5 Result(s)
within
**gbo Shao
Life Sciences
English
Biochemistry, general
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Article
Open AccessAge-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation
Retinal ganglion cells (RGCs) axons are the signal carriers of visual information between retina and brain. Therefore, they play one of the important roles affected in many optic neurodegenerative diseases lik...
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Article
Open AccessNeuroprotective effects of bone marrow Sca-1+ cells against age-related retinal degeneration in OPTN E50K mice
Glaucoma is characterized by retinal ganglion cell (RGC) death, the underlying mechanisms of which are still largely unknown. An E50K mutation in the Optineurin (OPTN) gene is a leading cause of normal-tension...
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Article
Open AccessThe E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro
The glaucoma-associated E50K mutation in optineurin (OPTN) is known to affect autophagy and cause the apoptosis of retinal ganglion cells (RGCs), but the pathogenic mechanism remains unclear. In this study, we...
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Article
Low PSI content limits the photoprotection of PSI and PSII in early growth stages of chlorophyll b-deficient wheat mutant lines
In vivo analyses of electron and proton transport-related processes as well as photoprotective responses were carried out at different stages of growth in chlorophyll b (Chl b)-deficient mutant lines (ANK-32A and...
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Chapter
Heat Signaling and Stress Responses in Photosynthesis
High temperature represents one of the most serious abiotic stress factors limiting plant photosynthesis, biomass production, and crop productivity. Photosynthetic apparatus is an important heat sensor in plan...
