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11,047 Result(s)
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Article
Temperate Stutzerimonas Phage Encoding Toxin-Antitoxin System Genes Represents a Novel Genus
Stutzerimonas have been extensively studied due to their remarkable metabolic and physiological diversity. However, research on its phages is currently limited. In this study, we isolated a novel double-stranded ...
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Morphogenesis and Molecular Phylogeny of a Marine Urostylid Ciliate Apokeronopsis wrighti (Protista, Ciliophora, Hypotrichia)
Hypotrichs are one of the highly differentiated ciliated lineages which play important roles in ecological, environmental, evolutionary and basic biological studies. In the present study, we investigated the l...
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Risk Factors for Preoperative Cerebral Infarction in Infants with Moyamoya Disease
There have been few reports on the risk factors for preoperative cerebral infarction in childhood moyamoya disease (MMD) in infants under 4 years. The aim of this retrospective study is to identify clinical an...
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Open AccessCultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
The Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the number of Atribacterota genome sequences retrieved from environmental samples ...
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Open AccessMechanistic and therapeutic perspectives of non-coding RNA-modulated apoptotic signaling in diabetic retinopathy
Diabetic retinopathy (DR), a significant and vision-endangering complication associated with diabetes mellitus, constitutes a substantial portion of acquired instances of preventable blindness. The progression...
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Article
Open AccessOpen-hole extension limit of offshore extended-reach well considering formation collapse
The current extension limit prediction model for offshore extended-reach well (ERW) in mudstone does not consider the formation collapse, which poses a huge risk to offshore drilling construction. To address t...
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Open AccessDo global innovation networks influence the status of global value chains? Based on a patent cooperation network perspective
Under the impact of economic globalization, the internationalization of production and trade has given rise to global value chains (GVCs) and global innovation networks (GINs); however, few studies have explor...
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Open AccessIntrauterine fetal death due to rupture of umbilical vessels: a rare case of furcate cord insertion
Furcate cord insertion refers to the separation of umbilical vessels before reaching the placenta, where the branching vessels normally attach at the edge of the placental parenchyma or near the placental memb...
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Open AccessDifferent antithrombotic strategies after coronary artery bypass grafting to prevent adverse events: a retrospective analysis
Coronary artery bypass grafting (CABG) is associated with antithrombotic therapy in terms of postoperative adverse events; however, it is still unknown whether the early use of such drugs after CABG is safe an...
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Article
Sample Size Determination and Study Design Impact on Dose-Scale Pharmacodynamic Bioequivalence: a Case Study Using Orlistat
Dose-scale pharmacodynamic bioequivalence is recommended for evaluating the consistency of generic and innovator formulations of certain locally acting drugs, such as orlistat. This study aimed to investigate ...
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Open AccessGinsenoside Rb1 reduces oxidative/carbonyl stress damage and dysfunction of RyR2 in the heart of streptozotocin-induced diabetic rats
Oxidative stress may contribute to cardiac ryanodine receptor (RyR2) dysfunction in diabetic cardiomyopathy. Ginsenoside Rb1 (Rb1) is a major pharmacologically active component of ginseng to treat cardiovascul...
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Article
Open AccessBibliometric and visual analysis in the field of two-dimensions nano black phosphorus in cancer from 2015 to 2023
This study aims to provide a comprehensive summary of the status and trends of Two-Dimensional Nano Black Phosphorus (2D nano BP) in cancer research from 2015 to 2023, offering insights for future studies. To ...
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Article
Open AccessIn a rat model of bypass DuraGraft ameliorates endothelial dysfunction of arterial grafts
Coronary artery bypass surgery can result in endothelial dysfunction due to ischemia/reperfusion (IR) injury. Previous studies have demonstrated that DuraGraft helps maintain endothelial integrity of saphenous...
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Similar tolerance of urban birds towards both benign human and lethal cat predators
Prey animals make crucial escape decisions when confronted by predators. Previous research, predominantly employing human surrogates, has consistently shown that urban-dwelling prey exhibit greater tolerance f...
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Article
Open AccessA novel variant in GAS2 is associated with autosomal dominant nonsyndromic hearing impairment in a Chinese family
Knockout of GAS2 (growth arrest-specific protein 2), causes disorganization and destabilization of microtubule bundles in supporting cells of the cochlear duct, leading to hearing loss in vivo. However, the molec...
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Article
Open AccessFacile synthesis of elastin nanogels encapsulated decursin for castrated resistance prostate cancer therapy
Nanogels offer hope for precise drug delivery, while addressing drug delivery hurdles is vital for effective prostate cancer (PCa) management. We developed an injectable elastin nanogels (ENG) for efficient dr...
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Article
Correction: Human Bone Marrow Mesenchymal Stem Cell–Derived Exosomes Attenuate Blood–Spinal Cord Barrier Disruption via the TIMP2/MMP Pathway After Acute Spinal Cord Injury
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Article
Development of optimized functional clove fortified probiotic yoghurt
We focused on assessing the antimicrobial effects of functional yoghurts supplemented with clove and probiotics. The formulation of aqueous clove extract (ACE) incorporated with probiotic yoghurt (Streptococcus t...
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Article
The safety of benzodiazepines and related drugs during pregnancy: an updated meta-analysis of cohort studies
The prevalence of benzodiazepines and related drugs (BZRDs) use during pregnancy increased sharply in recent years. Thus, there are concerns regarding the pregnancy outcomes following exposure to BZRDs.
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Correction to: Waterlogging resistance and evaluation of physiological mechanism of three peach (Prunus persica) rootstocks