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  1. Article

    Open Access

    Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

    Hybrid map** is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai...

    Jian** Quan, Ming Yang, **ngwang Wang, Gengyuan Cai in Nature Communications (2024)

  2. No Access

    Article

    Z-scheme Bi4O5Br2/NH2-MIL-125(Ti) heterojunctions enable exceptional visible photocatalytic degradation of organic pollutant

    One key strategy to enhance photocatalytic performance is to improve the transfer and separation efficiency of photogenerated carriers by building optimized heterojunctions. Herein, novel Bi4O5Br2/NH2-MIL-125(Ti)...

    Feng Huang, Muhammad Humayun, Gang Li, Ting-Ting Fan, Wen-Lin Wang in Rare Metals (2024)

  3. Article

    Open Access

    Spray pyrolysis-derived W-doped MoSe2/rGO paper-like microspheres: optimization of microstructure and mesostructure for enhanced lithium storage

    Two-dimensional MoSe2 is a promising candidate for lithium-ion battery anodes. However, its conductivity and lithium storage volumetric effect still need to be optimized. In this work, W-doped MoSe2/rGO paper-lik...

    Wei Wang, Jun-Yu Chen, Jie Ouyang, Hong Yin, Ao-Jie Li, Liang Chen in Rare Metals (2024)

  4. No Access

    Article

    Dynamic change of metabolic dysfunction-associated steatotic liver disease in patients with hepatitis C virus infection after achieving sustained virologic response with direct-acting antivirals

    Information on the dynamics of metabolic dysfunction-associated steatotic liver disease (MASLD) among hepatitis C virus patients achieving sustained virologic response (SVR12) with direct-acting antivirals (DAAs)...

    Chen-Hua Liu, Yu-** Chang, Yu-Jen Fang, Pin-Nan Cheng in Journal of Gastroenterology (2024)

  5. No Access

    Article

    LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo

    Long noncoding RNAs (lncRNAs) have been demonstrated to participate in neuroblastoma cisplatin resistance and tumorigenesis. LncRNA LINC00460 was previously reported to play a critical regulatory role in many ...

    Yali Xu, Zhixin Qiu, **wen Chen, Lihong Huang in Drug Delivery and Translational Research (2024)

  6. Article

    Open Access

    Understanding the genetic complexity of puberty timing across the allele frequency spectrum

    Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying 1,080 signals for age at menarche. Collectively, th...

    Katherine A. Kentistou, Lena R. Kaisinger, Stasa Stankovic, Marc Vaudel in Nature Genetics (2024)

  7. No Access

    Article

    β-hydroxybutyrate impairs nasopharyngeal carcinoma cell aggressiveness via histone deacetylase 4 inhibition

    Cancer stem cell phenotype confers tumor aggressiveness in multiple malignancies, including nasopharyngeal carcinoma (NPC). Many studies supported that β-hydroxybutyrate (BHB), a ketone body, acts as an epigen...

    **qiao Huang, **an Chen, Hong Lin, **ufen Chen in Molecular & Cellular Toxicology (2024)

  8. No Access

    Article

    A block-based adaptive high fidelity reversible data hiding scheme in interpolation domain

    Reversible Data Hiding (RDH) schemes enjoy the accomplishment of achieving high embedding capacity (EC) in interpolation domain. However, most existing methods usually embed the secret data into non-reference ...

    Zhiyun Huang, Yu Lin, **aofeng Chen in Multimedia Tools and Applications (2024)

  9. Article

    Open Access

    Roles of non-coding RNA in diabetic cardiomyopathy

    In recent years, the incidence of diabetes has been increasing rapidly, posing a serious threat to human health. Diabetic cardiomyopathy (DCM) is characterized by cardiomyocyte hypertrophy, myocardial fibrosis...

    ** Yao, **nyue Huang, Jianghua Chen, Weiqiang Lin in Cardiovascular Diabetology (2024)

  10. Article

    Open Access

    A broad neutralizing nanobody against SARS-CoV-2 engineered from an approved drug

    SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its receptor binding domain. Blocking this interaction has been proven to be an ...

    Qianyun Liu, Yuchi Lu, Chenguang Cai, Yanyan Huang, Li Zhou in Cell Death & Disease (2024)

  11. Article

    Open Access

    The importance of mother-child interaction on smart device usage and behavior outcomes among toddlers: a longitudinal study

    In recent years, smart devices have become an integral part of daily life. However, longitudinal studies, particularly those regarding the relationship between toddlers’ smart device usage and behavioral outco...

    Pairote Chakranon, Jian-Pei Huang in Child and Adolescent Psychiatry and Mental… (2024)

  12. Article

    Open Access

    Measurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector

    Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...

    G. Aad, E. Aakvaag, B. Abbott, S. Abdelhameed, K. Abeling in Journal of High Energy Physics (2024)

  13. Article

    Open Access

    Search for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV

    A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...

    A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic in Journal of High Energy Physics (2024)

  14. Article

    Open Access

    Structural basis for recruitment of peptidoglycan endopeptidase MepS by lipoprotein NlpI

    Peptidoglycan (PG) sacculi surround the cytoplasmic membrane, maintaining cell integrity by withstanding internal turgor pressure. During cell growth, PG endopeptidases cleave the crosslinks of the fully close...

    Shen Wang, Chun-Hsiang Huang, Te-Sheng Lin, Yi-Qi Yeh in Nature Communications (2024)

  15. Article

    Author Correction: Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice

    **n-huang Lv, **ao-xia Cong, **-liang Nan, **ng-mei Lu in Acta Pharmacologica Sinica (2024)

  16. Article

    Open Access

    C-H-activated Csp2-Csp3 diastereoselective gridization enables ultraviolet-emitting stereo-molecular nanohydrocarbons with mulitple H···H interactions

    Gridization is an emerging molecular integration technology that enables the creation of multifunctional organic semiconductors through precise linkages. While Friedel-Crafts gridization of fluorenols is poten...

    Ying Wei, Chunxiao Zhong, Yue Sun, Shuwei Ma, Mingjian Ni in Nature Communications (2024)

  17. No Access

    Article

    Benefit of consolidative radiation in patients with extranodal limited-stage diffuse large B-cell lymphoma: a multicenter retrospective study in China

    Approximately 40% of limited-stage (stage I and II) diffuse large B-cell lymphoma (LS-DLBCL) presents with extranodal disease. Extranodal LS-DLBCL may have significant biological differences and associated wit...

    Huawei Weng, Le Yu, Zegeng Chen, Huageng Huang, **nggui Chen in Annals of Hematology (2024)

  18. Article

    Open Access

    Analysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy

    Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...

    Hong Chen, Ji-Hong Zhang, Qin Hao in International Journal of Colorectal Disease (2024)

  19. Article

    Open Access

    Locally advanced breast cancer patients should be cautious about the immediate breast reconstruction after mastectomy: a pooling analysis of safety and efficacy

    The purpose of this study was to compare safety and efficacy outcomes between immediate breast reconstruction (IBR) and mastectomy alone in locally advanced breast cancer patients.

    Cheng-Yu Zeng, Yan-Yu Qiu, Jia-Yi Li, Jian-Hao Huang in World Journal of Surgical Oncology (2024)

  20. No Access

    Article

    Fasn involved in the nephrotoxicity induced by polystyrene nanoplastics and the intervention of melatonin through intestinal microbiota-mediated lipid metabolism disorder

    Nanoplastics (NPs) can accumulate in the kidney and cause kidney injury, but the multi-organ interaction mechanism and preventive measures of kidney injury are still unclear. In this study, in vivo (60 µg/day, 42...

    Huiwen Kang, Danyang Huang, Jiaru **g, Wei Zhang, Lei Zhang, **gyu Wang in Nano Research (2024)

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