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Article
Bone age assessment based on different MRI modalities of the proximal humerus epiphysis: the comparisons of T1WI, T2WI, and PDWI
Bone age assessment (BAA) is crucial in various fields, including legal proceedings, athletic competitions, and clinical medicine. However, the use of X-ray methods for age estimation without medical indicatio...
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Article
Clinical treatment of cryptococcal meningitis: an evidence-based review on the emerging clinical data
Cryptococcal meningitis (CM) is a fatal fungal central nervous system (CNS) infection caused by Cryptococcus infecting the meninges and/or brain parenchyma, with fever, headache, neck stiffness, and visual distur...
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Article
Inflammation-related molecular signatures involved in the anticancer activities of brigatinib as well as the prognosis of EML4-ALK lung adenocarcinoma patient
Although ALK tyrosine kinase inhibitors (ALK-TKIs) have shown remarkable benefits in EML4-ALK positive NSCLC patients compared to conventional chemotherapy, the optimal sequence of ALK-TKIs treatment remains u...
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Article
Design and prototy** of the readout electronics for the transition radiation detector in the high energy cosmic radiation detection facility
The high energy cosmic-radiation detection (HERD) facility is planned to launch in 2027 and scheduled to be installed on the China Space Station. It serves as a dark matter particle detector, a cosmic ray inst...
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Article
m6A demethylation of FOSL1 mRNA protects hepatoma cells against necrosis under glucose deprivation
Stress-adaptive mechanisms enabling cancer cells to survive under glucose deprivation remain elusive. N6-methyladenosine (m6A) modification plays important roles in determining cancer cell fate and cellular stres...
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Article
Open AccessAssociations between sleep quality and co** style among front-line nurses: a cross-sectional study in China
Good sleep is crucial for healthcare professionals, especially nurses, to prevent errors and injuries that may occur during caregiving. This study investigated the sleep quality and co** styles of nurses dur...
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Article
Integrated multiomic profiling of breast cancer in the Chinese population reveals patient stratification and therapeutic vulnerabilities
Molecular profiling guides precision treatment of breast cancer; however, Asian patients are underrepresented in publicly available large-scale studies. We established a comprehensive multiomics cohort of 773 ...
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Article
Open AccessThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...
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Article
Beam dynamics study of the photoinjector at Wuhan advanced light source
A full-energy LINAC is under development at Wuhan Advanced Light Source (WALS) to provide beams for the 1.5 GeV storage ring proposed as a fourth-generation synchrotron radiation light source and a future free...
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Article
Topological Confinement in Reversibly Interlocked Polymer Networks
Recently, we reported a series of reversibly interlocked polymer networks (RILNs), whose mechanical robustness and functionalities improvement was believed to be derived from topological interlocking of two su...
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Article
Functional-structural decoupling in visual network is associated with cognitive decline in patients with type 2 diabetes mellitus: evidence from a multimodal MRI analysis
Type 2 diabetes mellitus (T2DM) and cognitive dysfunction are highly prevalent disorders worldwide. Although visual network (VN) alteration and functional-structural coupling are potential warning factors for ...
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Article
Open AccessThe correlation between lung ultrasound scores and outcomes of high-flow nasal cannula therapy in infants with severe pneumonia
The study aimed to explore the effectiveness of bedside lung ultrasound (LUS) combined with the PaO2/FiO2 (P/F) ratio in evaluating the outcomes of high-flow nasal cannula (HFNC) therapy in infants with severe pn...
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Article
Open AccessExperience of copy number variation sequencing applied in spontaneous abortion
We evaluated the value of copy number variation sequencing (CNV-seq) and quantitative fluorescence (QF)-PCR for analyzing chromosomal abnormalities (CA) in spontaneous abortion specimens.
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Chapter and Conference Paper
Research on Adaptability of Downhole Two-Stage Series Hydrocyclone Separation Technology
In view of the disadvantages of the separation technology in the same well injection -production technology, the downhole two-stage series hydrocyclone separation technology is put forward in order to overcome...
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Article
Open AccessAdvances in nuclear detection and readout techniques
“A Craftsman Must Sharpen His Tools to Do His Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear physics, and particle astrophysics to reveal the nat...
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Article
Open AccessMaternal dominance contributes to subgenome differentiation in allopolyploid fishes
Teleost fishes, which are the largest and most diverse group of living vertebrates, have a rich history of ancient and recent polyploidy. Previous studies of allotetraploid common carp and goldfish (cyprinids)...
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Article
Intestinal Symptoms Among Children aged 2–7 Years with Autism Spectrum Disorder in 13 Cities of China
Background: Autism spectrum disorder (ASD) is a multifactorial, pervasive, neurodevelopmental disorder, of which intestinal symptoms collectively represent one of the most common comorbidities. Methods: In this s...
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Article
Open AccessID1 expressing macrophages support cancer cell stemness and limit CD8+ T cell infiltration in colorectal cancer
Elimination of cancer stem cells (CSCs) and reinvigoration of antitumor immunity remain unmet challenges for cancer therapy. Tumor-associated macrophages (TAMs) constitute the prominant population of immune ce...
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Article
Open AccessGenetic and cultural adaptations underlie the establishment of dairy pastoralism in the Tibetan Plateau
Domestication and introduction of dairy animals facilitated the permanent human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan Plateau remains poorly understood. Little ...
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Article
Open AccessField-free spin-orbit switching of perpendicular magnetization enabled by dislocation-induced in-plane symmetry breaking
Current induced spin-orbit torque (SOT) holds great promise for next generation magnetic-memory technology. Field-free SOT switching of perpendicular magnetization requires the breaking of in-plane symmetry, w...
