39 Result(s)
within
**gbo Zhou
Life Sciences
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Article
Inhibitory Effect of Puerarin on Lipopolysaccharide-triggered Inflammatory Responses of Bovine Kidney Cells
Puerarin (Pue), a flavonoid compound, possesses cytoprotective effects and LPS has been reported to induce renal inflammatory injury in bovine. However, whether Pue inhibits lipopolysaccharide (LPS)-induced in...
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Talaromyces sedimenticola sp. nov., isolated from the Mariana Trench
Two fungal strains (K-2T and S1) were isolated from the deepest ocean sediment of the Challenger Deep located in the Mariana Trench. The internal transcribed spacer (ITS) gene sequences of the isolates K-2T and S...
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Open AccessThe heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations
Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy among primary liver cancers, with an increasing overall incidence and poor prognosis. The intertumoral and intratumoral heterogeneity ...
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Open AccessJUNB affects hair follicle development and regeneration by promoting the proliferation of dermal papilla cells in goat
The process of hair follicle morphogenesis, development, and regeneration essentially depends on the interaction between skin epidermis and dermis, while dermal papilla (DP) cells play a vital role in this pro...
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Depth-Dependent Distribution of Prokaryotes in Sediments of the Manganese Crust on Nazimov Guyots of the Magellan Seamounts
Deep ocean polymetallic nodules, rich in cobalt, nickel, and titanium which are commonly used in high-technology and biotechnology applications, are being eyed for green energy transition through deep-sea mini...
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Open AccessGWAS of grain color and tannin content in Chinese sorghum based on whole-genome sequencing
Seventy-three QTL related to grain color and tannin content were identified in Chinese sorghum accessions, and a new recessive allelic variant of TAN2 gene was discovered.
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Open AccessCOVID-19 vaccination boosts the potency and breadth of the immune response against SARS-CoV-2 among recovered patients in Wuhan
The immunity of patients who recover from coronavirus disease 2019 (COVID-19) could be long lasting but persist at a lower level. Thus, recovered patients still need to be vaccinated to prevent reinfection by ...
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Growth in ever-increasing acidity condition enhanced the adaptation and bioleaching ability of Leptospirillum ferriphilum
Low pH eliminated the jarosite accumulation and improved the interfacial reaction rate during the bioleaching process. However, high acidity tends to make environments less hospitable, even for organisms that ...
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ARTP and NTG compound mutations improved Cry protein production and virulence of Bacillus thuringiensis X023
A high production mutated strain Bacillus thuringiensis X023PN (BtX023PN) was screened from the wild strain Bacillus thuringiensis X023 (BtX023) after atmospheric and room temperature plasma (ARTP) and nitrosogua...
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Article
Open AccessUBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer
UBR5, a HECT-domain E3 ubiquitin ligase, is an attractive therapeutic target for aggressive breast cancers. Defining the substrates of UBR5 is crucial for scientific understanding and clinical intervention. He...
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Effects of red/blue versus white LED light of different intensities on the growth and organic carbon and autotoxin secretion of hydroponic lettuce
Light is a crucial signal for plant growth, development, and secondary metabolism. Exploring the effects of light on autotoxin secretion in lettuce can be helpful for improving the utilization efficiency of th...
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Biocontrol potential and antifungal mechanism of a novel Streptomyces sichuanensis against Fusarium oxysporum f. sp. cubense tropical race 4 in vitro and in vivo
Most commercial banana cultivars are highly susceptible to Fusarium wilt caused by soilborne fungus Fusarium oxysporum f. sp. cubense (Foc), especially tropical race 4 (TR4). Biological control using antagonistic...
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Exosomal long non-coding RNA SOX2 overlap** transcript enhances the resistance to EGFR-TKIs in non-small cell lung cancer cell line H1975
Crosstalk between cancer cells and macrophages plays a crucial role in the development of cancer. In this study, our data showed that M1 macrophages attenuate, while M2 macrophages and tumor-associated macroph...
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Altering light–dark cycle at pre-harvest stage regulated growth, nutritional quality, and photosynthetic pigment content of hydroponic lettuce
Lettuce exposed to red (R) and blue (B) LEDs (4R:1B, 200 μmol·m−2·s−1) were cultivated hydroponically in an environmentally controlled plant factory to examine the effects of light–dark cycle (LDC) conversion at ...
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Article
Effects of constant versus fluctuating red–blue LED radiation on yield and quality of hydroponic purple-leaf lettuce
This study investigated the effects of constant light and alternating relatively high-intensity (500 µmol m−2 s−1) and low-intensity (150 µmol m−2 s−1) red–blue LEDs (4R:1B) on the biomass production and quality ...
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Open AccessActivating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1
Macrodactyly is a congenital malformation characterized by enlargement of bone and soft tissues in limbs, typically with excessive accumulation of adipose tissues. Although gain-of-function mutation of PIK3CA ...
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Open AccessActivating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly
Macrodactyly is a disabling congenital disease characterized by overgrowth of soft tissues and bones, which leads to finger enlargement and joint deformity. The mechanism of bone overgrowth in macrodactyly was...
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Open AccessGenome-wide variations analysis of sorghum cultivar Hongyingzi for brewing Moutai liquor
Hongyingzi is a sorghum (Sorghum bicolor L. Moench) cultivar for brewing Moutai liquor. For an overall understanding of the whole genome of Hongyingzi, we performed whole-genome resequencing technology to reveal ...
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Article
A high throughput method for screening deep-seeding tolerance in sorghum
Low soil moisture is a major abiotic stress wide spread in arid and semi-arid regions, limiting both seed germination and seedling establishment. Deep-seeding technique allows seeds to use the moisture in deep...
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Open AccessDeciphering microbial diversity associated with Fusarium wilt-diseased and disease-free banana rhizosphere soil
Fusarium wilt of banana (Musa spp.) caused by the fungal pathogen Fusarium oxysporum f. sp. cubense (Foc) is a typical soilborne disease, that severely devastates the banana industry worldwide, and soil microbial...
