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Article
Open AccessUncovering the role of ferroptosis in Bietti crystalline dystrophy and potential therapeutic strategies
Bietti crystalline dystrophy (BCD) is an inherited retinal degeneration disease caused by mutations in the CYP4V2 gene. Currently, there is no clinical therapy approach available for BCD patients. Previous resear...
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Article
Open AccessInfluence of thickness and strength on plastic instability in tailored steel structures
A mathematical model was intricately devised to explore the influence of continuous variations in thickness and mechanical properties on the performance of tailor rolled blanks (TRB) and tailor rolled tubes (T...
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Article
Open AccessNeoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial
Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...
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Article
Open AccessEvaluation of agricultural non-point source pollution using an in-situ and automated photochemical flow analysis system
Off-line leachate collection from agricultural landscapes cannot guarantee precise evaluation of agricultural non-point source (ANPS) due to geospatial variations, time, and transportation from the field to th...
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Article
Could Pretreatment Pan‑Immune‑Inflammation Value Predict Survival in Esophageal Cancer?
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Article
Calcium-based nanomaterials for cancer therapy
The aim of this paper is to review and analyze the advancements in the development and application of multifunctional calcium-based nanomaterials for cancer treatment, discussing their roles, challenges, and f...
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Article
How is the conceptual level of students associated with learning outcomes in math? Testing the mediating role of math anxiety and the moderating role of motivating style
The conceptual level is a learning style with growth characteristics that has important implications for both student learning and instruction. The main value of the conceptual level is the assertion that inst...
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Article
Survival analysis in pT1-3 and paracolic lymph-node invasion colorectal cancer: the prognostic role of positive paracolic lymph-node ratio for adjuvant chemotherapy
Several studies have observed that some stage III colorectal cancer (CRC) patients cannot benefit from standard adjuvant chemotherapy. However, there is no unified screening standard to date.
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Article
Author Correction: RNA polymerase II pausing regulates chromatin organization in erythrocytes
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Article
Open AccessGenome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive malignancy originating from plasmacytoid dendritic cells (pDCs) with a primarily cutaneous tropism followed by disseminati...
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Article
Open AccessDiamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair
The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA.
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Article
Open AccessBone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome
It is well known that high-fat diet (HFD)-induced metabolic syndrome plays a crucial role in cognitive decline and brain-blood barrier (BBB) breakdown. However, whether the bone-brain axis participates in this...
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Article
Open AccessEmpowering high-dimensional optical fiber communications with integrated photonic processors
Mode-division multiplexing (MDM) in optical fibers enables multichannel capabilities for various applications, including data transmission, quantum networks, imaging, and sensing. However, high-dimensional opt...
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Article
Open AccessTumor immune dysfunction and exclusion subtypes in bladder cancer and pan-cancer: a novel molecular subty** strategy and immunotherapeutic prediction model
Molecular subty** is expected to enable precise treatment. However, reliable subty** strategies for clinical application remains defective and controversial. Given the significance of tumor immune dysfunct...
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Article
Preparation of Bronze (CuSn10) Parts by Material Extrusion Process Using Paraffin-Based Binder
In this study, bronze (CuSn10) feedstocks were prepared using paraffin-based binders, which were extrusion printed to obtain green parts, and bronze samples were obtained by debinding and sintering the green p...
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Article
Laminated nanocrystalline-ferrite high saturation magnetic flux density composite core for use in high-frequency transformers
The low power density and high frequency loss of the core limits the miniaturization of high-frequency transformers (HFT) with an increase of the switching frequency. In this paper, a composite core with lamin...
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Article
Open AccessMethylation in cornea and corneal diseases: a systematic review
Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited. Thus, iden...
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Article
Open AccessStudy of the mandibular canal and its surrounding canals by multi-view cone-beam computed tomography
To determine the mandibular anatomical structures by observing cone-beam computed tomography (CBCT) from multiple angles.
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Article
In vivo safety evaluation method for nanomaterials for cancer therapy
Nanomaterials are extensively used in the diagnosis and treatment of cancer and other diseases because of their distinctive physicochemical properties, including the small size and ease of modification. The ap...
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Article
Open AccessKnockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway
Accumulating evidence indicates that aberrant non-SMC condensin II complex subunit D3 (NCAPD3) is associated with carcinogenesis of various cancers. Nevertheless, the biological role of NCAPD3 in the pathogene...
