81 Result(s)

Article

Astaxanthin-mediated Nrf2 activation ameliorates glucocorticoid-induced oxidative stress and mitochondrial dysfunction and impaired bone formation of glucocorticoid-induced osteonecrosis of the femoral head in rats

Osteonecrosis of the femoral head caused by glucocorticoids (GIONFH) is a significant issue resulting from prolonged or excessive clinical glucocorticoid use. Astaxanthin, an orange-red carotenoid present in m...

Weidan Wang, Hongyi Jiang, Jiachen Yu… in Journal of Orthopaedic Surgery and Research (2024)

Article

Evaluation of TikTok videos on acute pancreatitis: content quality and reliability analysis

Acute pancreatitis (AP) is a common acute digestive system disorder, with patients often turning to TikTok for AP-related information. However, the platform’s video quality on AP has not been thoroughly invest...

Tianyang Mao, **n Zhao, Kangyi Jiang, Jie Yang, Qingyun **e… in BMC Public Health (2024)

Article

Immunosuppressive microvesicles-mimetic derived from tolerant dendritic cells to target T-lymphocytes for inflammation diseases therapy

The utilization of extracellular vesicles (EV) in immunotherapy, aiming at suppressing peripheral immune cells responsible for inflammation, has demonstrated significant efficacy in treating various inflammato...

Minghao Lin, Siyun Lei, Yingqian Chai, Jianghua Xu… in Journal of Nanobiotechnology (2024)

Article

Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-κB pathways via miR-29a-3p

As a natural extraction, astaxanthin is gaining increasing attention because of its safety and anti-tumor properties. It has been reported to participate in the progression of various types of cancer such as g...

Yajia Xu, Chengyi Jiang in Genes and Environment (2024)

Article

Microneedles loaded with cerium-manganese oxide nanoparticles for targeting macrophages in the treatment of rheumatoid arthritis

Rheumatoid arthritis (RA) is a prevalent inflammatory autoimmune disease characterised by persistent inflammation and joint damage with elevated levels of reactive oxygen species (ROS). Current treatment modal...

Tian **a, Yuting Zhu, Kaiqiang Li, Ke Hao, Yingqian Chai… in Journal of Nanobiotechnology (2024)

Article

Exploring the use of graphene lubricant and TiO₂ nanolubricants in micro deep drawing of stainless steel SUS301

This study investigates the effects of different lubrication conditions on drawing force and microcup formation during micro deep drawing (MDD). Results show that graphene lubricant, in combination with TiO₂ nano...

Di Pan, Guangqing Zhang, Fanghui Jia, Hui Wu… in The International Journal of Advanced Manu… (2024)

Article

Research on knowledge graph-driven equipment fault diagnosis method for intelligent manufacturing

In the process of rotating machinery fault diagnosis (RMFD), the lack of feature conditions leads to the problem of low accuracy of traditional rule-based reasoning methods FD. This paper proposed a knowledge ...

Chang Cai, Zhengyi Jiang, Hui Wu… in The International Journal of Advanced Manu… (2024)

Article

Effect of emerging digital technologies and methodologies combined with incentives on HbA1c in patients with type 2 diabetes mellitus: study protocol for a parallel, open randomized controlled trial

Type 2 diabetes mellitus (T2DM) is a common metabolic disease that requires long-term management and treatment. Digital intervention, as an emerging medical model, has been widely used in the treatment of T2DM...

Shao Zhong, **gyi Jiang, Hongying Liu, Ying Pan in Trials (2024)

Article

Preliminary exploration of hepatic parenchymal near-infrared fluorescence imaging technique via retrograde biliary approach: a feasibility study (with video)

This paper explores the feasibility and principle of hepatic parenteral fluorescence imaging technology after retrograde injection of indocyanine green (ICG) through endoscopic nasobiliary drainage (ENBD). The...

Fengwei Gao, Qingyun **e, **n Zhao, Manyu Yang, Kangyi Jiang… in Scientific Reports (2024)

Article

Acute ischemic stroke prediction and predictive factors analysis using hematological indicators in elderly hypertensives post-transient ischemic attack

Elderly hypertensive patients diagnosed with transient ischemic attack (TIA) are at a heightened risk for develo** acute ischemic stroke (AIS). This underscores the critical need for effective risk predictio...

Chang Shu, Chenguang Zheng, Da Luo, Jie Song, Zhengyi Jiang, Le Ge in Scientific Reports (2024)

Article

Radiological classification of the Heidelberg triangle and its application in laparoscopic pancreaticoduodenectomy for malignancies

The TRIANGLE operation benefits patients with pancreatic cancer; however, the Heidelberg triangle, where the operation occurs, contains vessels that can impact safety, especially in laparoscopic pancreaticoduo...

Jiahao Chen, Abousalam Abdoulkader Ahmed, Jieqiong Ge… in World Journal of Surgical Oncology (2024)

Article

MiR-146b-5p enriched bioinspired exosomes derived from fucoidan-directed induction mesenchymal stem cells protect chondrocytes in osteoarthritis by targeting TRAF6

Osteoarthritis (OA) is a common degenerative joint disease characterized by progressive cartilage degradation and inflammation. In recent years, mesenchymal stem cells (MSCs) derived exosomes (MSCs-Exo) have a...

Chao Lou, Hongyi Jiang, Zhongnan Lin, Tian **a, Weidan Wang… in Journal of Nanobiotechnology (2023)

Article

Erythropoietin suppresses osteoblast apoptosis and ameliorates steroid-induced necrosis of the femoral head in rats by inhibition of STAT1-caspase 3 signaling pathway

Steroid-induced avascular necrosis of the femoral head (SANFH) is characterized by osteoblast apoptosis, leading to a loss of bone structure and impaired hip joint function. It has been demonstrated that eryth...

Tingwen Cai, Siyuan Chen, Chenghu Wu, Chao Lou… in BMC Musculoskeletal Disorders (2023)

Article

3D covalent organic framework membrane with fast and selective ion transport

3D ionic covalent organic framework (COF) membranes, which are envisioned to be able to break the trade-off between ion conductivity and ion selectivity, are waiting for exploitation. Herein, we report the fab...

Tianhao Zhu, Yan Kong, Bohui Lyu, Li Cao, Benbing Shi… in Nature Communications (2023)

Article

Deep learning-driven precision control of dilution rate in multi-pass laser cladding: experiment and simulation

The continuous energy input can lead to heat accumulation in the multi-pass lap laser cladding, which results in a progressive increase in the dilution rate and deteriorates the quality of laser cladding. Prec...

Shichao Zhu, Wenzhen **a, Hamidreza Kamali… in The International Journal of Advanced Manu… (2023)

Article

Emerging roles of ferroptosis-related miRNAs in tumor metastasis

Ferroptosis, a novel mode of cell death dependent on iron and reactive oxygen species, has been extensively explored during malignant tumors metastasis. Ferroptosis can interact with multiple components of the...

Zhongyi Jiang, **g Zhou, Junqi Deng, Luohong Li, Ruifeng Wang… in Cell Death Discovery (2023)

Article

Retraction Note: Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells

Ruifeng Zhao, Qisheng Zuo, **a Yuan, Kai **, **g **, Ying Ding… in Nature Communications (2023)

Article

Coordinated regulation of vegetative phase change by brassinosteroids and the age pathway in Arabidopsis

Vegetative phase change in plants is regulated by a gradual decline in the level of miR156 and a corresponding increase in the expression of its targets, SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes. Gibber...

Bingying Zhou, Qing Luo, Yanghui Shen, Liang Wei, **a Song… in Nature Communications (2023)

Article

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

HIV-1 reverse transcriptase is one of the most attractive targets for the treatment of AIDS. However, the rapid emergence of drug-resistant strains and unsatisfactory drug-like properties seriously limit the c...

**angyi Jiang, Boshi Huang, Shawn Rumrill, David Pople… in Communications Chemistry (2023)

Article

Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation

Lung mast cells are important in host defense, and excessive proliferation or activation of these cells can cause chronic inflammatory disorders like asthma. Two parallel pathways induced by KIT–stem cell fact...

Youn Jung Choi, Ji-Seung Yoo, Kyle Jung, Logan Rice, Dokyun Kim… in Nature Communications (2023)