4 Result(s)

Article

Recombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β

Hua-Li Wan, Bing-Ge Zhang, Chongyang Chen… in Signal Transduction and Targeted Therapy (2022)

Article

STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17

In tauopathies, memory impairment positively strongly correlates with the amount of abnormal tau aggregates; however, how tau accumulation induces synapse impairment is unclear. Recently, we found that human t...

**ao-Yue Hong, Hua-Li Wan, Ting Li… in Signal Transduction and Targeted Therapy (2020)

Article

Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice

In vertebrates, the type 1 parathyroid hormone receptor (PTH1R) is a critical regulator of skeletal development and homeostasis; however, how it is modulated is incompletely understood. Here we report that del...

Xuekun Fu, Bo Zhou, Qinnan Yan, Chu Tao… in Signal Transduction and Targeted Therapy (2020)

Article

Validation and clinicopathologic associations of a urine-based bladder cancer biomarker signature

To validate the expression of a urine-based bladder cancer associated diagnostic signature comprised of 10 targets; ANG, CA9, MMP9, MMP10, SERPINA1, APOE, SDC1, VEGFA, SERPINE1 and IL8 in bladder tumor tissues.

Ge Zhang, Evan Gomes-Giacoia, Yunfeng Dai, Adrienne Lawton… in Diagnostic Pathology (2014)