zhang, Minako Tatsumi, Tian-Yi Liu… in Cellular & Molecular Immunology (2018)