2,924 Result(s)
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**n-Lei Li
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Article
Synthesis of Chlorfenazole from 2-Chlorobenzalmalononitrile Extracted from Expired Tear-Gas Grenade
Tear gases were originally manufactured as weapons that could severely disable or kill enemy troops. Though banned in war, these chemicals are still used in domestic policing. Due to ammunition management rule...
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Seismic events extraction method based on the B-COSFIRE filter combined with the differential evolution algorithm
Based on an analysis of the information processing mechanism in the primary visual cortex of biological vision, this study proposes an integration method of bar-combination of shifted filter responses (B-COSFI...
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Evaluation of fragility fracture risk using deep learning based on ultrasound radio frequency signal
It was essential to identify individuals at high risk of fragility fracture and prevented them due to the significant morbidity, mortality, and economic burden associated with fragility fracture. The quantitat...
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Open AccessUnlocking the function promiscuity of old yellow enzyme to catalyze asymmetric Morita-Baylis-Hillman reaction
Exploring the promiscuity of native enzymes presents a promising strategy for expanding their synthetic applications, particularly for catalyzing challenging reactions in non-native contexts. In this study, we...
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Open AccessModulation of dlPFC function and decision-making capacity by repetitive transcranial magnetic stimulation in methamphetamine use disorder
This study explores the impact of repetitive transcranial magnetic stimulation (rTMS) on decision-making capabilities in individuals with methamphetamine use disorder (MUD), alongside potential underlying psyc...
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Open AccessObservation of stacking engineered magnetic phase transitions within moiré supercells of twisted van der Waals magnets
Recent demonstrations of moiré magnetism, featuring exotic phases with noncollinear spin order in the twisted van der Waals (vdW) magnet chromium triiodide CrI3, have highlighted the potential of twist engineerin...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Open AccessMetatranscriptomics-guided genome-scale metabolic reconstruction reveals the carbon flux and trophic interaction in methanogenic communities
Despite rapid advances in genomic-resolved metagenomics and remarkable explosion of metagenome-assembled genomes (MAGs), the function of uncultivated anaerobic lineages and their interactions in carbon mineral...
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Pannonibacter tanglangensis sp. nov., a New Species Isolated from Pond Sediment
Two bacterial strains (XCT-34T and XCT-53) isolated from sediment samples of an artificial freshwater reservoir were analyzed using a polyphasic approach. The two isolates are aerobic, Gram-stain-negative, oxidas...
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Open AccessEstablishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its late diagnosis, high therapeutic resistance, and a dearth of ...
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Open AccessArtificial sweeteners and risk of incident cardiovascular disease and mortality: evidence from UK Biobank
Artificial sweeteners are widely popular worldwide as substitutes for sugar or caloric sweeteners, but there are still several important unknowns and controversies regarding their associations with cardiovascu...
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Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical features, including symptoms of pruritus and pain, scaly lesions, and histologically, acantho...
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Local environmental legislation and employment growth: evidence from Chinese manufacturing firms
In China, there exists a huge debate for a long time on whether a double dividend, reducing pollution emissions and boosting employment, can be achieved by intensifying environmental regulations. In this paper...
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Article
Sorafenib sensitization in tumor therapy by iron overload and AMPK activation
Sorafenib, as a first-line drug for advanced hepatocellular carcinoma (HCC), could trigger ferroptosis by inhibiting cystine/glutamate transporter. However, low-level intracellular iron and insufficient activa...
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Epidermal visualized health monitoring system based on stretchable and washable TPU hybrid conductive microtextiles
Electronic textiles, an emerging class of electronic technology, offer exciting opportunities for seamless integration with the human body. Numerous applications have been developed based on electronic textile...
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Open AccessC-H-activated Csp2-Csp3 diastereoselective gridization enables ultraviolet-emitting stereo-molecular nanohydrocarbons with mulitple H···H interactions
Gridization is an emerging molecular integration technology that enables the creation of multifunctional organic semiconductors through precise linkages. While Friedel-Crafts gridization of fluorenols is poten...
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Open AccessA nomogram combining CT-based radiomic features with clinical features for the differentiation of benign and malignant cystic pulmonary nodules
Currently, the differentiation between benign and malignant cystic pulmonary nodules poses a significant challenge for clinicians. The objective of this retrospective study was to construct a predictive model ...
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Characterization of Gut Microbiota in Rats and Rhesus Monkeys After Methamphetamine Self-administration
Methamphetamine (MA) is one of the most abused drugs globally, but the mechanism of its addiction remains unclear. Several animal studies have shown that the gut microbiota (GM) influences addictive behaviors,...
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Open AccessDevelopment of a Pt(II) compound based on indocyanine green@human serum albumin nanoparticles: integrating phototherapy, chemotherapy and immunotherapy to overcome tumor cisplatin resistance
Cisplatin resistance is the main cause for the failure of cancer therapy. To solve the problem, we proposed to develop a novel human serum albumin (HSA) nanoplatform to integrate chemotherapy, photothermal the...
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Open AccessMicrofluidics-enabled mesenchymal stem cell derived Neuron like cell membrane coated nanoparticles inhibit inflammation and apoptosis for Parkinson’s Disease
Parkinson’s disease (PD) is the second largest group of neurodegenerative diseases, and its existing drug treatments are not satisfactory. Natural cell membrane drugs are used for homologous targeting to enhan...
