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Article
Phosphodiesterase 8 (PDE8): Distribution and Cellular Expression and Association with Alzheimer’s Disease
Phosphodiesterase 8 (PDE8), as a member of PDE superfamily, specifically promotes the hydrolysis and degradation of intracellular cyclic adenosine monophosphate (cAMP), which may be associated with pathogenesi...
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Article
Activation of 5-HT6 Receptors in the Ventrolateral Orbital Cortex Produces Anti-Anxiodepressive Effects in a Rat Model of Neuropathic Pain
The comorbidity of anxiety and depression frequently occurs in patients with neuropathic pain. The ventrolateral orbital cortex (VLO) plays a critical role in mediating neuropathic pain and anxiodepression in ...
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Article
Efficient piezo-catalytic dye degradation using piezoelectric 6H-SiC under harsh conditions
The development of novel piezoelectric catalysts against harsh conditions is indeed crucial for improving the piezo-catalytic degradation efficiency of colored organic dyes in wastewater. In this work, 6H-SiC ...
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Article
Porous high-entropy rare-earth phosphate (REPO4, RE = La, Sm, Eu, Ce, Pr and Gd) ceramics with excellent thermal insulation performance via pore structure tailoring
Thermal insulation materials play an increasingly important role in protecting mechanical parts functioning at high temperatures. In this study, a new porous high-entropy (La1/6Ce1/6Pr1/6Sm1/6Eu1/6Gd1/6)PO4 (HE (...
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Article
Nitric Oxide Promotes Adventitious Rooting in Cucumber Under Drought Stress Through Regulating Ascorbate Glutathione Cycle and Protein S-Nitrosylation
Drought stress can impair plant growth and development. Nitric oxide (NO), a gas signaling molecule, delays injuries caused by abiotic stress. This study explored the roles of NO during adventitious rooting in...
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Article
Open AccessInvestigation of high-dose radiotherapy's effect on brain structure aggravated cognitive impairment and deteriorated patient psychological status in brain tumor treatment
This study aims to investigate the potential impact of high-dose radiotherapy (RT) on brain structure, cognitive impairment, and the psychological status of patients undergoing brain tumor treatment. We recrui...
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Article
CsSHMT3 gene enhances the growth and development in cucumber seedlings under salt stress
Salt stress is one of the major factors limiting plant growth and productivity. Many studies have shown that serine hydroxymethyltransferase (SHMT) gene play an important role in growth, development and stress re...
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Open AccessButyrate and iso-butyrate: a new perspective on nutrition prevention of gestational diabetes mellitus
Dietary imbalance, such as a lower proportion of complex carbohydrates and a higher protein diet, may contribute to gestational diabetes mellitus (GDM) risks through their metabolisms. However, there is a lack...
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Article
Open AccessA tomato NAC transcription factor, SlNAP1, directly regulates gibberellin-dependent fruit ripening
In tomato (Solanum lycopersicum), the ripening of fruit is regulated by the selective expression of ripening-related genes, and this procedure is controlled by transcription factors (TFs). In the various plant-sp...
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Retraction Note: Converging concepts of sustainability and supply chain networks: a systematic literature review approach
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Article
Initial Upper Palaeolithic material culture by 45,000 years ago at Shiyu in northern China
The geographic expansion of Homo sapiens populations into southeastern Europe occurred by ∼47,000 years ago (∼47 ka), marked by Initial Upper Palaeolithic (IUP) technology. H. sapiens was present in western Siber...
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Article
Competitive oxidation behavior of Ni-based superalloy GH4738 at extreme temperature
A high thrust-to-weight ratio poses challenges to the high-temperature performance of Ni-based superalloys. The oxidation behavior of GH4738 at extreme temperatures has been investigated by isothermal and non-...
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Article
Status investigation and analysis of oyster aquaculture industry in China: evidence from Zhanjiang
Oyster is an important fishing resource that is produced in coastal areas around the world. Over the past few decades, China’s oyster aquaculture has flourished and is the world’s largest in terms of productio...
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Open AccessEnhanced grading methods for lumbar paraspinal fat infiltration and its prognostic value in predicting lumbar disc herniation
The simplified 3-grade system for measuring fat infiltration in the paraspinal muscles is widely utilized. In comparing our proposed 4-grade system to the existing 3-grade system, we evaluated its impact on re...
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Comments on the Oyster Aquaculture Industry in China: 1985–2020
Since the 1980s, China’s oyster aquaculture has grown quickly in the past four decades, and it became the top mariculture species in China with an annual production of 5.23 million in 2019. Understanding the g...
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Open AccessAncient mitogenomes reveal a high maternal genetic diversity of Pleistocene woolly rhinoceros in Northern China
Woolly rhinoceros (Coelodonta antiquitatis) is a typical indicator of cold-stage climate that was widely distributed in Northern Hemisphere during the Middle-Late Pleistocene. Although a plethora of fossils have ...
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Design of novel Ni-based superalloys with better oxidation resistance with the aid of machine learning
Oxidation resistance is a critical criterion to evaluate the service life of Ni-based superalloys. In this work, the quantitative relationship between various factors including temperature, time and alloying e...
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Article
Open AccessStructural map** of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling
PEAK pseudokinases regulate cell migration, invasion and proliferation by recruiting key signaling proteins to the cytoskeleton. Despite lacking catalytic activity, alteration in their expression level is asso...
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Article
Ezrin accelerates breast cancer liver metastasis through promoting furin-like convertase-mediated cleavage of Notch1
Ezrin, known as a crosslinker between the plasma membrane and actin cytoskeleton, is closely associated with breast cancer (BC) progression. Here, we explored a novel role of ezrin in breast cancer liver metas...
