179 Result(s)
-
Article
Control of slope-pattern on the deposition of fan-delta systems: a case study of the Upper Karamay Formation, Junggar Basin
The Mesozoic fan deltas in the north-west margin of the Junggar Basin, as important petroleum reservoirs, exhibited complex facies change and internal structures with strong heterogeneity which were controlled...
-
Article
Open AccessTraditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Repair of acute kidney injury (AKI) is a typical example of renal regeneration. AKI is characterized by tubular cell death, peritubular capillary (PTC) thinning, and immune system activation. After renal tubul...
-
Article
Open AccessCausal effect between gut microbiota and metabolic syndrome in European population: a bidirectional mendelian randomization study
Observational studies have reported that gut microbiota composition is associated with metabolic syndrome. However, the causal effect of gut microbiota on metabolic syndrome has yet to be confirmed.
-
Article
Open AccessTissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs
Proteolysis-targeting chimeras (PROTACs) are being developed for therapeutic use. However, they have poor pharmacokinetic profiles and their tissue distribution kinetics are not known.
-
Article
Using Self-Directed Humor to Regulate Emotion: Effects Comparison of Self-Enhancing Humor and Self-Defeating Humor
Humor is an effective strategy in regulating emotion. Whereas most previous studies have investigated the correlational relationship between self-directed humor and mental health, it is largely unknown whether...
-
Article
Changing patterns for cardiovascular disease and subtypes mortality attributable to ambient fine particulate matter pollution between China and India during 1990 to 2019
Long-term trends in PM2.5-attributable cardiovascular diseases (CVDs) and subtypes mortality remain unclear between China and India, facing dual challenges of aging and severe air pollution. We aim to compare lon...
-
Article
The genetic basis and process of inbreeding depression in an elite hybrid rice
Inbreeding depression refers to the reduced performance arising from increased homozygosity, a phenomenon that is the reverse of heterosis and exists among plants and animals. As a natural self-pollinated crop...
-
Article
A Fluorescent Probe for Hg2+ Specific Recognition Based on Xanthene and its Application in Food Detection and Cell Imaging
The mercury-loving unit aminothiourea was introduced into the xanthene fluorophore to synthesized the probe molecule NXH. NXH has a specific response to Hg2+, and with the addition of (0 ~ 50 µM) Hg2+, the fluore...
-
Article
Huamoxiang 3, a variety bred for steaming and cooking type of whole grain black rice
-
Article
Open AccessLifestyle factors, glycemic traits, and lipoprotein traits and risk of liver cancer: a Mendelian randomization analysis
The current state of knowledge on the relationship between lifestyle factors, glycemic traits, lipoprotein traits with liver cancer risk is still uncertain despite some attempts made by observational studies. ...
-
Article
A lightweight optimal design method for magnetic adhesion module of wall-climbing robot based on surrogate model and DBO algorithm
This research combines simulation technology, a surrogate model, and a dung beetle optimizer (DBO) to propose a structural optimization design method for lightweight adhesive modules. The structure of the wall...
-
Article
Dissection and validation of quantitative trait loci (QTLs) conferring grain size and grain weight in rice
Grain size and grain weight contribute greatly to the final grain yield in rice. In order to identify QTLs conferring grain size and grain weight, an F2 population derived from a cross between two indica rice acc...
-
Article
The relationship between Honesty-Humility and malevolent creativity: Sequential mediation models with prosocial moral emotional traits and prosocial tendencies
The present study aims to investigate the relationship between Honesty-Humility and malevolent creativity, by testing the sequential mediation models of prosocial moral emotional traits (gratitude, guilt, symp...
-
Article
Evaluation of tumor microvasculature with 3D ultrasound localization microscopy based on 2D matrix array
Evaluation of tumor microvascular morphology is of great significance in tumor diagnosis, therapeutic effect prediction, and surgical planning. Recently, two-dimensional ultrasound localization microscopy (2DU...
-
Article
Open AccessThe HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results
Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan. To develop a differentiated HER2 ADC, we chose an antibody that does not compe...
-
Chapter and Conference Paper
Improving Formability of Titanium Bipolar Plate via Hot Stam**
Due to the limited formability of ultra-thin titanium sheet at room temperature, it is difficult to form fine flow channels with increasing geometrical complexity of titanium bipolar plate. Premature occurrenc...
-
Article
Optimized interfacial compatibility of carbon fiber and epoxy resin via controllable thickness and activated ingredients of polydopamine layer
In this work, the trend in the performance of carbon fiber (CF) and its composite during self-polymerization of polydopamine (PDA) at carbon fiber surface was investigated by varying the self-polymerization ti...
-
Article
Self-knowledge distillation for surgical phase recognition
Advances in surgical phase recognition are generally led by training deeper networks. Rather than going further with a more complex solution, we believe that current models can be exploited better. We propose ...
-
Article
A 3-position modified naphthalimide fluorescent probe for reversible response to H2O2 and GSH and cell imaging
An “off–on–off” fluorescent probe NapEb for high selectivity and reversible response to H2O2 and GSH was synthesized. Inspired by the role of GSH in the human body, the –Se–N– bond in ebselen was successfully use...
-
Article
Photocatalysis-PMS oxidation system based on CQDs-doped carbon nitride nanosheets for degradation of residual drugs in water
Graphite-like carbon nitride (g-C3N4) is favored for its excellent physicochemical properties. However, the high complexation rate of photogenerated carriers greatly limits its practical applications. Based on th...