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Lymphoma cell culture under serum-free conditions
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Chapter
Purification and Culture of Erythroid Progenitor Cells
Purified cells can be utilized for studies involving growth factor regulated development of erythroid progenitor cells. For example, Fig. 4 demonstrates the expression pattern of β-globin and glyceraldehyde ph...
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Article
p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity
It has been shown that oncoprotein p28GANK, which is consistently overexpressed in human hepatocellular carcinoma (HCC), plays a critical role in tumorigenesis of HCC. However, the underlying mechanism remains un...
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Protocol
Coupling of Dephosphorylation and Nuclear Export of Smads in TGF-β Signaling
In eukaryotes, regulation of signaling mediators/effectors in the nucleus is one of the principal mechanisms that govern duration and strength of signaling. Smads are a family of structurally related intracell...
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Article
M. tuberculosis H37Rv Infection of Chinese Rhesus Macaques
Mycobacterium tuberculosis is the most common communicable infectious disease worldwide and the top killer of human immunodeficiency virus (HIV)-infected people. Because of common dual HI...
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Article
Clinical Study of Autologous Cytokine-Induced Killer Cells for the Treatment of Elderly Patients with Diffuse Large B-Cell Lymphoma
To evaluate the effectiveness and safety of autologous cytokine-induced killer (CIK) cells in elderly patients with diffuse large B-cell lymphoma. Peripheral blood mononuclear cells (PBMC) were isolated from n...
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Article
Open AccessPachytene piRNAs instruct massive mRNA elimination during late spermiogenesis
Spermatogenesis in mammals is characterized by two waves of piRNA expression: one corresponds to classic piRNAs responsible for silencing retrotransponsons and the second wave is predominantly derived from non...
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Article
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis
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Article
Vimentin Regulates Neuroplasticity in Transected Spinal Cord Rats Associated with micRNA138
Spinal cord injury (SCI) often results in motor disability concomitant with limit neuroplasticity; the underlying mechanism, however, is still unclear. This study established spinal cord transection rats model...
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Article
Endoplasmic Reticulum Protein 29 Protects Axotomized Neurons from Apoptosis and Promotes Neuronal Regeneration Associated with Erk Signal
Spinal cord injury (SCI) results in a series of severe dysfunction of sensory and motor functions, while the molecular mechanisms that cause these dysfunctions remain elusive. Using proteomics technology, West...
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Article
YAP activates the Hippo pathway in a negative feedback loop
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Article
Open AccessRelB/NF-κB links cell cycle transition and apoptosis to endometrioid adenocarcinoma tumorigenesis
Dysfunction of nuclear factor-κB (NF-κB) signaling has been causally associated with numerous human malignancies. Although the NF-κB family of genes has been implicated in endometrial carcinogenesis, information ...
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Article
Erratum: YAP activates the Hippo pathway in a negative feedback loop
Correction to: Cell Research (2015) 25:1175–1178. doi:10.1038/cr.2015.101; published online 28 August 2015 The authors apologized for the mistake of mis-labeling the affiliation for Drs **aoming Dai, Huan Liu,...
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Article
Open AccessImmunosuppressive effect of arsenic trioxide on islet xenotransplantation prolongs xenograft survival in mice
The role of arsenic trioxide (As2O3) in inhibiting immune rejection and prolonging islet allograft survival has been identified in islet allotransplantation. This study aims to explore the role of As2O3 in islet ...
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Article
Open AccessNovel interactions between ERα-36 and STAT3 mediate breast cancer cell migration
Breast cancer is the leading cause of cancer death in women worldwide which is closely related to metastasis. But the exact molecular mechanism of ERα-36 and STAT3 on metastasis is still not fully understood.
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Article
A Dual Role of ATM in Ischemic Preconditioning and Ischemic Injury
The ataxia-telangiectasia mutated (ATM) protein is regarded as the linchpin of cellular defenses to stress. Deletion of ATM results in strong oxidative stress and degenerative diseases in the nervous system. H...
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Article
Open Access863 genomes reveal the origin and domestication of chicken
Despite the substantial role that chickens have played in human societies across the world, both the geographic and temporal origins of their domestication remain controversial. To address this issue, we analy...
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Article
Open AccessClinical value and potential mechanisms of COL8A1 upregulation in breast cancer: a comprehensive analysis
The situation faced by breast cancer patients, especially those with triple-negative breast cancer, is still grave. More effective therapeutic targets are needed to optimize the clinical management of breast c...
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Article
Author Correction: 863 genomes reveal the origin and domestication of chicken
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessFibroblasts in cancer dormancy: foe or friend?
Cancer dormancy is defined that the residual cancer cells could enter into a state of quiescence and patients remain asymptomatic for years or even decades after anti-tumor therapies. Fibroblasts, which repres...