251 Result(s)
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Impact of the COVID-19 infection on children with allergic diseases in China
The COVID-19 pandemic has prompted investigations into the association between this novel virus and allergic diseases, particularly asthma in children. However, the nature of this relationship remains poorly e...
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Open AccessImpact assessment of self-medication on COVID-19 prevalence in Gauteng, South Africa, using an age-structured disease transmission modelling framework
To assess the impact of self-medication on the transmission dynamics of COVID-19 across different age groups, examine the interplay of vaccination and self-medication in disease spread, and identify the age gr...
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FOXP3 expression in esophageal squamous cell carcinoma
Investigating the impact of FOXP3 (transcription factor forkhead box P3) expression on the biological behavior of esophageal squamous cell carcinoma (ESCC) and its influence on the sensitivity of ESCC cells to...
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Open AccessAssociation between high-altitude polycythemia and hypertension: a cross-sectional study in adults at Tibetan ultrahigh altitudes
The study aimed to evaluate the association between high-altitude polycythemia and hypertension in adults residing on Anduo County’s plateau, which is located 4700 meters above sea level. A total of 387 indivi...
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Open AccessWTAP-mediated m6A modification of lncRNA Snhg1 improves myocardial ischemia-reperfusion injury via miR-361-5p/OPA1-dependent mitochondrial fusion
Myocardial ischemia-reperfusion injury (MIRI) is caused by reperfusion after ischemic heart disease. LncRNA Snhg1 regulates the progression of various diseases. N6-methyladenosine (m6A) is the frequent RNA modifi...
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Open AccessDiagnosis and treatment of the Ehlers-Danlos syndromes in China: synopsis of the first guidelines
The Ehlers-Danlos syndromes (EDS) are a group of rare hereditary connective tissue disorders. EDS is clinically and genetically heterogeneous and usually involves multiple systems. There are 14 subtypes of EDS...
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Open AccessNeuroprotective effects of apigenin on retinal ganglion cells in ischemia/reperfusion: modulating mitochondrial dynamics in in vivo and in vitro models
Retinal ischemia/reperfusion (RIR) is implicated in various forms of optic neuropathies, yet effective treatments are lacking. RIR leads to the death of retinal ganglion cells (RGCs) and subsequent vision loss...
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Open AccessTwo surgical strategies (early carotid reperfusion vs. Central aortic repair-first) of acute type a aortic dissection complicated with cerebral malperfusion syndrome: a meta-analysis and systematic review
Cerebral malperfusion (CM) is a common comorbidity in acute type A aortic dissection (ATAAD), which is associated with high mortality and poor neurological prognosis. This meta-analysis investigated the surgic...
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Open AccessThe radiological characteristics, tertiary lymphoid structures, and survival status associated with EGFR mutation in patients with subsolid nodules like stage I-II LUAD.
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) recommended for the patients with subsolid nodule in early lung cancer stage is not routinely. The clinical value and impact in patients ...
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Open AccessSingle-cell RNA sequencing reveals recruitment of the M2-like CCL8high macrophages in Lewis lung carcinoma-bearing mice following hypofractionated radiotherapy
Tumor-associated macrophages (TAMs) play a pivotal role in resha** the tumor microenvironment following radiotherapy. The mechanisms underlying this reprogramming process remain to be elucidated.
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Open AccessThe health-care utilization and economic burden in patients with genetic skeletal disorders
Most genetic skeletal disorders (GSD) were complex, disabling and life-threatening without effective diagnostic and treatment methods. However, its impacts on health system have not been well studied. The stud...
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Open AccessEffect of no eyeglasses sales on the quality of eye care: an experimental evidence from China
Eye examinations and eyeglasses acquisition are typically integrated into a cohesive procedure in China. We conducted a randomized controlled trial using incognito standardized patient (SP) approach to evaluat...
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Associations between long-term averages of metabolic parameters in adulthood and cardiac structure and function in later life
The effects of long-term levels of body mass index (BMI), blood pressure (BP), plasma lipids and fasting blood glucose (FBG) on the cardiac structure and function in later life in general population are to eva...
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Open AccessPredictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway
Breast cancer (BC) is a multifaceted disease characterized by distinct molecular subtypes and varying responses to treatment. In BC, the phosphatidylinositol 3-kinase (PI3K) pathway has emerged as a crucial co...
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Open AccessWhat are people’s attitudes toward medical insurance fraud whistleblowers? a study from China
Medical insurance fraud has caused huge losses to countries around the world, and public reporting has become an important means to combat medical insurance fraud. The attitude of medical insurance fraud whist...
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Open AccessWhat influences the public’s willingness to report health insurance fraud in familiar or unfamiliar healthcare settings? a cross-sectional study of the young and middle-aged people in China
Young and middle-aged people are important participants in the fight against health insurance fraud. The study aims to investigate the differences in their willingness to report health insurance fraud and the ...
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Integrated Chinese and Western Medicine in Treatment of Bronchopleural Fistula with Mycobacterium abscessus: A Case Report
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COVID-19 in Systemic Lupus Erythematosus patients treated with belimumab: a retrospective clinical study
Routine use of immunosuppressive agents in systemic lupus erythematosus (SLE) patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) potentially increases the risk of adverse outco...
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Open AccessIdentification of candidate DNA methylation biomarkers related to Alzheimer’s disease risk by integrating genome and blood methylome data
Alzheimer disease (AD) is a common neurodegenerative disease with a late onset. It is critical to identify novel blood-based DNA methylation biomarkers to better understand the extent of the molecular pathways...
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Open AccessThe expanding Pandora’s toolbox of CD8+T cell: from transcriptional control to metabolic firing
CD8+ T cells are the executor in adaptive immune response, especially in anti-tumor immunity. They are the subset immune cells that are of high plasticity and multifunction. Their development, differentiation, ac...
