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  1. Article

    Open Access

    Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation

    Retinal ganglion cells (RGCs) axons are the signal carriers of visual information between retina and brain. Therefore, they play one of the important roles affected in many optic neurodegenerative diseases lik...

    Mingying Hou, Zhengbo Shao, Shiqi Zhang, **nna Liu, Pan Fan… in Cell Death & Disease (2022)

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  2. Article

    Open Access

    Neuroprotective effects of bone marrow Sca-1+ cells against age-related retinal degeneration in OPTN E50K mice

    Glaucoma is characterized by retinal ganglion cell (RGC) death, the underlying mechanisms of which are still largely unknown. An E50K mutation in the Optineurin (OPTN) gene is a leading cause of normal-tension...

    **nna Liu, Mingying Hou, Shiqi Zhang, Yutong Zhao, Qi Wang… in Cell Death & Disease (2021)

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