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A novel ratiometric fluorescent probe for differential detection of HSO3− and ClO− and application in cell imaging and tumor recognition

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  1. Article

    Open Access

    Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement

    Random-pattern skin flaps are commonly used and valuable tools in reconstructive surgery, however, post-operative random skin flap necrosis remains a major and common complication. Previous studies have sugges...

    Hongqiang Wu, Huanwen Chen, Zhilong Zheng, Jiafeng Li, Jian Ding… in Cell Death & Disease (2019)

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  2. Article

    Open Access

    FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

    Random-pattern skin flap is commonly used for surgical tissue reconstruction due to its ease and lack of axial vascular limitation. However, ischemic necrosis is a common complication, especially in distal par...

    Kailiang Zhou, Huanwen Chen, **ti Lin, Hui Xu, Hongqiang Wu… in Cell Death & Disease (2019)

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  3. Article

    Open Access

    STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

    Damaged deoxyribonucleic acid (DNA) is a primary pathologic factor for osteoarthritis (OA); however, the mechanism by which DNA damage drives OA is unclear. Previous research demonstrated that the cyclic GMP-A...

    Qiang Guo, **miao Chen, Jiaoxiang Chen, Gang Zheng, Chenglong **e… in Cell Death & Disease (2021)

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  4. Article

    Open Access

    GBP2 facilitates the progression of glioma via regulation of KIF22/EGFR signaling

    Identifying the mechanism of glioma progression is critical for diagnosis and treatment. Although studies have shown that guanylate-binding protein 2(GBP2) has critical roles in various cancers, its function i...

    Yeqing Ren, Biao Yang, Geng Guo, Jian** Zhang, Yanqi Sun… in Cell Death Discovery (2022)

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  5. Article

    Open Access

    MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis

    Intervertebral disc degeneration (IVDD) is a chronic age-related degenerative disease accompanied by complex pathophysiological mechanisms. Increasing evidence indicates that NLRP3 inflammasome mediated pyropt...

    Haiwei Ma, Chenglong **e, Zhengtai Chen, Gaolu He, Zihan Dai… in Cell Death Discovery (2022)

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  6. Article

    Open Access

    Stromal cells in the tumor microenvironment: accomplices of tumor progression?

    The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cel...

    Yan Zhao, Meili Shen, Liangqiang Wu, Haiqin Yang, Yixuan Yao… in Cell Death & Disease (2023)

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